Publications by authors named "Douglas D Fraser"

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Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function.
Cristiana Iosef, Michael J Knauer, Michael Nicholson, Logan R Van Nynatten, Gediminas Cepinskas, Sorin Draghici, Victor K M Han, Douglas D Fraser

June 2023

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Differential protein expression and enriched pathways in pediatric sepsis: identification of novel brain-associated biomarkers revealed through proteomic profiling.
Vincenzo Stranges, David Tweddell, Enis Cela, Maria Morello, Mark Daley, Douglas D Fraser

Mol Med· November 2025

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Predictive enrichment using biomarkers in studies of critically-ill patients with sepsis: a systematic review.
Logan R Van Nynatten, Diyaa Bokhary, Michelle Yee Suet Wong, Jocelyn Wang, Henri Fero, Douglas D Fraser

Crit Care· November 2025

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Divergent biological pathways distinguish community-acquired pneumonia from COVID-19 despite similar plasma cytokine profiles.
Douglas D Fraser, Logan R Van Nynatten, David Tweddell, Mark Daley, James A Russell

Respir Res· August 2025

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Effect of Inhaled Volatile and IV Anesthetics on Biological Markers of Inflammation in Adult ICU and Thoracic Surgical Patients: A Systematic Review and Meta-Analysis.
Soroush Rouhani, Sanchit Gupta, Hira Raheel, Aggie Duan Gao, Ciara Hanley, Douglas D Fraser

Crit Care Explor· July 2025

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Metabolomic alterations in human brain microvascular endothelial cells induced by traumatic injury.
Enis Cela, David Tweddell, Eric K Patterson, Mark Daley, Gediminas Cepinskas, Douglas D Fraser

Metabolomics· June 2025

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Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity.
Douglas D Fraser, Swapan Roy, Matt Kuruc, Maritza Quintero, Logan R Van Nynatten

Exp Biol Med (Maywood)· May 2025

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Neutralizing antibodies to SARS-CoV-2 variants of concern: a pediatric surveillance study.
Douglas D Fraser, Devika Singh, Enis Cela, Maitray A Patel, Maysaa Assaf

Sci Rep· April 2025

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Efficient and scalable construction of clinical variable networks for complex diseases with RAMEN.
Yiwei Xiong, Jingtao Wang, Xiaoxiao Shang, Tingting Chen, Douglas D Fraser

Cell Rep Methods· April 2025

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Application of Human Plasma/Serum to Cell Culture In Vitro: A Translational Research Approach to Better Define Disease Mechanisms.
Enis Cela, Eric K Patterson, Sean E Gill, Gediminas Cepinskas, Douglas D Fraser

Clin Transl Sci· March 2025

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Putative biomarkers of hepatic dysfunction in critically ill sepsis patients.
Logan R Van Nynatten, Maitray A Patel, Mark Daley, Michael R Miller, Gediminas Cepinskas, Douglas D Fraser

Clin Exp Med· January 2025

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Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis.
Paolo Spagnolo, Enis Cela, Maitray A Patel, David Tweddell, Mark Daley, Douglas D Fraser

Mol Med· January 2025

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Investigating the Risk Factors Associated With Acute Neurologic Dysfunction in Pediatric Hyperglycemic Emergencies on Transport.
Grant Scollay, Zach Cantor, Douglas D Fraser, Russell MacDonald, Candice McGahern

Pediatr Emerg Care· December 2024

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Metabolomic signature of pediatric diabetic ketoacidosis: key metabolites, pathways, and panels linked to clinical variables.
Paolo Spagnolo, David Tweddell, Enis Cela, Mark Daley, Cheril Clarson, Douglas D Fraser

Mol Med· December 2024

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Circulating IL-17F, but not IL-17A, is elevated in severe COVID-19 and leads to an ERK1/2 and p38 MAPK-dependent increase in ICAM-1 cell surface expression and neutrophil adhesion on endothelial cells.
Jérôme Bédard-Matteau, Antoine Soulé, Katelyn Yixiu Liu, Lyvia Fourcade, Douglas D Fraser

Front Immunol· November 2024

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Endocrine dysregulation in COVID-19: molecular mechanisms and insights.
Cristiana Iosef, Andrei M Matusa, Victor K M Han, Douglas D Fraser

Front Endocrinol (Lausanne)· November 2024

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Plasma Biomarkers of Traumatic Brain Injury in Adolescents With Sport-Related Concussion.
Jason B Tabor, Linden C Penner, Jean-Michel Galarneau, Nik Josafatow, Jennifer Cooper, Douglas D Fraser

JAMA Netw Open· September 2024

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Post-Intensive Care Sequelae in Pediatrics-Results of an Early Rehabilitation Implementation Study.
Karen Choong, Douglas D Fraser, Saoirse Cameron, Carlos Cuello, Sylvie Debigaré

Pediatr Crit Care Med· June 2024

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Correction: Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients.
Tomonori Kaneko, Sally Ezra, Rober Abdo, Courtney Voss, Shanshan Zhong, Douglas D Fraser

Clin Proteomics· May 2024

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A reduced proteomic signature in critically ill Covid-19 patients determined with plasma antibody micro-array and machine learning.
Maitray A Patel, Mark Daley, Logan R Van Nynatten, Marat Slessarev, Gediminas Cepinskas, Douglas D Fraser

Clin Proteomics· May 2024

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The plasma proteome differentiates the multisystem inflammatory syndrome in children (MIS-C) from children with SARS-CoV-2 negative sepsis.
Maitray A Patel, Douglas D Fraser, Mark Daley, Gediminas Cepinskas, Noemi Veraldi

Mol Med· April 2024

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Pediatric sepsis inflammatory blood biomarkers that correlate with clinical variables and severity of illness scores.
Sean Leonard, Hailey Guertin, Natalya Odoardi, Michael R Miller, Maitray A Patel, Douglas D Fraser

J Inflamm (Lond)· March 2024

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Early Rehabilitation in Critically ill Children: A Two Center Implementation Study.
Karen Choong, Douglas D Fraser, Ahmed Al-Farsi, Saif Awlad Thani, Saoirse Cameron

Pediatr Crit Care Med· February 2024

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Kinome and phosphoproteome reprogramming underlies the aberrant immune responses in critically ill COVID-19 patients.
Tomonori Kaneko, Sally Ezra, Rober Abdo, Courtney Voss, Shanshan Zhong, Douglas D Fraser

Clin Proteomics· February 2024

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Pharmacokinetics of recombinant human annexin A5 (SY-005) in patients with severe COVID-19.
Brent J Tschirhart, Xiangru Lu, Aristide Laurel Mokale Kognou, Claudio M Martin, Marat Slessarev, Douglas D Fraser

Front Pharmacol· January 2024

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A novel multiplex biomarker panel for profiling human acute and chronic kidney disease.
Logan R Van Nynatten, Michael R Miller, Maitray A Patel, Mark Daley, Guido Filler, Douglas D Fraser

Sci Rep· December 2023

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