Publications by authors named "Duska Separovic"

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Controlling Immunoregulatory Cell Activity for Effective Photodynamic Therapy of Cancer.
Mladen Korbelik, Zdzislaw M Szulc, Alicja Bielawska, Duska Separovic

Methods Mol Biol· May 2022

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Racial Disparities in the Molecular Landscape of Cancer.
Elisabeth I Heath, Filipa Lynce, Joanne Xiu, Angela Ellerbrock, Sandeep K Reddy, Duska Separovic

Anticancer Res· April 2018

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Altered Levels of Serum Ceramide, Sphingosine and Sphingomyelin Are Associated with Colorectal Cancer: A Retrospective Pilot Study.
Duska Separovic, Anthony F Shields, Philip A Philip, Jacek Bielawski, Alicja Bielawska

Anticancer Res· March 2017

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Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.
Nithin B Boppana, Jacqueline M Kraveka, Mehrdad Rahmaniyan, L I Li, Alicja Bielawska, Duska Separovic

Anticancer Res· February 2017

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Interaction of acid ceramidase inhibitor LCL521 with tumor response to photodynamic therapy and photodynamic therapy-generated vaccine.
Mladen Korbelik, Judit Banáth, Wei Zhang, Kyi Min Saw, Zdzislaw M Szulc, Duska Separovic

Int J Cancer· September 2016

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Enhanced apoptotic cancer cell killing after Foscan photodynamic therapy combined with fenretinide via de novo sphingolipid biosynthesis pathway.
Nithin B Boppana, Jeremy S DeLor, Eric Van Buren, Alicja Bielawska, Jacek Bielawski, Duska Separovic

J Photochem Photobiol B· June 2016

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Enhanced killing of SCC17B human head and neck squamous cell carcinoma cells after photodynamic therapy plus fenretinide via the de novo sphingolipid biosynthesis pathway and apoptosis.
Nithin B Boppana, Ursula Stochaj, Mohamed Kodiha, Alicja Bielawska, Jacek Bielawski, Duska Separovic

Int J Oncol· May 2015

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C6-pyridinium ceramide sensitizes SCC17B human head and neck squamous cell carcinoma cells to photodynamic therapy.
Nithin B Boppana, Ursula Stochaj, Mohamed Kodiha, Alicja Bielawska, Jacek Bielawski, Duska Separovic

J Photochem Photobiol B· February 2015

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Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization.
Nithin B Boppana, Mohamed Kodiha, Ursula Stochaj, Ho-sheng Lin, Adriana Haimovitz-Friedman, Duska Separovic

Photochem Photobiol Sci· November 2014

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Ceramide and sphingosine-1-phosphate act as photodynamic therapy-elicited damage-associated molecular patterns: cell surface exposure.
Mladen Korbelik, Judit Banáth, Jinghai Sun, Daniel Canals, Yusuf A Hannun, Duska Separovic

Int Immunopharmacol· June 2014

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Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.
Duska Separovic, Paul Breen, Nithin B Boppana, Eric Van Buren, Nicholas Joseph

Int J Oncol· December 2013

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Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors.
Mladen Korbelik, Wei Zhang, Kyi Min Saw, Zdzislaw M Szulc, Alicja Bielawska, Duska Separovic

J Photochem Photobiol B· September 2013

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Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells.
Paul Breen, Nicholas Joseph, Kyle Thompson, Jacqueline M Kraveka, Tatyana I Gudz, Duska Separovic

Anticancer Res· January 2013

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siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.
Duska Separovic, Paul Breen, Nicholas Joseph, Jacek Bielawski, Jason S Pierce

Anticancer Res· July 2012

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Monitoring ceramide and sphingosine-1-phosphate levels in cancer cells and macrophages from tumours treated by photodynamic therapy.
Mladen Korbelik, Wei Zhang, Duska Separovic

Photochem Photobiol Sci· May 2012

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Guidelines for the use and interpretation of assays for monitoring autophagy.
Daniel J Klionsky, Fabio C Abdalla, Hagai Abeliovich, Robert T Abraham, Abraham Acevedo-Arozena, Duska Separovic

Autophagy· April 2012

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Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.
Duska Separovic, Paul Breen, Nicholas Joseph, Jacek Bielawski, Jason S Pierce

Anticancer Res· March 2012

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Amplification of cancer cell apoptosis in photodynamic therapy-treated tumors by adjuvant ceramide analog LCL29.
Mladen Korbelik, Wei Zhang, Duska Separovic

Lasers Surg Med· September 2011

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C16-Ceramide Analog Combined with Pc 4 Photodynamic Therapy Evokes Enhanced Total Ceramide Accumulation, Promotion of DEVDase Activation in the Absence of Apoptosis, and Augmented Overall Cell Killing.
Duska Separovic, Ziad H Saad, Ethan A Edwin, Jacek Bielawski, Jason S Pierce

J Lipids· July 2011

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Combining anticancer agents photodynamic therapy and LCL85 leads to distinct changes in the sphingolipid profile, autophagy, caspase-3 activation in the absence of cell death, and long-term sensitization.
Duska Separovic, Nicholas Joseph, Paul Breen, Jacek Bielawski, Jason S Pierce

Biochem Biophys Res Commun· June 2011

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Increased ceramide accumulation correlates with downregulation of the autophagy protein ATG-7 in MCF-7 cells sensitized to photodamage.
Duska Separovic, Ameeta Kelekar, Arun K Nayak, Adi L Tarca, Kentaro Hanada

Arch Biochem Biophys· February 2010

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Suppression of sphingomyelin synthase 1 by small interference RNA is associated with enhanced ceramide production and apoptosis after photodamage.
Duska Separovic, Louie Semaan, Adi L Tarca, Ma'In Yehya Awad Maitah, Kentaro Hanada

Exp Cell Res· May 2008

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Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage.
Duska Separovic, Kentaro Hanada, Ma'In Yehya Awad Maitah, Biserka Nagy, Ivan Hang

Biochem Biophys Res Commun· June 2007

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Ceramide response post-photodamage is absent after treatment with HA14-1.
Duska Separovic, Shouye Wang, Ma'In Yehya Awad Maitah, Kentaro Hanada, David Kessel

Biochem Biophys Res Commun· June 2006

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A role for manganese superoxide dismutase in apoptosis after photosensitization.
Vladislav Dolgachev, Larry W Oberley, Ting-Ting Huang, Janice M Kraniak, Michael A Tainsky, Duska Separovic

Biochem Biophys Res Commun· July 2005

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