Publications by authors named "Edgardo Poskus"

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Novel Flow Cytometric Immunoassay for Detection of Proinsulin Autoantibodies in Diabetes Mellitus Employing a Recombinant Autoantigen Expressed in .
Adriana Victoria Sabljic, Silvina Sonia Bombicino, Juan Ignacio Marfía, Luciano Lucas Guerra, Alberto Penas Steinhardt, Edgardo Poskus

Front Immunol· October 2021

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Prokaryotic expression and characterization of the heterodimeric construction of ZnT8 and its application for autoantibodies detection in diabetes mellitus.
Natalia I Faccinetti, Luciano L Guerra, Adriana V Sabljic, Silvina S Bombicino, Bruno D Rovitto, Edgardo Poskus

Microb Cell Fact· November 2017

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Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application.
Luciano Lucas Guerra, Natalia Inés Faccinetti, Aldana Trabucchi, Bruno David Rovitto, Adriana Victoria Sabljic, Edgardo Poskus

BMC Biotechnol· November 2016

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Use of cross-reactivity immunoassay to orient insulin replacement in diabetic patients with high levels of insulin antibodies.
Alejandro Cardoso Landaburu, María Pomares, Alfredo Avalos, Silvia Lapertosa, Gustavo Frechtel, Edgardo Poskus

MethodsX· September 2016

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Biochemical, biophysical, and functional properties of ICA512/IA-2 RESP18 homology domain.
Laura Sosa, Juha M Torkko, María E Primo, Ramiro E Llovera, Pamela L Toledo, Edgardo Poskus

Biochim Biophys Acta· May 2016

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Characterization of zinc transporter 8 (ZnT8) antibodies in autoimmune diabetic patients from Argentinian population using monomeric, homodimeric, and heterodimeric ZnT8 antigen variants.
Natalia I Faccinetti, Luciano L Guerra, Alberto Penas Steinhardt, Ruben F Iacono, Gustavo D Frechtel, Edgardo Poskus

Eur J Endocrinol· February 2016

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X-ray structure of the mature ectodomain of phogrin.
Martín E Noguera, María E Primo, Jean Jakoncic, Edgardo Poskus, Michele Solimena

J Struct Funct Genomics· March 2015

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Characterization of insulin antibodies by Surface Plasmon Resonance in two clinical cases: brittle diabetes and insulin autoimmune syndrome.
Aldana Trabucchi, Ruben F Iacono, Luciano L Guerra, Natalia I Faccinetti, Andrea G Krochik, Edgardo Poskus

PLoS One· August 2014

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Flow cytometric microsphere-based immunoassay as a novel non-radiometric method for the detection of glutamic acid decarboxylase autoantibodies in type 1 diabetes mellitus.
Luciano L Guerra, Aldana Trabucchi, Natalia I Faccinetti, Ruben F Iacono, Daniela B Ureta, Edgardo Poskus

Analyst· June 2014

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Biophysical characterization of the membrane-proximal ectodomain of the receptor-type protein-tyrosine phosphatase phogrin.
Martin E Noguera, Maria E Primo, Laura N F Sosa, Valeria A Risso, Edgardo Poskus

Protein Pept Lett· September 2013

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Functional characterization of TLR4 +3725 G/C polymorphism and association with protection against overweight.
Alberto Penas-Steinhardt, Lucía Soledad Barcos, Fiorella Sabrina Belforte, Martha de Sereday, Jorge Vilariño, Edgardo Poskus

PLoS One· May 2013

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Surface plasmon resonance reveals a different pattern of proinsulin autoantibodies concentration and affinity in diabetic patients.
Aldana Trabucchi, Luciano L Guerra, Natalia I Faccinetti, Rubén F Iacono, Edgardo Poskus

PLoS One· July 2012

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Expression and characterization of human proinsulin fused to thioredoxin in Escherichia coli.
Aldana Trabucchi, Luciano Lucas Guerra, Natalia Inés Faccinetti, Ruben Francisco Iacono, Edgardo Poskus

Appl Microbiol Biotechnol· June 2012

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Protein-protein interactions in crystals of the human receptor-type protein tyrosine phosphatase ICA512 ectodomain.
María E Primo, Jean Jakoncic, Martín E Noguera, Valeria A Risso, Laura Sosa, Edgardo Poskus

PLoS One· April 2012

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Detection and characterization of ZnT8 autoantibodies could help to screen latent autoimmune diabetes in adult-onset patients with type 2 phenotype.
Aldana Trabucchi, Natalia I Faccinetti, Luciano L Guerra, Félix M Puchulu, Gustavo D Frechtel, Edgardo Poskus

Autoimmunity· March 2012

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Association of common variants in JAK2 gene with reduced risk of metabolic syndrome and related disorders.
Alberto Penas-Steinhardt, Mariana L Tellechea, Leonardo Gomez-Rosso, Fernando Brites, Gustavo D Frechtel, Edgardo Poskus

BMC Med Genet· December 2011

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The rs1801278 G>A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status.
María Silvia Pérez, Mariana L Tellechea, Florencia Aranguren, Mariano J Taverna, Ricardo G Rodríguez, Edgardo Poskus

Diabetes Res Clin Pract· September 2011

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Frequency of pancreatic beta-cell autoimmunity markers in patients with autoimmune thyroid disease.
María E Primo, Hugo Niepomniszcze, Edgardo Poskus, Monica S Sala, Silvia S Guaita

Medicina (B Aires)· January 2009

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Detection and immunochemical characterization of glutamic acid decarboxylase autoantibodies in patients with autoimmune diabetes mellitus.
Anabel Villalba, Rubén F Iacono, Silvina N Valdez, Edgardo Poskus

Autoimmunity· March 2008

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Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2.
María E Primo, Sebastián Klinke, Mauricio P Sica, Fernando A Goldbaum, Jean Jakoncic, Edgardo Poskus

J Biol Chem· February 2008

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Development of 2 alternative enzyme-linked immunosorbent assays for routine screening of glutamic acid decarboxylase autoantibodies.
Anabel Villalba, Silvina N Valdez, Rubén F Iacono, Edgardo Poskus

Clin Chim Acta· February 2007

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Expression and physicochemical characterization of an extracellular segment of the receptor protein tyrosine phosphatase IA-2.
María E Primo, Mauricio P Sica, Valeria A Risso, Edgardo Poskus, Mario R Ermácora

Biochim Biophys Acta· February 2006

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Single-tube test for autoantibodies to glutamic acid decarboxylase and proinsulin as first-line screening for autoimmunity in adult-onset diabetic patients.
Silvina N Valdez, Anabel Villalba, Ruben F Iacono, Edgardo Poskus

Clin Immunol· December 2004

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A radioligand-binding assay for detecting antibodies specific for proinsulin and insulin using 35S-proinsulin.
Silvina N Valdez, Rubén F Iacono, Anabel Villalba, Alejandro Cardoso Landaburu, Mario R Ermácora, Edgardo Poskus

J Immunol Methods· August 2003

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High-yield expression of properly folded insulinoma-associated protein intracellular domain (IA-2ic) in Escherichia coli.
Mauricio P Sica, María E Primo, Mario R Ermácora, Edgardo Poskus

Biotechnol Appl Biochem· June 2003

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