Publications by authors named "Earl Gordon"

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Discovery of Potent STT3A/B Inhibitors and Assessment of Their Multipathogen Antiviral Potential and Safety.
Joseph E Pero, Elizabeth A Mueller, Ashley M Adams, Ramona S Adolph, Parikshit Bagchi, Earl Gordon

J Med Chem· August 2024

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PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits.
Feng Yi, Nirvan Rouzbeh, Kasper B Hansen, Yuelian Xu, Christopher M Fanger, Earl Gordon

Neuropharmacology· August 2020

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MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.
Robert A Volkmann, Christopher M Fanger, David R Anderson, Venkata Ramana Sirivolu, Kathy Paschetto, Earl Gordon

PLoS One· July 2016

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An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure.
Kevin S Thorneloe, Mui Cheung, Weike Bao, Hasan Alsaid, Stephen Lenhard, Earl Gordon

Sci Transl Med· November 2012

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Characterizing the role of Thr352 in the inhibition of the large conductance Ca2+-activated K+ channels by 1-[1-hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone.
Earl Gordon, Simon F Semus, Irina M Lozinskaya, Zuojun Lin, Xiaoping Xu

J Pharmacol Exp Ther· August 2010

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Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells.
Xiaoping Xu, Earl Gordon, Zuojun Lin, Irina M Lozinskaya, Yifeng Chen

Channels (Austin)· November 2009

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1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a potent and highly selective small molecule blocker of the large-conductance voltage-gated and calcium-dependent K+ channel.
Haoyu Zeng, Earl Gordon, Zuojun Lin, Irina M Lozinskaya, Robert N Willette

J Pharmacol Exp Ther· October 2008

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N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I.
Kevin S Thorneloe, Anthony C Sulpizio, Zuojun Lin, David J Figueroa, Angela K Clouse, Earl Gordon

J Pharmacol Exp Ther· August 2008

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2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels.
Earl Gordon, Irina M Lozinskaya, Zuojun Lin, Simon F Semus, Frank E Blaney

Mol Pharmacol· March 2008

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A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance.
Earl Gordon, Gianina Panaghie, Liyong Deng, Katharine J Bee, Torsten K Roepke

Cardiovasc Res· January 2008

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Acetic acid opens large-conductance Ca2+-activated K+ channels in guinea pig detrusor smooth muscle cells.
Srinivas Ghatta, Irina Lozinskaya, Zuojun Lin, Earl Gordon, Robert N Willette

Eur J Pharmacol· June 2007

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Influence of watershed system management on herbicide concentrations in Mississippi Delta oxbow lakes.
Robert M Zablotowicz, Martin A Locke, L Jason Krutz, Robert N Lerch, Richard E Lizotte, R Earl Gordon

Sci Total Environ· November 2006

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1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers.
Earl Gordon, Jaime-Lee Cohen, Robert Engel, Geoffrey W Abbott

Mol Pharmacol· March 2006

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Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies.
Earl Gordon, Torsten K Roepke, Geoffrey W Abbott

Biophys J· February 2006

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RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies.
Arun Anantharam, Anthony Lewis, Gianina Panaghie, Earl Gordon, Zoe A McCrossan

J Biol Chem· April 2003

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