Publications by authors named "Duncan B Richards"

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Health outcomes 3 months and 6 months after molnupiravir treatment for COVID-19 for people at higher risk in the community (PANORAMIC): a randomised controlled trial.
Victoria Harris, Jane Holmes, Oghenekome Gbinigie-Thompson, Najib M Rahman, Duncan B Richards

Lancet Infect Dis· January 2025

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Developing generic clinical trial animated explainer videos in the UK: results of a survey and case study.
Clare Calvert, Vicki S Barber, Duncan Appelbe, Kirsty Sprange, Claire Nollett, Duncan B Richards

Trials· January 2025

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Cost-utility analysis of molnupiravir for high-risk, community-based adults with COVID-19: an economic evaluation of the PANORAMIC trial.
May Ee Png, Victoria Harris, Jenna Grabey, Nigel D Hart, Bhautesh D Jani, Duncan B Richards

Br J Gen Pract· August 2024

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Use of oxygen-loaded nanobubbles to improve tissue oxygenation: Bone-relevant mechanisms of action and effects on osteoclast differentiation.
Helen J Knowles, Alexandra Vasilyeva, Mihir Sheth, Oliver Pattinson, Jonathan May, Duncan B Richards

Biomaterials· March 2024

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Current usage of explainer animations in trials: a survey of the UKCRC registered clinical trial units in the UK.
Vicki S Barber, Clare Calvert, Duncan Appelbe, Kirsty Sprange, Claire Nollett, Duncan B Richards

Trials· March 2024

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Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients.
Joseph F Standing, Laura Buggiotti, Jose Afonso Guerra-Assuncao, Maximillian Woodall, Samuel Ellis, Duncan B Richards

Nat Commun· February 2024

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Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial.
Christopher C Butler, F D Richard Hobbs, Oghenekome A Gbinigie, Najib M Rahman, Gail Hayward, Duncan B Richards

Lancet· January 2023

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Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.
Hisham Ziauddeen, Liam J Nestor, Naresh Subramaniam, Chris Dodds, Pradeep J Nathan, Duncan B Richards

Neuropsychopharmacology· March 2018

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A randomized, double-blind, placebo-controlled trial of camicinal in Parkinson's disease.
Sarah L Marrinan, Tal Otiker, Lakshmi S Vasist, Rachel A Gibson, Bhopinder K Sarai, Duncan B Richards

Mov Disord· February 2018

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Repeat doses of antibody to serum amyloid P component clear amyloid deposits in patients with systemic amyloidosis.
Duncan B Richards, Louise M Cookson, Sharon V Barton, Lia Liefaard, Thirusha Lane

Sci Transl Med· January 2018

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Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.
Hisham Ziauddeen, Liam J Nestor, Naresh Subramaniam, Chris Dodds, Pradeep J Nathan, Duncan B Richards

Neuropsychopharmacology· October 2016

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The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial.
Marianne J Chapman, Adam M Deane, Stephanie L O'Connor, Nam Q Nguyen, Robert J L Fraser, Duncan B Richards

Crit Care· August 2016

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The pharmacodynamics, safety and pharmacokinetics of single doses of the motilin agonist, camicinal, in type 1 diabetes mellitus with slow gastric emptying.
Per M Hellström, Jan Tack, Lakshmi Vasist Johnson, Kimberley Hacquoil, Matthew E Barton, Duncan B Richards

Br J Pharmacol· June 2016

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Therapeutic Clearance of Amyloid by Antibodies to Serum Amyloid P Component.
Duncan B Richards, Louise M Cookson, Alienor C Berges, Sharon V Barton, Thirusha Lane

N Engl J Med· September 2015

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The effects of alcohol on the pharmacokinetics and pharmacodynamics of the selective mu-opioid receptor antagonist GSK1521498 in healthy subjects.
Hisham Ziauddeen, Pradeep J Nathan, Chris Dodds, Kay Maltby, Sam R Miller, Duncan B Richards

J Clin Pharmacol· October 2013

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Effects of mu opioid receptor antagonism on cognition in obese binge-eating individuals.
Samuel R Chamberlain, Karin Mogg, Brendan P Bradley, Annelize Koch, Chris M Dodds, Duncan B Richards

Psychopharmacology (Berl)· December 2012

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Multiple-dose safety, pharmacokinetics, and pharmacodynamics of the μ-opioid receptor inverse agonist GSK1521498.
Pradeep J Nathan, Mark A Bush, Wenli X Tao, Annelize Koch, Kirsty M Davies, Duncan B Richards

J Clin Pharmacol· October 2012

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Opioid receptor modulation of hedonic taste preference and food intake: a single-dose safety, pharmacokinetic, and pharmacodynamic investigation with GSK1521498, a novel μ-opioid receptor inverse agonist.
Pradeep J Nathan, Barry V O'Neill, Mark A Bush, Annelize Koch, Wenli X Tao, Duncan B Richards

J Clin Pharmacol· April 2012

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Effects of multiple doses of ambrisentan on the pharmacokinetics of a single dose of digoxin in healthy volunteers.
Duncan B Richards, Rebecca Spence, Arun Mandagere, Linda S Henderson, Mindy H Magee

J Clin Pharmacol· January 2011

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Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial.
Duncan B Richards, Philippe Bareille, Emma L Lindo, Dean Quinn, Stuart N Farrow

Respir Med· May 2010

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Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
Duncan B Richards, Gennyne A Walker, Arun Mandagere, Mindy H Magee, Linda S Henderson

J Clin Pharmacol· June 2009

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