Publications by authors named "Earle Bain"

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A Phase 3b Study for Management of Ocular Side Effects in Patients with Epidermal Growth Factor Receptor-Amplified Glioblastoma Receiving Depatuxizumab Mafodotin.
Colin J Vize, Stella K Kim, Tim Matthews, Marian Macsai, Ryan Merrell, Earle Bain

Ophthalmic Res· January 2024

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Depatuxizumab mafodotin in EGFR-amplified newly diagnosed glioblastoma: A phase III randomized clinical trial.
Andrew B Lassman, Stephanie L Pugh, Tony J C Wang, Kenneth Aldape, Hui K Gan, Earle E Bain

Neuro Oncol· February 2023

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EGFR mutations are associated with response to depatux-m in combination with temozolomide and result in a receptor that is hypersensitive to ligand.
Youri Hoogstrate, Wies Vallentgoed, Johan M Kros, Iris de Heer, Maurice de Wit, Earle Bain

Neurooncol Adv· December 2019

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Defining EGFR amplification status for clinical trial inclusion.
Pim J French, Marica Eoli, Juan Manuel Sepulveda, Iris de Heer, Johan M Kros, Earle Bain

Neuro Oncol· October 2019

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An Integrated Population Pharmacokinetic Model Versus Individual Models of Depatuxizumab Mafodotin, an Anti-EGFR Antibody Drug Conjugate, in Patients With Solid Tumors Likely to Overexpress EGFR.
Rajendar K Mittapalli, Sven Stodtmann, Anna Friedel, Rajeev M Menon, Earle Bain

J Clin Pharmacol· September 2019

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Efficacy and Safety of the α7-Nicotinic Acetylcholine Receptor Agonist ABT-126 in the Treatment of Cognitive Impairment Associated With Schizophrenia: Results From a Phase 2b Randomized Controlled Study in Smokers.
George M Haig, Deli Wang, Jun Zhao, Ahmed A Othman, Earle E Bain

J Clin Psychiatry· August 2019

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Epidermal growth factor receptor (EGFR) amplification rates observed in screening patients for randomized trials in glioblastoma.
Andrew B Lassman, Kenneth D Aldape, Peter J Ansell, Earle Bain, Walter J Curran

J Neurooncol· August 2019

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Safety and efficacy of depatuxizumab mafodotin + temozolomide in patients with EGFR-amplified, recurrent glioblastoma: results from an international phase I multicenter trial.
Andrew B Lassman, Martin J van den Bent, Hui K Gan, David A Reardon, Priya Kumthekar, Earle Bain

Neuro Oncol· January 2019

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Efficacy of depatuxizumab mafodotin (ABT-414) monotherapy in patients with EGFR-amplified, recurrent glioblastoma: results from a multi-center, international study.
Martin van den Bent, Hui K Gan, Andrew B Lassman, Priya Kumthekar, Ryan Merrell, Earle Bain

Cancer Chemother Pharmacol· December 2017

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Use of a Novel Artificial Intelligence Platform on Mobile Devices to Assess Dosing Compliance in a Phase 2 Clinical Trial in Subjects With Schizophrenia.
Earle E Bain, Laura Shafner, David P Walling, Ahmed A Othman, Christy Chuang-Stein

JMIR Mhealth Uhealth· February 2017

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Mitigating the Effects of Nonadherence in Clinical Trials.
Thomas M Shiovitz, Earle E Bain, David J McCann, Phil Skolnick, Thomas Laughren

J Clin Pharmacol· September 2016

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A Randomized Trial to Assess the Efficacy and Safety of ABT-126, a Selective α7 Nicotinic Acetylcholine Receptor Agonist, in the Treatment of Cognitive Impairment in Schizophrenia.
George M Haig, Earle E Bain, Weining Z Robieson, Jeffrey D Baker, Ahmed A Othman

Am J Psychiatry· August 2016

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A randomized trial of the efficacy and safety of the H3 antagonist ABT-288 in cognitive impairment associated with schizophrenia.
George M Haig, Earle Bain, Weining Robieson, Ahmed A Othman, Jeffrey Baker

Schizophr Bull· November 2014

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Mood stabilizer treatment increases serotonin type 1A receptor binding in bipolar depression.
Allison C Nugent, Paul J Carlson, Earle E Bain, William Eckelman, Peter Herscovitch

J Psychopharmacol· October 2013

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Reduced post-synaptic serotonin type 1A receptor binding in bipolar depression.
Allison C Nugent, Earle E Bain, Paul J Carlson, Alexander Neumeister, Omer Bonne

Eur Neuropsychopharmacol· August 2013

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A randomized, double-blind, placebo-controlled phase 2 study of α4β2 agonist ABT-894 in adults with ADHD.
Earle E Bain, Weining Robieson, Yili Pritchett, Tushar Garimella, Walid Abi-Saab

Neuropsychopharmacology· February 2013

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A randomized pilot study of the efficacy and safety of ABT-089, a novel α4β2 neuronal nicotinic receptor agonist, in adults with attention-deficit/hyperactivity disorder.
Earle E Bain, George Apostol, R Bart Sangal, Weining Z Robieson, Dawnelle L McNeill

J Clin Psychiatry· June 2012

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Sex differences in the neural correlates of autonomic arousal: a pilot PET study.
Allison C Nugent, Earle E Bain, Julian F Thayer, John J Sollers, Wayne C Drevets

Int J Psychophysiol· June 2011

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Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study.
Jonathan B Savitz, Allison C Nugent, Wendy Bogers, Jonathan P Roiser, Earle E Bain

Biol Psychiatry· February 2011

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Heart rate variability during motor and cognitive tasks in females with major depressive disorder.
Allison Carol Nugent, Earle Eugene Bain, Julian Francis Thayer, John James Sollers, Wayne Curtis Drevets

Psychiatry Res· January 2011

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D3 receptor target engagement in humans with ABT-925 using [11C](+)-PHNO PET.
Mark Day, Earle Bain, Gerard Marek, Mario Saltarelli, Gerard B Fox

Int J Neuropsychopharmacol· April 2010

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Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication.
Jonathan Savitz, Allison C Nugent, Wendy Bogers, Alice Liu, Rebecca Sills, Earle E Bain

Neuroimage· February 2010

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A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression.
M Kathleen Holmes, Kristine Erickson, David A Luckenbaugh, Wayne C Drevets, Earle E Bain

Bipolar Disord· November 2008

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Reduced posterior hippocampal volume in posttraumatic stress disorder.
Omer Bonne, Meena Vythilingam, Masatoshi Inagaki, Suzanne Wood, Alexander Neumeister, Earle E Bain

J Clin Psychiatry· July 2008

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Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder.
Kristine Erickson, Wayne C Drevets, Luke Clark, Dara M Cannon, Earle E Bain

Am J Psychiatry· November 2005

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