Publications by authors named "Dong-Jun Fu"

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Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity.
Dong-Jun Fu, Ting Wang

J Enzyme Inhib Med Chem· December 2023

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Synthesis of -2-phenylchromane Derivatives and Evaluation of the Antiproliferative Properties as Apoptosis Inducers in Cancer Cell Lines.
Yunfeng Zhang, Jiale Ma, Yujie Pei, Zeyuan Xie, Dong-Jun Fu

Anticancer Agents Med Chem· September 2023

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Targeting NEDD8-activating enzyme for cancer therapy: developments, clinical trials, challenges and future research directions.
Dong-Jun Fu, Ting Wang

J Hematol Oncol· July 2023

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Ras/Raf/MEK/ERK pathway axis mediated neurotoxicity induced by high-risk pesticide residue-Avermectin.
Ting Zhu, Xu Liu, Jian Song, Dong Li, Xiao-Jing Pang, Dong-Jun Fu

Environ Toxicol· May 2021

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Annual review of LSD1/KDM1A inhibitors in 2020.
Dong-Jun Fu, Jun Li, Bin Yu

Eur J Med Chem· March 2021

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Discovery of novel indole derivatives that inhibit NEDDylation and MAPK pathways against gastric cancer MGC803 cells.
Dong-Jun Fu, Xin-Xin Cui, Ting Zhu, Yan-Bing Zhang, Yang-Yang Hu

Bioorg Chem· February 2021

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Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors.
Dong-Jun Fu, Si-Meng Liu, Fu-Hao Li, Jia-Jia Yang, Jun Li

J Enzyme Inhib Med Chem· December 2020

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Novel piperidine derivatives as colchicine binding site inhibitors induce apoptosis and inhibit epithelial-mesenchymal transition against prostate cancer PC3 cells.
Dong-Jun Fu, Si-Meng Liu, Jia-Jia Yang, Jun Li

J Enzyme Inhib Med Chem· December 2020

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Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway.
Jian Song, Qiu-Lei Gao, Bo-Wen Wu, Ting Zhu, Xin-Xin Cui, Dong-Jun Fu

Eur J Med Chem· October 2020

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β-Lactams as promising anticancer agents: Molecular hybrids, structure activity relationships and potential targets.
Dong-Jun Fu, Yun-Feng Zhang, An-Qi Chang, Jun Li

Eur J Med Chem· September 2020

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Discovery of novel tertiary amide derivatives as NEDDylation pathway activators to inhibit the tumor progression in vitro and in vivo.
Dong-Jun Fu, Jian Song, Ting Zhu, Xiao-Jing Pang, Sheng-Hui Wang

Eur J Med Chem· April 2020

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Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagy.
Victor Pham, Raymond Rendon, Vinh X Le, Matthew Tippin, Dong-Jun Fu

Mol Carcinog· February 2020

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Corrigendum to "Synthesis and preliminary antiproliferative activity of new pteridin-7(8H)-one derivatives" [Eur. J. Med. Chem. 143 (2018) 1396-1405].
Zhong-Hua Li, Tao-Qian Zhao, Xue-Qi Liu, Bing Zhao, Chao Wang, Dong-Jun Fu

Eur J Med Chem· November 2019

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Discovery of indoline derivatives that inhibit esophageal squamous cell carcinoma growth by Noxa mediated apoptosis.
Dong-Jun Fu, Miaomiao Li, Sai-Yang Zhang, Jiang-Feng Li, Beibei Sha

Bioorg Chem· November 2019

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Discovery of novel chalcone-dithiocarbamates as ROS-mediated apoptosis inducers by inhibiting catalase.
Dong-Jun Fu, Jia-Huan Li, Jia-Jia Yang, Ping Li, Yan-Bing Zhang

Bioorg Chem· May 2019

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Identification of osimertinib (AZD9291) as a lysine specific demethylase 1 inhibitor.
Zhong-Rui Li, Feng-Zhi Suo, Bo Hu, Yan-Jia Guo, Dong-Jun Fu

Bioorg Chem· March 2019

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Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors.
Dong-Jun Fu, Ping Li, Bo-Wen Wu, Xin-Xin Cui, Cheng-Bin Zhao

Eur J Med Chem· March 2019

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Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues - Chlorpyrifos and Carbofuran via oxidative stress.
Dong-Jun Fu, Ping Li, Jian Song, Sai-Yang Zhang, Han-Zhong Xie

Toxicol In Vitro· February 2019

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Bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment exerting potent antiproliferative activity through microtubule destabilization.
Dong-Jun Fu, Jia-Jia Yang, Ping Li, Yu-Hui Hou, Sheng-Nan Huang

Eur J Med Chem· September 2018

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Synthesis and preliminary antiproliferative activity of new pteridin-7(8H)-one derivatives.
Zhong-Hua Li, Tao-Qian Zhao, Xue-Qi Liu, Bing Zhao, Chao Wang, Dong-Jun Fu

Eur J Med Chem· January 2018

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Design, synthesis and preliminary biological evaluation of 5,8-dihydropteridine-6,7-diones that induce apoptosis and suppress cell migration.
Peng-Fei Geng, Cong-Cong Wang, Zhong-Hua Li, Xiao-Ning Hu, Tao-Qian Zhao, Dong-Jun Fu

Eur J Med Chem· January 2018

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Molecular diversity of phenothiazines: design and synthesis of phenothiazine-dithiocarbamate hybrids as potential cell cycle blockers.
Dong-Jun Fu, Ruo-Han Zhao, Jia-Huan Li, Jia-Jia Yang, Ruo-Wang Mao

Mol Divers· November 2017

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Structure-Activity Relationship Studies of β-Lactam-azide Analogues as Orally Active Antitumor Agents Targeting the Tubulin Colchicine Site.
Dong-Jun Fu, Ling Fu, Ying-Chao Liu, Jun-Wei Wang, Yu-Qing Wang

Sci Rep· October 2017

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Discovery of 5,6-diaryl-1,2,4-triazines hybrids as potential apoptosis inducers.
Dong-Jun Fu, Jian Song, Yu-Hui Hou, Ruo-Han Zhao, Jia-Huan Li

Eur J Med Chem· September 2017

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Design and Antiproliferative Evaluation of Novel Sulfanilamide Derivatives as Potential Tubulin Polymerization Inhibitors.
Dong-Jun Fu, Ji-Feng Liu, Ruo-Han Zhao, Jia-Huan Li, Sai-Yang Zhang

Molecules· September 2017

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