Publications by authors named "Edgar John"

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Sex-biased human thymic architecture guides T cell development through spatially defined niches.
Laura N Stankiewicz, Kevin Salim, Emily A Flaschner, Yu Xin Wang, John M Edgar

Dev Cell· January 2025

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Tracking the gene expression programs and clonal relationships that underlie mast, myeloid, and T lineage specification from stem cells.
Yale S Michaels, Matthew C Major, Becca Bonham-Carter, Jingqi Zhang, Tiam Heydari, John M Edgar

Cell Syst· December 2024

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Wiskott-Aldrich syndrome: a study of 577 patients defines the genotype as a biomarker for disease severity and survival.
Tanja C Vallée, Jannik S Glasmacher, Hannes Buchner, Peter D Arkwright, Uta Behrends, John David M Edgar, John B Ziegler

Blood· June 2024

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XLA and Recurrent Conjunctivitis: a Unique Association?
Vyanka Redenbaugh, Anne Sloan, Jacklyn Sui, John David Edgar, Tanya Coulter

J Clin Immunol· April 2023

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Sex biased human thymic architecture guides T cell development through spatially defined niches.
Laura N Stankiewicz, Kevin Salim, Emily A Flaschner, Yu Xin Wang, John M Edgar

bioRxiv· April 2023

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Influence of the drug deformation behaviour on the predictability of compressibility and compactibility of binary mixtures.
Isabell Wünsch, Jan Henrik Finke, Edgar John, Michael Juhnke, Arno Kwade

Int J Pharm· October 2022

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Tectonically-driven oxidant production in the hot biosphere.
Jordan Stone, John O Edgar, Jamie A Gould, Jon Telling

Nat Commun· August 2022

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DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells.
Yale S Michaels, John M Edgar, Matthew C Major, Elizabeth L Castle, Carla Zimmerman

Sci Adv· August 2022

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Evaluation of the Formulation Parameter-Dependent Redispersibility of API Nanoparticles from Fluid Bed Granules.
Martin Wewers, Jan Henrik Finke, Stefan Czyz, Bernard Van Eerdenbrugh, Edgar John

Pharmaceutics· August 2022

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Numerical modeling of the dissolution of drug nanocrystals and its application to industrial product development.
Bastian Bonhoeffer, Andreas Kordikowski, Edgar John, Michael Juhnke

ADMET DMPK· August 2022

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Prediction of the impact of lubrication on tablet compactibility.
Daniel Puckhaber, Jan Henrik Finke, Sarah David, Mauro Serratoni, Umair Zafar, Edgar John

Int J Pharm· April 2022

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1,2-Dehydropyrrolizidine Alkaloids: Their Potential as a Dietary Cause of Sporadic Motor Neuron Diseases.
John A Edgar, Russell J Molyneux, Steven M Colegate

Chem Res Toxicol· March 2022

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Multi-objective optimization reveals time- and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development.
John M Edgar, Yale S Michaels, Peter W Zandstra

NPJ Regen Med· January 2022

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Modifications of IL-6 by Hypochlorous Acids: Effects on Receptor Binding.
Lori I Robins, Erika K Keim, Deborah B Robins, John S Edgar, John S Meschke

ACS Omega· December 2021

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Simple Measurement of IgA Predicts Immunity and Mortality in Ataxia-Telangiectasia.
Stefan Zielen, Ruth Pia Duecker, Sandra Woelke, Helena Donath, Sharhzad Bakhtiar, John David M Edgar

J Clin Immunol· November 2021

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How can single particle compression and nanoindentation contribute to the understanding of pharmaceutical powder compression?
Isabell Wünsch, Stephanie Michel, Jan Henrik Finke, Edgar John, Michael Juhnke

Eur J Pharm Biopharm· August 2021

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The influence of particle size on the application of compression and compaction models for tableting.
Isabell Wünsch, Jan Henrik Finke, Edgar John, Michael Juhnke, Arno Kwade

Int J Pharm· April 2021

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Repeated isolation of an antibiotic-dependent and temperature-sensitive mutant of Pseudomonas aeruginosa from a cystic fibrosis patient.
Daniel J Wolter, Alison Scott, Catherine R Armbruster, Dale Whittington, John S Edgar

J Antimicrob Chemother· February 2021

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Linking Dietary Exposure to 1,2-Dehydropyrrolizidine Alkaloids with Cancers and Chemotherapy-Induced Pulmonary and Hepatic Veno-Occlusive Diseases.
John A Edgar, Russell J Molyneux, Steven M Colegate

J Agric Food Chem· June 2020

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Influence of Formulation Parameters on Redispersibility of Naproxen Nanoparticles from Granules Produced in a Fluidized Bed Process.
Martin Wewers, Stefan Czyz, Jan Henrik Finke, Edgar John, Bernard Van Eerdenbrugh

Pharmaceutics· April 2020

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Unexpected combination: DiGeorge syndrome and myeloperoxidase deficiency.
Simona Abraitytė, Elisabeth Kotsi, Lisa Anne Devlin, John David Moore Edgar

BMJ Case Rep· February 2020

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L-ascorbic acid and the evolution of multicellular eukaryotes.
John Alexander Edgar

J Theor Biol· September 2019

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Current clinical practice and challenges in the management of secondary immunodeficiency in hematological malignancies.
Il-Kang Na, Matthew Buckland, Carlo Agostini, John David M Edgar, Vanda Friman

Eur J Haematol· June 2019

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A Mathematical Approach to Consider Solid Compressibility in the Compression of Pharmaceutical Powders.
Isabell Wünsch, Jan Henrik Finke, Edgar John, Michael Juhnke, Arno Kwade

Pharmaceutics· March 2019

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Prescribing Immunoglobulin Replacement Therapy for Patients with Non-classical and Secondary Antibody Deficiency: an Analysis of the Practice of Clinical Immunologists in the UK and Republic of Ireland.
John David M Edgar, Alex G Richter, Aarnoud P Huissoon, Dinakantha S Kumararatne, Helen E Baxendale

J Clin Immunol· February 2018

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