Publications by authors named "Dwayne G Stupack"

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A non-apoptotic caspase-8-meteorin pathway in hepatocytes promotes MASH fibrosis.
Xiaobo Wang, Mary P Moore, Hongxue Shi, Yang Xiao, Jiayu Zhang, Dwayne G Stupack

Nat Metab· October 2025

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Ovarian Tumor FAK Inhibition Releases Omega-3 Fatty Acids Stimulating GATA6 Peritoneal Macrophage CXCL13 Production Enhancing Immunotherapy.
Xiao Lei Chen, Kevin M Tharp, Marjaana Ojalill, Duygu Ozmadenci, Antonia Boyer, Dwayne G Stupack

bioRxiv· September 2025

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Inducible FAK loss but not FAK inhibition in endothelial cells of PYK2-null mice activates p53 tumor suppressor to prevent tumor growth.
Xiao Lei Chen, Marjaana Ojalill, Christine Jean, Isabelle Tancioni, Shulin Jiang, Dwayne G Stupack

Mol Biol Cell· June 2025

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Nuclear Focal Adhesion Kinase Protects against Cisplatin Stress in Ovarian Carcinoma.
Yichi Zhang, Marjaana Ojalill, Antonia Boyer, Xiao Lei Chen, Elise Tahon, Dwayne G Stupack

Cancer Res Commun· December 2024

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Inducible FAK Deletion but not FAK Inhibition in Endothelial Cells Activates p53 to Suppress Tumor Growth in PYK2-null Mice.
Xiao Lei Chen, Marjaana Ojalill, Christine Jean, Isabelle Tancioni, Shulin Jiang, Dwayne G Stupack

bioRxiv· November 2024

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Focal adhesion kinase signaling - tumor vulnerabilities and clinical opportunities.
David D Schlaepfer, Marjaana Ojalill, Dwayne G Stupack

J Cell Sci· July 2024

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Nonsense-mediated RNA decay: an emerging modulator of malignancy.
Kun Tan, Dwayne G Stupack, Miles F Wilkinson

Nat Rev Cancer· August 2022

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Tumor FAK orchestrates immunosuppression in ovarian cancer via the CD155/TIGIT axis.
Duygu Ozmadenci, Jayanth S Shankara Narayanan, Jacob Andrew, Marjaana Ojalill, Allison M Barrie, Dwayne G Stupack

Proc Natl Acad Sci U S A· April 2022

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Association of Copy Number Variation Signature and Survival in Patients With Serous Ovarian Cancer.
Ryon P Graf, Ramez Eskander, Leo Brueggeman, Dwayne G Stupack

JAMA Netw Open· June 2021

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Targeting FAK in anticancer combination therapies.
John C Dawson, Alan Serrels, Dwayne G Stupack, David D Schlaepfer, Margaret C Frame

Nat Rev Cancer· May 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Dwayne G Stupack

Autophagy· January 2021

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Retraction for Nasimuzzaman et al., "Hepatitis C Virus Stabilizes Hypoxia-Inducible Factor 1α and Stimulates the Synthesis of Vascular Endothelial Growth Factor".
Md Nasimuzzaman, Gulam Waris, David Mikolon, Dwayne G Stupack, Aleem Siddiqui

J Virol· September 2020

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Underlying Subwavelength Aperture Architecture Drives the Optical Properties of Microcavity Surface Plasmon Resonance Sensors.
Dragos Amarie, Nazanin Mosavian, Elijah L Waters, Dwayne G Stupack

Sensors (Basel)· August 2020

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Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors.
Joe R Delaney, Chandni B Patel, Jaidev Bapat, Christian M Jones, Maria Ramos-Zapatero, Dwayne G Stupack

PLoS Genet· January 2020

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CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism.
Ruifang Gao, Dan Li, Jing Xun, Wei Zhou, Jun Li, Dwayne G Stupack

Theranostics· October 2019

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Rgnef promotes ovarian tumor progression and confers protection from oxidative stress.
Elizabeth G Kleinschmidt, Nichol L G Miller, Duygu Ozmadenci, Isabelle Tancioni, Carlos Díaz Osterman, Dwayne G Stupack

Oncogene· September 2019

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FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy.
Carlos J Diaz Osterman, Duygu Ozmadenci, Elizabeth G Kleinschmidt, Kristin N Taylor, Allison M Barrie, Dwayne G Stupack

Elife· September 2019

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PFKFB4 Promotes Breast Cancer Metastasis via Induction of Hyaluronan Production in a p38-Dependent Manner.
Ruifang Gao, Yanhua Liu, Dan Li, Jing Xun, Wei Zhou, Dwayne G Stupack

Cell Physiol Biochem· December 2018

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Whole Genome Pathway Analysis Identifies an Association of Cadmium Response Gene Loss with Copy Number Variation in Mutant p53 Bearing Uterine Endometrial Carcinomas.
Joe Ryan Delaney, Dwayne G Stupack

PLoS One· August 2017

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Duodenal-Jejunal Flexure GI Stromal Tumor Frequently Heralds Somatic and Notch Pathway Mutations.
Adam M Burgoyne, Martina De Siena, Maha Alkhuziem, Chih-Min Tang, Benjamin Medina, Dwayne G Stupack

JCO Precis Oncol· August 2017

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Nelfinavir is effective against human cervical cancer cells in vivo: a potential treatment modality in resource-limited settings.
Mitzie-Ann Davis, Joe R Delaney, Chandni B Patel, Ryan Storgard, Dwayne G Stupack

Drug Des Devel Ther· May 2017

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Haploinsufficiency networks identify targetable patterns of allelic deficiency in low mutation ovarian cancer.
Joe Ryan Delaney, Chandni B Patel, Katelyn McCabe Willis, Mina Haghighiabyaneh, Joshua Axelrod, Dwayne G Stupack

Nat Commun· February 2017

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JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms.
Yan Zhang, Long Shen, Dwayne G Stupack, Nan Bai, Jing Xun

Oncotarget· May 2016

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A strategy to combine pathway-targeted low toxicity drugs in ovarian cancer.
Joe R Delaney, Chandni Patel, Katelyn E McCabe, Dan Lu, Mitzie-Ann Davis, Dwayne G Stupack

Oncotarget· October 2015

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Role of Hyaluronan and Glucose on 4-Methylumbelliferone-inhibited Cell Proliferation in Breast Carcinoma Cells.
Rongrong Wang, Wei Zhou, Juan Wang, Yanhua Liu, Yanan Chen, Dwayne G Stupack

Anticancer Res· September 2015

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