Publications by authors named "Duncan B Sparrow"

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Maternal Anaemia and Congenital Heart Disease in Offspring: A Case-Control Study Using Linked Electronic Health Records in the United Kingdom.
Manisha Nair, Cynthia W Drakesmith, Margaret Smith, Clare R Bankhead, Duncan B Sparrow

BJOG· July 2025

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Insights into the Role of a Cardiomyopathy-Causing Genetic Variant in .
Sophie Broadway-Stringer, He Jiang, Kirsty Wadmore, Charlotte Hooper, Gillian Douglas, Duncan B Sparrow

Cells· February 2023

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Myhre syndrome is caused by dominant-negative dysregulation of SMAD4 and other co-factors.
Dimuthu Alankarage, Annabelle Enriquez, Robert D Steiner, Cathy Raggio, Megan Higgins, Duncan B Sparrow

Differentiation· November 2022

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Better communication between experts is needed to solve the environmental origins of birth defects.
Duncan B Sparrow

Bioessays· February 2022

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Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects.
Jacinta I Kalisch-Smith, Emily C Morris, Mary A A Strevens, Andia N Redpath, Kostantinos Klaourakis, Duncan B Sparrow

Front Genet· January 2022

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The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition.
Emanuele Azzoni, Vincent Frontera, Giorgio Anselmi, Christina Rode, Chela James, Duncan B Sparrow

Cell Rep· December 2021

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Maternal iron deficiency perturbs embryonic cardiovascular development in mice.
Jacinta I Kalisch-Smith, Nikita Ved, Dorota Szumska, Jacob Munro, Michael Troup, Duncan B Sparrow

Nat Commun· June 2021

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Functional analysis of a gene-edited mouse model to gain insights into the disease mechanisms of a titin missense variant.
He Jiang, Charlotte Hooper, Matthew Kelly, Violetta Steeples, Jillian N Simon, Duncan B Sparrow

Basic Res Cardiol· February 2021

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Heterozygous loss of WBP11 function causes multiple congenital defects in humans and mice.
Ella M M A Martin, Annabelle Enriquez, Duncan B Sparrow, David T Humphreys, Aideen M McInerney-Leo

Hum Mol Genet· December 2020

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Environmental Risk Factors for Congenital Heart Disease.
Jacinta Isabelle Kalisch-Smith, Nikita Ved, Duncan Burnaby Sparrow

Cold Spring Harb Perspect Biol· March 2020

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Functional genomics and gene-environment interaction highlight the complexity of congenital heart disease caused by Notch pathway variants.
Gavin Chapman, Julie L M Moreau, Eddie I P, Justin O Szot, Kavitha R Iyer, Duncan B Sparrow

Hum Mol Genet· March 2020

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Tamoxifen administration in pregnant mice can be deleterious to both mother and embryo.
Nikita Ved, Angela Curran, Frances Mary Ashcroft, Duncan Burnaby Sparrow

Lab Anim· December 2019

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Gene-environment interaction impacts on heart development and embryo survival.
Julie L M Moreau, Scott Kesteven, Ella M M A Martin, Kin S Lau, Michelle X Yam, Duncan B Sparrow

Development· February 2019

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A Screening Approach to Identify Clinically Actionable Variants Causing Congenital Heart Disease in Exome Data.
Justin O Szot, Hartmut Cuny, Gillian M Blue, David T Humphreys, Eddie Ip, Duncan B Sparrow

Circ Genom Precis Med· March 2018

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NAD Deficiency, Congenital Malformations, and Niacin Supplementation.
Hongjun Shi, Annabelle Enriquez, Melissa Rapadas, Ella M M A Martin, Roni Wang, Duncan B Sparrow

N Engl J Med· August 2017

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Gestational stress induces the unfolded protein response, resulting in heart defects.
Hongjun Shi, Victoria C O'Reilly, Julie L M Moreau, Therese R Bewes, Michelle X Yam, Duncan B Sparrow

Development· July 2016

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Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling.
Lorine J Wilkinson, Cailda S Neal, Reetu R Singh, Duncan B Sparrow, Nyoman D Kurniawan

Kidney Int· May 2015

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Compound heterozygous mutations in RIPPLY2 associated with vertebral segmentation defects.
Aideen M McInerney-Leo, Duncan B Sparrow, Jessica E Harris, Brooke B Gardiner, Mhairi S Marshall

Hum Mol Genet· March 2015

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Cited2 is required in trophoblasts for correct placental capillary patterning.
Julie L M Moreau, Stanley T Artap, Hongjun Shi, Gavin Chapman, Gustavo Leone, Duncan B Sparrow

Dev Biol· August 2014

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Gene-environment interaction demonstrates the vulnerability of the embryonic heart.
Victoria C O'Reilly, Kylie Lopes Floro, Hongjun Shi, Bogdan E Chapman, Jost I Preis, Duncan B Sparrow

Dev Biol· July 2014

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Mutation of HES7 in a large extended family with spondylocostal dysostosis and dextrocardia with situs inversus.
Duncan B Sparrow, Eissa Ali Faqeih, Bahauddin Sallout, Abdulrahman Alswaid, Faroug Ababneh

Am J Med Genet A· September 2013

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Autosomal dominant spondylocostal dysostosis is caused by mutation in TBX6.
Duncan B Sparrow, Aideen McInerney-Leo, Zoran S Gucev, Brooke Gardiner, Mhairi Marshall

Hum Mol Genet· April 2013

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A mechanism for gene-environment interaction in the etiology of congenital scoliosis.
Duncan B Sparrow, Gavin Chapman, Allanceson J Smith, Muhammad Z Mattar, Joelene A Major

Cell· April 2012

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Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.
Mauro W Costa, Stella Lee, Milena B Furtado, Li Xin, Duncan B Sparrow

PLoS One· February 2012

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The mouse notches up another success: understanding the causes of human vertebral malformation.
Duncan B Sparrow, Gavin Chapman, Sally L Dunwoodie

Mamm Genome· August 2011

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