Publications by authors named "Edith C Glazer"

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Supramolecular self-assemblies of Ru(II) phototherapeutics: biological activity of micro- and nano-particles acting as reservoirs.
Jérôme Laisney, Sarah M Kriger, Dmytro Havrylyuk, Jason M Unrine, David K Heidary, Edith C Glazer

J Mater Chem B· December 2025

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Multifaceted Ru(II) arene systems for phototherapy display activity in lung cancer and melanoma.
Joseph Spiconardi, Dmytro Havrylyuk, Ge Shi, Alisher Talgatov, Colin G Cameron, Edith C Glazer

Photochem Photobiol· October 2025

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Photo-ejected ligands hyperpolarized by parahydrogen in reversible exchange.
Emily E Brown, Rielly J Harrison, Dmytro Havrylyuk, Stephen J McBride, Edith C Glazer

Chem Commun (Camb)· March 2025

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Photodynamic therapy photosensitizers and photoactivated chemotherapeutics exhibit distinct bioenergetic profiles to impact ATP metabolism.
Richard J Mitchell, Dmytro Havrylyuk, Austin C Hachey, David K Heidary, Edith C Glazer

Chem Sci· January 2025

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The Impact of Inorganic Systems and Photoactive Metal Compounds on Cytochrome P450 Enzymes and Metabolism: From Induction to Inhibition.
Dmytro Havrylyuk, David K Heidary, Edith C Glazer

Biomolecules· April 2024

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Triarylphosphine-Coordinated Bipyridyl Ru(II) Complexes Induce Mitochondrial Dysfunction.
Richard J Mitchell, Anitha S Gowda, Alexander G Olivelli, Aron J Huckaba, Sean Parkin, Edith C Glazer

Inorg Chem· July 2023

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A monoadduct generating Ru(ii) complex induces ribosome biogenesis stress and is a molecular mimic of phenanthriplatin.
Richard J Mitchell, Sarah M Kriger, Alexander D Fenton, Dmytro Havrylyuk, Ankit Pandeya, Edith C Glazer

RSC Chem Biol· May 2023

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Synthesis and photobiological evaluation of Ru(II) complexes with expanded chelate polypyridyl ligands.
Raphael T Ryan, Austin C Hachey, Kimberly Stevens, Sean R Parkin, Richard J Mitchell, Edith C Glazer

J Inorg Biochem· January 2023

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Design of Cytochrome P450 1B1 Inhibitors a Scaffold-Hopping Approach.
Austin C Hachey, Alexander D Fenton, David K Heidary, Edith C Glazer

J Med Chem· January 2023

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Ru(II) photocages enable precise control over enzyme activity with red light.
Dmytro Havrylyuk, Austin C Hachey, Alexander Fenton, David K Heidary, Edith C Glazer

Nat Commun· June 2022

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Fine-Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity.
Houston D Cole, John A Roque, Liubov M Lifshits, Rachel Hodges, Patrick C Barrett, Edith C Glazer

Photochem Photobiol· January 2022

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Preface: Memorial Issue Dedicated to Karen J. Brewer.
Joseph S Merola, Edith C Glazer, Sherri A McFarland

Photochem Photobiol· January 2022

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A Fluorometric CYP19A1 (Aromatase) Activity Assay in Live Cells.
David K Heidary, Sarah M Kriger, Austin C Hachey, Edith C Glazer

ChemMedChem· September 2021

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Biological Investigations of Ru(II) Complexes With Diverse β-diketone Ligands.
Raphael T Ryan, Dmytro Havrylyuk, Kimberly C Stevens, L Henry Moore, Sean Parkin, Edith C Glazer

Eur J Inorg Chem· September 2021

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Biological activities of polypyridyl-type ligands: implications for bioinorganic chemistry and light-activated metal complexes.
Austin C Hachey, Dmytro Havrylyuk, Edith C Glazer

Curr Opin Chem Biol· April 2021

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Organoplatinum(II) Complexes Self-Assemble and Recognize AT-Rich Duplex DNA Sequences.
Ana Zamora, Erin Wachter, María Vera, David K Heidary, Venancio Rodríguez, Edith C Glazer

Inorg Chem· February 2021

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Avobenzone incorporation in a diverse range of Ru(II) scaffolds produces potent potential antineoplastic agents.
Raphael T Ryan, Dmytro Havrylyuk, Kimberly C Stevens, L Henry Moore, Doo Young Kim, Edith C Glazer

Dalton Trans· September 2020

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Photochemical and Photobiological Properties of Pyridyl-pyrazol(in)e-Based Ruthenium(II) Complexes with Sub-micromolar Cytotoxicity for Phototherapy.
Dmytro Havrylyuk, David K Heidary, Yang Sun, Sean Parkin, Edith C Glazer

ACS Omega· August 2020

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Bis-tridentate N-Heterocyclic Carbene Ru(II) Complexes are Promising New Agents for Photodynamic Therapy.
Raphael T Ryan, Kimberly C Stevens, Rosemary Calabro, Sean Parkin, Jumanah Mahmoud, Edith C Glazer

Inorg Chem· July 2020

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Strained, Photoejecting Ru(II) Complexes that are Cytotoxic Under Hypoxic Conditions.
John Roque, Dmytro Havrylyuk, Patrick C Barrett, Tariq Sainuddin, Julia McCain, Edith C Glazer

Photochem Photobiol· March 2020

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Toward Optimal Ru(II) Photocages: Balancing Photochemistry, Stability, and Biocompatibility Through Fine Tuning of Steric, Electronic, and Physiochemical Features.
Dmytro Havrylyuk, Kimberly Stevens, Sean Parkin, Edith C Glazer

Inorg Chem· January 2020

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Ru(ii) complexes with diazine ligands: electronic modulation of the coordinating group is key to the design of "dual action" photoactivated agents.
Dmytro Havrylyuk, Megha Deshpande, Sean Parkin, Edith C Glazer

Chem Commun (Camb)· November 2018

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Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450 Variant.
Inacrist Geronimo, Catherine A Denning, David K Heidary, Edith C Glazer, Christina M Payne

Biophys J· October 2018

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Bacterial Cytological Profiling Reveals the Mechanism of Action of Anticancer Metal Complexes.
Yang Sun, David K Heidary, Zhihui Zhang, Christopher I Richards, Edith C Glazer

Mol Pharm· August 2018

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Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines.
Dmytro Havrylyuk, Brock S Howerton, Leona Nease, Sean Parkin, David K Heidary, Edith C Glazer

Eur J Med Chem· August 2018

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