Publications by authors named "Ed Cleator"

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Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor.
Yong-Li Zhong, Ed Cleator, Zhijian Liu, Jianguo Yin, William J Morris

J Org Chem· April 2019

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A Synthesis of a Spirocyclic Macrocyclic Protease Inhibitor for the Treatment of Hepatitis C.
Cheol K Chung, Ed Cleator, Aaron M Dumas, Jacqueline D Hicks, Guy R Humphrey

Org Lett· March 2016

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Asymmetric synthesis of cis-2,5-disubstituted pyrrolidine, the core scaffold of β3-AR agonists.
Feng Xu, John Y L Chung, Jeffery C Moore, Zhuqing Liu, Naoki Yoshikawa, Ed Cleator

Org Lett· March 2013

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Total synthesis of (-)-nakadomarin A.
Andrew F Kyle, Pavol Jakubec, Dane M Cockfield, Ed Cleator, John Skidmore

Chem Commun (Camb)· September 2011

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Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual Orexin inhibitor Suvorexant (MK-4305).
Neil A Strotman, Carl A Baxter, Karel M J Brands, Ed Cleator, Shane W Krska

J Am Chem Soc· June 2011

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A novel approach to 3-methylindoles by a Heck/cyclization/isomerization process.
Carl A Baxter, Ed Cleator, Mahbub Alam, Antony J Davies, Adrian Goodyear

Org Lett· February 2010

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A mild and efficient one-pot synthesis of 2-aminated benzoxazoles and benzothiazoles.
Gavin W Stewart, Carl A Baxter, Ed Cleator, Faye J Sheen

J Org Chem· April 2009

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The synthesis of azadirachtin: a potent insect antifeedant.
Steven V Ley, Antonio Abad-Somovilla, James C Anderson, Carles Ayats, Rolf Bänteli, Ed Cleator

Chemistry· December 2008

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Total synthesis of five thapsigargins: guaianolide natural products exhibiting sub-nanomolar SERCA inhibition.
Stephen P Andrews, Matthew Ball, Frank Wierschem, Ed Cleator, Steven Oliver

Chemistry· September 2007

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Intramolecular cyclopropanation of unsaturated terminal epoxides and chlorohydrins.
David M Hodgson, Ying Kit Chung, Irene Nuzzo, Gloria Freixas, Krystyna K Kulikiewicz, Ed Cleator

J Am Chem Soc· April 2007

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Total synthesis of thapsigargin, a potent SERCA pump inhibitor.
Matthew Ball, Stephen P Andrews, Frank Wierschem, Ed Cleator, Martin D Smith

Org Lett· February 2007

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A concise total synthesis of (+)-okaramine C.
Peter R Hewitt, Ed Cleator, Steven V Ley

Org Biomol Chem· September 2004

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Synthesis of the thapsigargins.
Steven V Ley, Alessandra Antonello, Emily P Balskus, David T Booth, Søren B Christensen, Ed Cleator

Proc Natl Acad Sci U S A· August 2004

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Synthesis of (-)-gloeosporone, a fungal autoinhibitor of spore germination using a pi-allyltricarbonyliron lactone complex as a templating architecture for 1,7-diol construction.
Steven V Ley, Ed Cleator, Jürgen Harter, Christopher J Hollowood

Org Biomol Chem· October 2003

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A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo[2,3-b]indole skeleton, a building block for 10b-hydroxy-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4-diones.
Steven V Ley, Ed Cleator, Peter R Hewitt

Org Biomol Chem· October 2003

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