Publications by authors named "Duke Geem"

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A Myeloid Lineage Signifying Anti-tumor Necrosis Factor Resistance in Crohn's Disease.
Sachith Munasinghe, Duke Geem, Kodhai Duraiarasan, Sushma C Maddipatla, Shanta Murthy

Cell Mol Gastroenterol Hepatol· December 2025

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Altered inflammatory mucosal signatures within their spatial and cellular context during active ileal Crohn's disease.
Vasantha L Kolachala, Sushma Chowdary Maddipatla, Shanta Murthy, Yeonjoo Hwang, Anne F Dodd, Duke Geem

JCI Insight· March 2025

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Progression of Pediatric Crohn's Disease Is Associated With Anti-Tumor Necrosis Factor Timing and Body Mass Index Z-Score Normalization.
Duke Geem, David Hercules, Ranjit S Pelia, Suresh Venkateswaran, Anne Griffiths

Clin Gastroenterol Hepatol· February 2024

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Persistent Inflammation of the Rectum in Perianal Fistulizing Crohn's Disease Is Associated With Goblet Cell Function.
Savannah Washburn, Sushma C Maddipatla, Shanta Murthy, Anne Dodd, Ranjit S Pelia, Duke Geem

Gastro Hep Adv· September 2023

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Characterization of Intestinal Mesenchymal Stromal Cells From Patients With Inflammatory Bowel Disease for Autologous Cell Therapy.
Murugadas Anbazhagan, Duke Geem, Suresh Venkateswaran, Ranjit Pelia, Vasantha L Kolachala

Stem Cells Transl Med· March 2023

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Assessing Cellular and Transcriptional Diversity of Ileal Mucosa Among Treatment-Naïve and Treated Crohn's Disease.
Sushma Chowdary Maddipatla, Vasantha L Kolachala, Suresh Venkateswaran, Anne F Dodd, Ranjit Singh Pelia, Duke Geem

Inflamm Bowel Dis· February 2023

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Resolution of recurrent pediatric acute liver failure with liver transplantation in a patient with NBAS mutation.
Duke Geem, Wenxiao Jiang, Heather B Rytting, Shanmuganathan Chandrakasan, Anand Salem

Pediatr Transplant· November 2021

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Undiagnosed Metachromatic Leukodystrophy Presenting as Severe Gastrointestinal Bleeding and Cholestasis from Hemobilia.
James P Stevens, Janani Dakshinamoorthy, Anne Elizabeth Gill, Paul Parker, Duke Geem

JPGN Rep· November 2021

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It Takes Two to Make It Right: Dual Biologic and Small Molecule Therapy for Treatment-Refractory Pediatric Inflammatory Bowel Disease.
Duke Geem, Subra Kugathasan

Inflamm Bowel Dis· July 2021

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Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3 Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis.
Hirohito Abo, Kyle L Flannigan, Duke Geem, Vu L Ngo, Akihito Harusato

Front Immunol· September 2020

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Effects of Second-Hand Smoke on Pancreatitis in Children.
Cortney R Ballengee, Peter Brooks, Traci Leong, Duke Geem, A Jay Freeman

Pancreas· February 2020

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A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage.
Vu L Ngo, Hirohito Abo, Estera Maxim, Akihito Harusato, Duke Geem

Proc Natl Acad Sci U S A· May 2018

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Macrophage Isolation from the Mouse Small and Large Intestine.
Akihito Harusato, Duke Geem, Timothy L Denning

Methods Mol Biol· December 2017

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Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment.
Duke Geem, Vu Ngo, Akihito Harusato, Benoit Chassaing, Andrew T Gewirtz

Cell Mol Gastroenterol Hepatol· May 2016

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Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage.
Oscar Medina-Contreras, Akihito Harusato, Hikaru Nishio, Kyle L Flannigan, Vu Ngo, Duke Geem

J Immunol· January 2016

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Small intestinal intraepithelial TCRγδ+ T lymphocytes are present in the premature intestine but selectively reduced in surgical necrotizing enterocolitis.
Jörn-Hendrik Weitkamp, Michael J Rosen, Zhiguo Zhao, Tatsuki Koyama, Duke Geem

PLoS One· October 2015

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Intestinal Antigen-Presenting Cells: Key Regulators of Immune Homeostasis and Inflammation.
Kyle L Flannigan, Duke Geem, Akihito Harusato, Timothy L Denning

Am J Pathol· July 2015

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Harnessing regulatory T cells for the treatment of inflammatory bowel disease.
Duke Geem, Akihito Harusato, Kyle Flannigan, Timothy L Denning

Inflamm Bowel Dis· June 2015

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Phenotypic and functional profiling of mouse intestinal antigen presenting cells.
Akihito Harusato, Kyle L Flannigan, Duke Geem, Timothy L Denning

J Immunol Methods· June 2015

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Fab'-bearing siRNA TNFα-loaded nanoparticles targeted to colonic macrophages offer an effective therapy for experimental colitis.
Hamed Laroui, Emilie Viennois, Bo Xiao, Brandon S B Canup, Duke Geem

J Control Release· July 2014

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Specific microbiota-induced intestinal Th17 differentiation requires MHC class II but not GALT and mesenteric lymph nodes.
Duke Geem, Oscar Medina-Contreras, Michelle McBride, Rodney D Newberry, Pandelakis A Koni

J Immunol· July 2014

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Targeting intestinal inflammation with CD98 siRNA/PEI-loaded nanoparticles.
Hamed Laroui, Duke Geem, Bo Xiao, Emilie Viennois, Poonam Rakhya

Mol Ther· January 2014

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T lymphocytes and vascular inflammation contribute to stress-dependent hypertension.
Paul J Marvar, Antony Vinh, Salim Thabet, Heinrich E Lob, Duke Geem

Biol Psychiatry· May 2012

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Isolation and characterization of dendritic cells and macrophages from the mouse intestine.
Duke Geem, Oscar Medina-Contreras, Wooki Kim, Clifton S Huang, Timothy L Denning

J Vis Exp· May 2012

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CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice.
Oscar Medina-Contreras, Duke Geem, Oskar Laur, Ifor R Williams, Sergio A Lira

J Clin Invest· December 2011

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