Publications by authors named "Doris Germain"

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Targeting the Mitochondrial Protease ClpP for Anticancer Therapy.
Zhongli Xu, Dmitry Pokushalov, Md Kabir, Youngeun Lee, Mrittika Chattopadhyay, Doris Germain

J Med Chem· October 2025

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Differential ER stress responses during lactation and postpartum outcomes in mice depending on their mitochondrial genotype.
Mrittika Chattopadhyay, Edmund Charles Jenkins, William Janssen, Thelma Mashaka, Doris Germain

Nat Commun· July 2025

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Maternal ancestry reveals cyclical aging of the mammary gland.
Doris Germain, Thelma Mashaka, Mrittika Chattopadhyay, Dmitry Polushakov, Miguel Torres-Martin

Res Sq· November 2024

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Idiosyncratic nature of lactation reveals link to breast cancer risk.
Mrittika Chattopadhyay, Edmund Charles Jenkins, William Janssen, Thelma Mashaka, Doris Germain

Res Sq· June 2024

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Expression of Concern: Estrogen receptor mediates a distinct mitochondrial unfolded protein response.
Luena Papa, Doris Germain

J Cell Sci· September 2023

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Age alters the oncogenic trajectory toward luminal mammary tumors that activate unfolded proteins responses.
Edmund Charles Jenkins, Mrittika Chattopadhyay, Maria Gomez, Denis Torre, Avi Ma'ayan, Doris Germain

Aging Cell· October 2022

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Can THEM6 targeting stop resistance to prostate cancer treatment?
Mrittika Chattopadhyay, Doris Germain

EMBO Mol Med· March 2022

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The portrait of liver cancer is shaped by mitochondrial genetics.
Mrittika Chattopadhyay, Edmund Charles Jenkins, Ana Victoria Lechuga-Vieco, Kai Nie, Maria Isabel Fiel, Doris Germain

Cell Rep· January 2022

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Folding Mitochondrial-Mediated Cytosolic Proteostasis Into the Mitochondrial Unfolded Protein Response.
Edmund Charles Jenkins, Mrittika Chattopadhyay, Doris Germain

Front Cell Dev Biol· September 2021

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Are the estrogen receptor and SIRT3 axes of the mitochondrial UPR key regulators of breast cancer sub-type determination according to age?
Edmund Charles Jenkins, Mrittika Chattopadhyay, Doris Germain

Aging Cancer· September 2021

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Doxycycline promotes proteasome fitness in the central nervous system.
Edmund Charles Jenkins, Matthew J O'Connell, Giovanni Manfredi, Doris Germain

Sci Rep· August 2021

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Raloxifene is a Female-specific Proteostasis Therapeutic in the Spinal Cord.
Edmund Charles Jenkins, Gabriella Casalena, Maria Gomez, Dazhi Zhao, Timothy C Kenny, Doris Germain

Endocrinology· February 2021

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The Multi-Faced Role of PAPP-A in Post-Partum Breast Cancer: IGF-Signaling is Only the Beginning.
Edmund Charles Jenkins, Samantha O Brown, Doris Germain

J Mammary Gland Biol Neoplasia· September 2020

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Postpartum Involution and Cancer: An Opportunity for Targeted Breast Cancer Prevention and Treatments?
Virginia F Borges, Traci R Lyons, Doris Germain, Pepper Schedin

Cancer Res· May 2020

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Proteasome mapping reveals sexual dimorphism in tissue-specific sensitivity to protein aggregations.
Edmund Charles Jenkins, Nagma Shah, Maria Gomez, Gabriella Casalena, Dazhi Zhao, Doris Germain

EMBO Rep· April 2020

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Mitohormesis, UPR, and the Complexity of Mitochondrial DNA Landscapes in Cancer.
Timothy C Kenny, Maria L Gomez, Doris Germain

Cancer Res· December 2019

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Collagen and PAPP-A in the Etiology of Postpartum Breast Cancer.
Elizabeth Slocum, Doris Germain

Horm Cancer· December 2019

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Cross talk between SOD1 and the mitochondrial UPR in cancer and neurodegeneration.
Maria Gomez, Doris Germain

Mol Cell Neurosci· July 2019

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SOD1 is essential for oncogene-driven mammary tumor formation but dispensable for normal development and proliferation.
Maria L Gomez, Nagma Shah, Timothy C Kenny, Edmund C Jenkins, Doris Germain

Oncogene· July 2019

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Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2.
Elizabeth Slocum, Amanda Craig, Augusto Villanueva, Doris Germain

Breast Cancer Res· May 2019

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Mitohormesis Primes Tumor Invasion and Metastasis.
Timothy C Kenny, Amanda J Craig, Augusto Villanueva, Doris Germain

Cell Rep· May 2019

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Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap.
Youngmin A Lee, Luke A Noon, Kemal M Akat, Maria D Ybanez, Ting-Fang Lee, Doris Germain

Nat Commun· November 2018

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From discovery of the CHOP axis and targeting ClpP to the identification of additional axes of the UPRmt driven by the estrogen receptor and SIRT3.
Timothy C Kenny, Doris Germain

J Bioenerg Biomembr· August 2017

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The Mitochondrial Unfolded Protein Response as a Non-Oncogene Addiction to Support Adaptation to Stress during Transformation in Cancer and Beyond.
Timothy C Kenny, Giovanni Manfredi, Doris Germain

Front Oncol· July 2017

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Randomized phase II trial of fulvestrant alone or in combination with bortezomib in hormone receptor-positive metastatic breast cancer resistant to aromatase inhibitors: a New York Cancer Consortium trial.
Kerin Adelson, Bhuvaneswari Ramaswamy, Joseph A Sparano, Paul J Christos, John J Wright, Doris Germain

NPJ Breast Cancer· December 2016

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