Publications by authors named "Doohyun Lee"

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KF1601, a dual inhibitor of BCR::ABL1 and FLT3, overcomes drug resistance in FLT3 blast phase chronic myeloid leukemia.
Hyun-Jin Kwon, Ji Eun Shin, Amir Khan, So Yeon Park, Jiyoung Kim, Jee-Young Lee, Doohyun Lee, Seungyeon Lee, Wonhwa Lee

Mol Cancer· April 2025

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Extremely durable electrical impedance tomography-based soft and ultrathin wearable e-skin for three-dimensional tactile interfaces.
Kyubeen Kim, Jung-Hoon Hong, Kyubin Bae, Kyounghun Lee, Doohyun J Lee, Jung Woo Lee

Sci Adv· September 2024

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Stimulatory Effects of KPR-A148 on Osteoblast Differentiation and Bone Regeneration.
Soomin Lim, Ju Ang Kim, Taeho Lee, Doohyun Lee, Sang-Hyeon Nam

Tissue Eng Regen Med· August 2019

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Characterization of in vitro and in vivo metabolism of leelamine using liquid chromatography-tandem mass spectrometry.
Riya Shrestha, Jung Jae Jo, DooHyun Lee, Taeho Lee, Sangkyu Lee

Xenobiotica· May 2019

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Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1.
Hye Jung Ihn, Taeho Lee, Doohyun Lee, Jong-Sup Bae, Sang-Hyun Kim

Front Pharmacol· April 2019

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Identification of LEM-14 inhibitor of the oncoprotein NSD2.
Yunpeng Shen, Masayo Morishita, Doohyun Lee, Shinae Kim, Taeho Lee

Biochem Biophys Res Commun· January 2019

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A novel benzamide derivative protects ligature-induced alveolar bone erosion by inhibiting NFATc1-mediated osteoclastogenesis.
Hye Jung Ihn, Taeho Lee, Doohyun Lee, Ju Ang Kim, Kiryeong Kim, Youngkyun Lee, Hyun-Shik Lee

Toxicol Appl Pharmacol· September 2018

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Characterization of CYPs and UGTs Involved in Human Liver Microsomal Metabolism of Osthenol.
Pil Joung Cho, Sanjita Paudel, Doohyun Lee, Yun Ji Jin, GeunHyung Jo, Sangkyu Lee, Taeho Lee

Pharmaceutics· August 2018

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Isolation, Synthesis, and Antisepsis Effects of a C-Methylcoumarinochromone Isolated from Abronia nana Cell Culture.
Wonhwa Lee, Doohyun Lee, Yuri Lee, Taeho Lee, Kyung-Sik Song

J Nat Prod· May 2018

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OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo.
Hye Jung Ihn, Taeho Lee, Ju Ang Kim, Doohyun Lee, Nam Doo Kim

PLoS One· August 2017

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Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound.
Kyunghye Park, Hye Eun Lee, Sun Hee Lee, Doohyun Lee, Taeho Lee, You Mie Lee

Oncotarget· January 2017

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Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway.
Hye Jung Ihn, Doohyun Lee, Taeho Lee, Sang-Hyun Kim, Hong-In Shin

PLoS One· June 2016

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Lipidomic platform for structural identification of skin ceramides with α-hydroxyacyl chains.
Zhexue Wu, Jong Cheol Shon, Doohyun Lee, Kab-Tae Park, Chang Seo Park, Taeho Lee, Hye Suk Lee

Anal Bioanal Chem· March 2016

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Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer.
JuHee Sim, Woongsik Nam, Doohyun Lee, Suyoun Lee, Hungchan O, Taeho Lee, Sangkyu Lee

Arch Pharm Res· February 2016

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Solid-Phase Synthesis of 1,3,7,8-Tetrasubstituted Xanthine Derivatives on Traceless Solid Support.
Doohyun Lee, Seungyeon Lee, Kwang-Hyeon Liu, Jong-Sup Bae, Dong Jae Baek, Taeho Lee

ACS Comb Sci· January 2016

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The 1,2,3-triazole derivative KP-A021 suppresses osteoclast differentiation and function by inhibiting RANKL-mediated MEK-ERK signaling pathway.
Hye Jung Ihn, Doohyun Lee, Taeho Lee, Hong-In Shin, Yong Chul Bae

Exp Biol Med (Maywood)· December 2015

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Efficient Syntheses of 1,2,3-Triazoloamide Derivatives Using Solid- and Solution-Phase Synthetic Approaches.
Doohyun Lee, Daehun Kim, Seungyeon Lee, Taegeum Kim, Joobin Kim, Sangkyu Lee, Taeho Lee

Molecules· November 2015

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Serendipitous discovery of 2-((phenylsulfonyl)methyl)-thieno[3,2-d]pyrimidine derivatives as novel HIV-1 replication inhibitors.
Junwon Kim, Jeongjin Kwon, Doohyun Lee, Suyeon Jo, Dong-Sik Park, Jinhwa Lee

Bioorg Med Chem Lett· December 2014

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Identification of metabolites of N-(5-benzoyl-2-(4-(2-methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide including CYP3A4-mediated C-demethylation in human liver microsomes with high-resolution/high-accuracy tandem mass.
Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Taeho Lee, Sangkyu Lee

Drug Metab Dispos· August 2014

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A derivative of imidazobenzimidazole, ML106, inhibits melanin synthesis via p38 MAPK activation.
Su Yeon Kim, Seung Hoon Lee, Jun Seob Shin, Doohyun Lee, Taeho Lee

Pharmazie· May 2014

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Emodin-6-O-β-D--glucoside inhibits high-glucose-induced vascular inflammation.
Wonhwa Lee, Sae-Kwang Ku, Doohyun Lee, Taeho Lee, Jong-Sup Bae

Inflammation· April 2014

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CYP2J2 and CYP2C19 are the major enzymes responsible for metabolism of albendazole and fenbendazole in human liver microsomes and recombinant P450 assay systems.
Zhexue Wu, Doohyun Lee, Jeongmin Joo, Jung-Hoon Shin, Wonku Kang, Do Yup Lee, Su-Jun Lee, Hye Suk Lee, Taeho Lee

Antimicrob Agents Chemother· November 2013

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Determination of leelamine in mouse plasma by LC-MS/MS and its pharmacokinetics.
Min Song, Doohyun Lee, Taeho Lee, Sangkyu Lee

J Chromatogr B Analyt Technol Biomed Life Sci· July 2013

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In vitro metabolism of obovatol and its effect on cytochrome P450 enzyme activities in human liver microsomes.
Jeongmin Joo, Doohyun Lee, Zhexue Wu, Jung-Hoon Shin, Hye Suk Lee, Su-Jun Lee, Taeho Lee

Biopharm Drug Dispos· May 2013

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Synthesis and biological evaluation of triazolothienopyrimidine derivatives as novel HIV-1 replication inhibitors.
Junwon Kim, Jeongjin Kwon, Doohyun Lee, Suyeon Jo, Dong-Sik Park, Jinhwa Lee

Bioorg Med Chem Lett· January 2013

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