Publications by authors named "Doug Leipold"

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Monomethyl auristatin E (MMAE), a payload for multiple antibody drug conjugates (ADCs), demonstrates differential red blood cell partitioning across human and animal species.
Victor Yip, Ola M Saad, Doug Leipold, Chunze Li, Amrita Kamath

Xenobiotica· August 2024

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Anti-Lymphocyte Antigen 6 Complex, Locus E--Cyclopropabenzindol-4-One-Dimer Antibody-Drug Conjugate That Forms Adduct with 1-Microglobulin Demonstrates Slower Systemic Antibody Clearance and Reduced Tumor Distribution in Animals.
Victor Yip, Isabel Figueroa, Brandon Latifi, Shab Masih, Carl Ng, Doug Leipold

Drug Metab Dispos· December 2020

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Prediction of non-linear pharmacokinetics in humans of an antibody-drug conjugate (ADC) when evaluation of higher doses in animals is limited by tolerability: Case study with an anti-CD33 ADC.
Isabel Figueroa, Doug Leipold, Steve Leong, Bing Zheng, Montserrat Triguero-Carrasco

MAbs· July 2018

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Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity.
BinQing Wei, Janet Gunzner-Toste, Hui Yao, Tao Wang, Jing Wang, Doug Leipold

J Med Chem· February 2018

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