Publications by authors named "Douglas Houston"

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SCORCH2: A Generalized Heterogeneous Consensus Model for High-Enrichment Interaction-Based Virtual Screening.
Lin Chen, Vincent Blay, Pedro J Ballester, Douglas R Houston

Adv Sci (Weinh)· November 2025

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Interdomain disulfide bonds of rabbit kappa light chain allotypes influence mouse-rabbit chimeric antibody performance.
Yang-Nim Park, Douglas W Houston

bioRxiv· September 2025

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Open-source antibodies as a path to enhanced research reproducibility and transparency.
Meghan Rego, Douglas W Houston, Melina Fan, Karl D Murray, James S Trimmer

N Biotechnol· July 2025

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CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13.
Oleksandra Herasymenko, Madhushika Silva, Abd Al-Aziz A Abu-Saleh, Ayaz Ahmad, Jesus Alvarado-Huayhuaz, Douglas R Houston

J Chem Inf Model· July 2025

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A consensus platform for antibody characterization.
Riham Ayoubi, Joel Ryan, Sara Gonzalez Bolivar, Charles Alende, Vera Ruiz Moleon, Douglas W Houston

Nat Protoc· June 2025

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Sponge bHLH Gene Expression in Disrupts Inner Ear and Lateral Line Neurosensory Development and Otic Afferent Pathfinding.
Karen L Elliott, Clayton Gordy, Hannah Ingvalson, Charles Holliday, Jessica Halyko, Douglas W Houston

Int J Mol Sci· June 2025

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Antibody characterization is critical to enhance reproducibility in biomedical research.
Richard A Kahn, Harvinder Virk, Carl Laflamme, Douglas W Houston, Nicole K Polinski

Elife· August 2024

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AutoDock-SS: AutoDock for Multiconformational Ligand-Based Virtual Screening.
Boyang Ni, Haoying Wang, Huda Kadhim Salem Khalaf, Vincent Blay, Douglas R Houston

J Chem Inf Model· May 2024

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From intuition to AI: evolution of small molecule representations in drug discovery.
Miles McGibbon, Steven Shave, Jie Dong, Yumiao Gao, Douglas R Houston

Brief Bioinform· November 2023

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SCORCH: Improving structure-based virtual screening with machine learning classifiers, data augmentation, and uncertainty estimation.
Miles McGibbon, Sam Money-Kyrle, Vincent Blay, Douglas R Houston

J Adv Res· April 2023

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Modelling of Hepatitis E virus RNA-dependent RNA polymerase genotype 3 from a chronic patient and interaction analysis by molecular docking with Ribavirin.
Florencia Cancela, Santiago Rendon-Marin, Carolina Quintero-Gil, Douglas R Houston, Gediminas Gumbis

J Biomol Struct Dyn· February 2023

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Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes.
Lisa A Lansdon, Amanda Dickinson, Sydney Arlis, Huan Liu, Arman Hlas, Douglas W Houston

Am J Hum Genet· January 2023

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Correction: Vegetally localized Xenopus trim36 regulates cortical rotation and dorsal axis formation.
Tawny N Cuykendall, Douglas W Houston

Development· November 2022

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Comparison of ATP-binding pockets and discovery of homologous recombination inhibitors.
Vincent Blay, Saule Gailiunaite, Chih-Ying Lee, Hao-Yen Chang, Ted Hupp, Douglas R Houston

Bioorg Med Chem· September 2022

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Maternal Wnt11b regulates cortical rotation during Xenopus axis formation: analysis of maternal-effect wnt11b mutants.
Douglas W Houston, Karen L Elliott, Kelsey Coppenrath, Marcin Wlizla, Marko E Horb

Development· September 2022

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Evidence that nuclear receptors are related to terpene synthases.
Douglas R Houston, Jane G Hanna, J Constance Lathe, Stephen G Hillier, Richard Lathe

J Mol Endocrinol· March 2022

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A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry and .
Catherine Adam, Thomas L Bray, Ana M Pérez-López, Ee Hong Tan, Belén Rubio-Ruiz, Douglas R Houston

J Med Chem· January 2022

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Correction: Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme.
Christopher J Harding, Emmajay Sutherland, Jane G Hanna, Douglas R Houston, Clarissa M Czekster

RSC Chem Biol· June 2021

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Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme.
Christopher J Harding, Emmajay Sutherland, Jane G Hanna, Douglas R Houston, Clarissa M Czekster

RSC Chem Biol· January 2021

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PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation.
Jeanette A Johansson, Kerrie L Marie, Yuting Lu, Alessandro Brombin, Cristina Santoriello, Douglas R Houston

Dev Cell· August 2020

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Design of drug-like hepsin inhibitors against prostate cancer and kidney stones.
Vincent Blay, Mu-Chun Li, Sunita P Ho, Mashall L Stoller, Hsing-Pang Hsieh, Douglas R Houston

Acta Pharm Sin B· July 2020

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Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface.
Monikaben Padariya, Umesh Kalathiya, Douglas R Houston, Javier Antonio Alfaro

Cancers (Basel)· March 2020

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Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1.
Umesh Kalathiya, Monikaben Padariya, Kamila Pawlicka, Chandra S Verma, Douglas Houston

Int J Mol Sci· November 2019

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Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity.
Alex A Makarov, Juan Zou, Douglas R Houston, Christos Spanos, Alexandra S Solovyova

Nat Commun· July 2019

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Topologically correct central projections of tetrapod inner ear afferents require Fzd3.
Jeremy S Duncan, Bernd Fritzsch, Douglas W Houston, Elizabeth M Ketchum, Jennifer Kersigo

Sci Rep· July 2019

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