Publications by authors named "Doug Higgs"

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Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions.
Hangpeng Li, James L T Dalgleish, George Lister, Maria Julia Maristany, Jan Huertas, Doug Higgs

Cell· December 2025

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Understanding fundamental principles of enhancer biology at a model locus: Analysing the structure and function of an enhancer cluster at the α-globin locus.
Mira Kassouf, Seren Ford, Joseph Blayney, Doug Higgs

Bioessays· October 2023

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Defining genome architecture at base-pair resolution.
Peng Hua, Mohsin Badat, Lars L P Hanssen, Lance D Hentges, Nicholas Crump, Doug R Higgs

Nature· July 2021

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Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia.
Sachith Mettananda, Nirmani Yasara, Christopher A Fisher, Stephen Taylor, Richard Gibbons, Doug Higgs

Sci Rep· August 2019

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Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell- and tissue-specific DNase footprints.
Ron Schwessinger, Maria C Suciu, Simon J McGowan, Jelena Telenius, Stephen Taylor, Doug R Higgs

Genome Res· October 2017

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A novel 33-Gene targeted resequencing panel provides accurate, clinical-grade diagnosis and improves patient management for rare inherited anaemias.
Noémi B A Roy, Edward A Wilson, Shirley Henderson, Katherine Wray, Christian Babbs, Doug Higgs

Br J Haematol· October 2016

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Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.
Jenny C Taylor, Hilary C Martin, Stefano Lise, John Broxholme, Jean-Baptiste Cazier, Doug Higgs

Nat Genet· July 2015

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The worm has turned: unexpected similarities between the transcription of enhancers and promoters in the worm and mammalian genomes.
Bryony J Graham, Deborah Hay, Jim Hughes, Doug Higgs

Bioessays· February 2014

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Chromatin signatures at transcriptional start sites separate two equally populated yet distinct classes of intergenic long noncoding RNAs.
Ana C Marques, Jim Hughes, Bryony Graham, Monika S Kowalczyk, Doug R Higgs

Genome Biol· November 2013

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PhenCode: connecting ENCODE data with mutations and phenotype.
Belinda Giardine, Cathy Riemer, Tim Hefferon, Daryl Thomas, Fan Hsu, Doug Higgs

Hum Mutat· June 2007

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The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies.
Yutong Xue, Richard Gibbons, Zhijiang Yan, Dafeng Yang, Tarra L McDowell, Doug Higgs

Proc Natl Acad Sci U S A· September 2003

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Characterization of embryonic globin genes of the zebrafish.
Alison Brownlie, Candace Hersey, Andrew C Oates, Barry H Paw, Arnold M Falick, Doug Higgs

Dev Biol· March 2003

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