Publications by authors named "Donald Sheppard"

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Evaluating the Potential of Galactosaminogalactan as a Diagnostic Target for Invasive Aspergillosis.
Takahiro Takazono, Kiyotaka Machida, Francois Le Mauff, Donald C Sheppard, Satoru Koga

Mycoses· October 2025

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Auto-aggregation in is driven by the Pel polysaccharide.
Deepa Raju, Siobhán A Turner, Karla Castro, Gregory B Whitfield, Daphnée Lamarche, Donald C Sheppard

mBio· August 2025

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Structural and functional analysis of Pseudomonas aeruginosa PelA provides insight into the modification of the Pel exopolysaccharide.
Jaime C Van Loon, François Le Mauff, Mario A Vargas, Stephanie Gilbert, Roland Pfoh, Donald C Sheppard

J Biol Chem· May 2025

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Fungal impacts on Earth's ecosystems.
Nicola T Case, Sarah J Gurr, Matthew C Fisher, David S Blehert, Charles Boone, Donald C Sheppard

Nature· February 2025

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CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.
Linda Heilig, Fariha Natasha, Nora Trinks, Vishukumar Aimanianda, Sarah Sze Wah Wong, Donald C Sheppard

PLoS Pathog· June 2024

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Understanding galactosaminogalactan biosynthesis: A few questions remain.
François Le Mauff, Donald C Sheppard

Cell Surf· December 2023

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Use of a human small airway epithelial cell line to study the interactions of with pulmonary epithelial cells.
Hong Liu, Jianfeng Lin, Quynh T Phan, Fabrice N Gravelat, Donald C Sheppard

mSphere· October 2023

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Identification and Quantification of Monosaccharides from Fungal Cell Walls and Exopolysaccharides by Gas Chromatography Coupled to Mass Spectrometry.
Pierre-Guy Millette, Josée Chabot, Donald C Sheppard, François Le Mauff

Curr Protoc· August 2023

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Use of a human small airway epithelial cell line to study the interactions of with pulmonary epithelial cells.
Hong Liu, Jianfeng Lin, Quynh T Phan, Fabrice N Gravelat, Donald C Sheppard

bioRxiv· April 2023

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Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence.
Erum Razvi, Gregory B Whitfield, Courtney Reichhardt, Julia E Dreifus, Alexandra R Willis, Donald C Sheppard

NPJ Biofilms Microbiomes· February 2023

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A B1a-natural IgG-neutrophil axis is impaired in viral- and steroid-associated aspergillosis.
Nicole Sarden, Sarthak Sinha, Kyle G Potts, Erwan Pernet, Carlos H Hiroki, Donald C Sheppard

Sci Transl Med· December 2022

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The future of fungi: threats and opportunities.
Nicola T Case, Judith Berman, David S Blehert, Robert A Cramer, Christina Cuomo, Donald C Sheppard

G3 (Bethesda)· November 2022

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Short-course antibiotic therapy: The next frontier in antimicrobial stewardship.
Donald Sheppard

Can Commun Dis Rep· November 2022

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Prevalence of antimicrobial-resistant organisms in smaller Canadian hospitals: Community, Rural, and Northern Acute Care Point Prevalence (CNAPP-19) Survey, 2019.
Shari Thomas, Denise Gravel Tropper, Braden Knight, Donald Sheppard, Tanya Lary

Can Commun Dis Rep· November 2022

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Filamentous fungal biofilms: Conserved and unique aspects of extracellular matrix composition, mechanisms of drug resistance and regulatory networks in Aspergillus fumigatus.
Shuai Liu, Francois Le Mauff, Donald C Sheppard, Shizhu Zhang

NPJ Biofilms Microbiomes· October 2022

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Tackling the emerging threat of antifungal resistance to human health.
Matthew C Fisher, Ana Alastruey-Izquierdo, Judith Berman, Tihana Bicanic, Elaine M Bignell, Donald C Sheppard

Nat Rev Microbiol· September 2022

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Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling.
Axel Dietschmann, Sebastian Schruefer, Stefanie Westermann, Fiona Henkel, Kirstin Castiglione, Donald C Sheppard

mBio· August 2022

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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases as Antibiofilm Agents in Acute Pulmonary Pseudomonas aeruginosa Infection.
Hanna Ostapska, Deepa Raju, Rachel Corsini, Melanie Lehoux, Ira Lacdao, Donald C Sheppard

Antimicrob Agents Chemother· August 2022

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Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells.
Quynh T Phan, Norma V Solis, Jianfeng Lin, Marc Swidergall, Shakti Singh, Donald C Sheppard

PLoS Pathog· July 2022

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Transfusable neutrophil progenitors as cellular therapy for the prevention of invasive fungal infections.
David B Sykes, Michelle M Martinelli, Paige Negoro, Shuying Xu, Katrina Maxcy, Donald C Sheppard

J Leukoc Biol· June 2022

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Author Correction: The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine.
François Le Mauff, Erum Razvi, Courtney Reichhardt, Piyanka Sivarajah, Matthew R Parsek, Donald C Sheppard

Commun Biol· June 2022

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The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine.
François Le Mauff, Erum Razvi, Courtney Reichhardt, Piyanka Sivarajah, Matthew R Parsek, Donald C Sheppard

Commun Biol· May 2022

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An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment.
Joshua D Kerkaert, François Le Mauff, Benjamin R Wucher, Sarah R Beattie, Elisa M Vesely, Donald C Sheppard

mBio· April 2022

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Co-Operative Biofilm Interactions between and through Secreted Galactosaminogalactan Exopolysaccharide.
Hanna Ostapska, François Le Mauff, Fabrice N Gravelat, Brendan D Snarr, Natalie C Bamford, Donald C Sheppard

J Fungi (Basel)· March 2022

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Preventing Biofilms on Indwelling Catheters by Surface-Bound Enzymes.
Dalal Asker, Tarek S Awad, Deepa Raju, Hiram Sanchez, Ira Lacdao, Donald C Sheppard

ACS Appl Bio Mater· December 2021

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