Publications by authors named "Dylan England"

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Identification of a Novel Linker Enabling the Bioconjugation of a Cyclic Dinucleotide for the STING Antibody-Drug Conjugate TAK-500.
Hong Myung Lee, Kojo Abdul-Hadi, Vicky A Appleman, David Cardin, Linlin Dong, Dylan England

Bioconjug Chem· November 2025

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A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo.
Stanley C Xie, Chia-Wei Tai, Craig J Morton, Liting Ma, Shih-Chung Huang, Dylan England

PLoS Pathog· December 2024

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A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models.
Eric S Lightcap, Pengfei Yu, Stephen Grossman, Keli Song, Mithun Khattar, Dylan England

Sci Transl Med· September 2021

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Identification of Novel Carbocyclic Pyrimidine Cyclic Dinucleotide STING Agonists for Antitumor Immunotherapy Using Systemic Intravenous Route.
Stepan Vyskocil, David Cardin, Jeffrey Ciavarri, Joe Conlon, Courtney Cullis, Dylan England

J Med Chem· May 2021

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Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.
Steven P Langston, Stephen Grossman, Dylan England, Roushan Afroze, Neil Bence

J Med Chem· March 2021

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Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors.
Shih-Chung Huang, Sharmila Adhikari, James E Brownell, Emily F Calderwood, Jouhara Chouitar, Dylan B England

Bioorg Med Chem· October 2020

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Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.
Xingyue He, Jessica Riceberg, Teresa Soucy, Erik Koenig, James Minissale, Dylan England

Nat Chem Biol· November 2017

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Optimization of tetrahydronaphthalene inhibitors of Raf with selectivity over hERG.
Shih-Chung Huang, Sharmila Adhikari, Roushan Afroze, Katherine Brewer, Emily F Calderwood, Dylan B England

Bioorg Med Chem Lett· February 2016

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Histone deacetylase inhibitors derived from 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine and related heterocycles selective for the HDAC6 isoform.
Christopher Blackburn, Cynthia Barrett, Mable Brunson, Janice Chin, Dylan England

Bioorg Med Chem Lett· December 2014

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Design and optimization of potent and orally bioavailable tetrahydronaphthalene Raf inhibitors.
Alexandra E Gould, Ruth Adams, Sharmila Adhikari, Kathleen Aertgeerts, Roushan Afroze, Dylan B England

J Med Chem· March 2011

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Gold-catalyzed cycloisomerization of N-Propargylindole-2-carboxamides: application toward the synthesis of lavendamycin analogues.
Dylan B England, Albert Padwa

Org Lett· August 2008

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General access to the vinca and tacaman alkaloids using a Rh(II)-catalyzed cyclization/cycloaddition cascade.
Dylan B England, Albert Padwa

J Org Chem· April 2008

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The Rhodium(II) Carbenoid Cyclization-Cycloaddition Cascade of alpha-Diazo Dihydroindolinones for the Synthesis of Novel Azapolycyclic Ring Systems.
Dylan B England, James M Eagan, Gokce Merey, Olcay Anac, Albert Padwa

Tetrahedron· February 2008

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Substitution and cyclization reactions involving the quasi-antiaromatic 2H-indol-2-one ring system.
Dylan B England, Gokce Merey, Albert Padwa

Org Lett· September 2007

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Synthesis of (+/-)-3H-epivincamine via a Rh(II)-triggered cyclization/cycloaddition cascade.
Dylan B England, Albert Padwa

Org Lett· August 2007

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Synthesis of the western half of the lolicines and lolitrems.
Dylan B England, Jakob Magolan, Michael A Kerr

Org Lett· May 2006

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Synthesis and cross-coupling reactions of substituted 5-triflyloxyindoles.
Dylan B England, Michael A Kerr

J Org Chem· August 2005

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