Publications by authors named "Dora Brites"

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Assessment of the therapeutic effect of IGS2.7, a CK1δ protein kinase inhibitor, in combination with riluzole for the treatment of ALS-associated TDP-43 proteinopathy.
Marta Gomez-Almeria, Loreto Martinez-Gonzalez, Ana Teresa Matos, Carmen Rodriguez-Cueto, Ana Rita Vaz, Dora Brites

Neuropharmacology· December 2025

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Depression- and exercise-associated stimuli exert contrasting effects on neural stem cell activity and paracrine signaling.
André L Simão, Sónia Sá Santos, João A Ferreira Moreira, Francisca Silva, Raúl Oliveira, Dora Brites

Biochim Biophys Acta Mol Basis Dis· November 2025

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Comparative Neuroplasticity in Frontal- and Lateral-Eyed Mammals With Induced-Binocular Vision Dysfunction: Insights From Monocular Deprivation Models.
Fábio Leite do Amaral Júnior, Thalyta Alves Rodrigues, Nonata Lúcia Trévia da Silva, Izabela Negrão Almeida Diniz, Luciana Negrão Almeida de Morais, Dora Brites

Eur J Neurosci· July 2025

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Exosomes enriched with miR-124-3p show therapeutic potential in a new microfluidic triculture model that recapitulates neuron-glia crosstalk in Alzheimer's disease.
Artemizia Évora, Gonçalo Garcia, Ana Rubi, Eleonora De Vitis, Ana Teresa Matos, Dora Brites

Front Pharmacol· March 2025

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Intriguing astrocyte responses in CA1 to reduced and rehabilitated masticatory function: Dorsal and ventral distinct perspectives in adult mice.
Micaele Maria Lopes Castro, Fabio Leite do Amaral Junior, Fabíola de Carvalho Chaves de Siqueira Mendes, Daniel Clive Anthony, Dora Maria Tuna de Oliveira Brites

Arch Oral Biol· January 2025

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The Hidden Dangers of Sedentary Living: Insights into Molecular, Cellular, and Systemic Mechanisms.
Daniel Guerreiro Diniz, João Bento-Torres, Victor Oliveira da Costa, Josilayne Patricia Ramos Carvalho, Alessandra Mendonça Tomás, Dora Brites

Int J Mol Sci· October 2024

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Spatiotemporal Dysregulation of Neuron-Glia Related Genes and Pro-/Anti-Inflammatory miRNAs in the Mouse Model of Alzheimer's Disease.
Marta Ianni, Miriam Corraliza-Gomez, Tiago Costa-Coelho, Mafalda Ferreira-Manso, Sara Inteiro-Oliveira, Dora Brites

Int J Mol Sci· August 2024

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Contrasting Disease Progression, Microglia Reactivity, Tolerance, and Resistance to Infection in Two Mouse Strains.
Daniel G Diniz, Jhonnathan H P de Oliveira, Luma C F Guerreiro, Gabriel C de Menezes, Alexa C L de Assis, Dora Brites

Biomedicines· June 2024

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Unravelling the triad of neuroinvasion, neurodissemination, and neuroinflammation of human immunodeficiency virus type 1 in the central nervous system.
Marta Calado, Rita Ferreira, David Pires, Quirina Santos-Costa, Elsa Anes, Dora Brites

Rev Med Virol· May 2024

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Exploratory Analysis of MicroRNA Alterations in a Neurodevelopmental Mouse Model for Autism Spectrum Disorder and Schizophrenia.
Susana García-Cerro, Ana Gómez-Garrido, Gonçalo Garcia, Benedicto Crespo-Facorro, Dora Brites

Int J Mol Sci· February 2024

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Genes, inflammatory response, tolerance, and resistance to virus infections in migratory birds, bats, and rodents.
Patrick Douglas Corrêa Pereira, Daniel Guerreiro Diniz, Emanuel Ramos da Costa, Nara Gyzely de Morais Magalhães, Anderson de Jesus Falcão da Silva, Dora Brites

Front Immunol· September 2023

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Bile acids profile and redox status in healthy infants.
Ermelinda Santos Silva, Susana Rocha, Rita Candeias Ramos, Helena Coutinho, Cristina Catarino, Dora Brites

Pediatr Res· June 2023

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Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies.
Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Dora Brites

Stem Cell Reports· May 2023

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Microglia states and nomenclature: A field at its crossroads.
Rosa C Paolicelli, Amanda Sierra, Beth Stevens, Marie-Eve Tremblay, Adriano Aguzzi, Dora Brites

Neuron· November 2022

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Emerging Role of miR-21-5p in Neuron-Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer's Disease.
Gonçalo Garcia, Sara Pinto, Sofia Ferreira, Daniela Lopes, Maria João Serrador, Dora Brites

Cells· October 2022

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Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice.
Marta Barbosa, Marta Santos, Nídia de Sousa, Sara Duarte-Silva, Ana Rita Vaz, Dora Brites

Biomedicines· August 2022

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The Sedentary Lifestyle and Masticatory Dysfunction: Time to Review the Contribution to Age-Associated Cognitive Decline and Astrocyte Morphotypes in the Dentate Gyrus.
Fabíola de Carvalho Chaves de Siqueira Mendes, Marina Negrão Frota de Almeida, Manoela Falsoni, Marcia Lorena Ferreira Andrade, André Pinheiro Gurgel Felício, Dora Brites

Int J Mol Sci· June 2022

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Protective Signature of IFNγ-Stimulated Microglia Relies on miR-124-3p Regulation From the Secretome Released by Mutant APP Swedish Neuronal Cells.
Gonçalo Garcia, Adelaide Fernandes, Frank Stein, Dora Brites

Front Pharmacol· May 2022

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Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes.
Cátia Gomes, Catarina Sequeira, Shibi Likhite, Cassandra N Dennys, Stephen J Kolb, Dora Brites

Cells· April 2022

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Challenges in the Development of Drug Delivery Systems Based on Small Extracellular Vesicles for Therapy of Brain Diseases.
Gecioni Loch-Neckel, Ana Teresa Matos, Ana Rita Vaz, Dora Brites

Front Pharmacol· March 2022

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S100B inhibition protects from chronic experimental autoimmune encephalomyelitis.
Catarina Barros, Andreia Barateiro, Alexandre Neto, Beatriz Soromenho, Afonso P Basto, Dora Brites

Brain Commun· March 2022

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Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD Mice.
Adelaide Fernandes, Cláudia Caldeira, Carolina Cunha, Elisabete Ferreiro, Ana Rita Vaz, Dora Brites

Cells· January 2022

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Human iPSC-derived hippocampal spheroids: An innovative tool for stratifying Alzheimer disease patient-specific cellular phenotypes and developing therapies.
Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Dora Brites

Stem Cell Reports· November 2021

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Unwanted Exacerbation of the Immune Response in Neurodegenerative Disease: A Time to Review the Impact.
Amanda de Oliveira Ferreira Leite, João Bento Torres Neto, Renata Rodrigues Dos Reis, Luciane Lobato Sobral, Aline Cristine Passos de Souza, Dora Brites

Front Cell Neurosci· October 2021

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Neuronal Dynamics and miRNA Signaling Differ between SH-SY5Y and Mutant iPSC-Derived AD Models upon Modulation with miR-124 Mimic and Inhibitor.
Gonçalo Garcia, Sara Pinto, Mar Cunha, Adelaide Fernandes, Jari Koistinaho, Dora Brites

Cells· September 2021

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