Publications by authors named "Edith Hamel"

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Neurovascular coupling and functional connectivity changes through the Alzheimer's disease spectrum: Effects of simvastatin treatment.
Aline R Zimmer, Miled Bourourou, Frédéric Lesage, Edith Hamel

Alzheimers Dement· August 2025

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Proteome Profiling of Brain Vessels in a Mouse Model of Cerebrovascular Pathology.
Arsalan S Haqqani, Zainab Mianoor, Alexandra T Star, Flavie E Detcheverry, Christie E Delaney, Edith Hamel

Biology (Basel)· December 2023

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Alzheimer's disease and cerebrovascular pathology alter inward rectifier potassium (K 2.1) channels in endothelium of mouse cerebral arteries.
María Lacalle-Aurioles, Lianne J Trigiani, Miled Bourourou, Clotilde Lecrux, Edith Hamel

Br J Pharmacol· May 2022

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Simvastatin rescues memory and granule cell maturation through the Wnt/β-catenin signaling pathway in a mouse model of Alzheimer's disease.
Xin-Kang Tong, Jessika Royea, Edith Hamel

Cell Death Dis· April 2022

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A functional cerebral endothelium is necessary to protect against cognitive decline.
Lianne J Trigiani, Miled Bourourou, María Lacalle-Aurioles, Clotilde Lecrux, Amy Hynes, Edith Hamel

J Cereb Blood Flow Metab· January 2022

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Impaired Hippocampal Neurovascular Coupling in a Mouse Model of Alzheimer's Disease.
Lin Li, Xin-Kang Tong, Mohammadamin Hosseini Kahnouei, Diane Vallerand, Edith Hamel

Front Physiol· August 2021

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A Longitudinal Pilot Study on Cognition and Cerebral Hemodynamics in a Mouse Model of Preeclampsia Superimposed on Hypertension: Looking at Mothers and Their Offspring.
Lianne J Trigiani, Clotilde Lecrux, Jessika Royea, Julie L Lavoie, Frédéric Lesage, Edith Hamel

Front Physiol· February 2021

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New Mechanistic Insights, Novel Treatment Paradigms, and Clinical Progress in Cerebrovascular Diseases.
Johannes Boltze, Jaroslaw A Aronowski, Jerome Badaut, Marion S Buckwalter, Mateo Caleo, Edith Hamel

Front Aging Neurosci· January 2021

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Brain angiotensin II and angiotensin IV receptors as potential Alzheimer's disease therapeutic targets.
Jessika Royea, Edith Hamel

Geroscience· October 2020

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Benefits of physical exercise on cognition and glial white matter pathology in a mouse model of vascular cognitive impairment and dementia.
Lianne J Trigiani, María Lacalle-Aurioles, Miled Bourourou, Lijun Li, Andrew D Greenhalgh, Edith Hamel

Glia· September 2020

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Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-β from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy.
Roxana O Carare, Roxana Aldea, Nivedita Agarwal, Brian J Bacskai, Ingo Bechman, Edith Hamel

Alzheimers Dement (Amst)· August 2020

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AT2R's (Angiotensin II Type 2 Receptor's) Role in Cognitive and Cerebrovascular Deficits in a Mouse Model of Alzheimer Disease.
Jessika Royea, Maria Lacalle-Aurioles, Lianne J Trigiani, Alice Fermigier, Edith Hamel

Hypertension· June 2020

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Memory and cerebrovascular deficits recovered following angiotensin IV intervention in a mouse model of Alzheimer's disease.
Jessika Royea, Pauline Martinot, Edith Hamel

Neurobiol Dis· February 2020

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Proceedings from the Albert Charitable Trust Inaugural Workshop on white matter and cognition in aging.
Farzaneh A Sorond, Shawn Whitehead, Ken Arai, Douglas Arnold, S Thomas Carmichael, Edith Hamel

Geroscience· February 2020

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Comparative benefits of simvastatin and exercise in a mouse model of vascular cognitive impairment and dementia.
Lianne J Trigiani, Jessika Royea, Xin-Kang Tong, Edith Hamel

FASEB J· December 2019

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How reliable is cerebral blood flow to map changes in neuronal activity?
Clotilde Lecrux, Miled Bourourou, Edith Hamel

Auton Neurosci· March 2019

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Spatial memory formation requires netrin-1 expression by neurons in the adult mammalian brain.
Edwin W Wong, Stephen D Glasgow, Lianne J Trigiani, Daryan Chitsaz, Vladimir Rymar, Edith Hamel

Learn Mem· March 2019

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Vascular dysfunction-The disregarded partner of Alzheimer's disease.
Melanie D Sweeney, Axel Montagne, Abhay P Sagare, Daniel A Nation, Lon S Schneider, Edith Hamel

Alzheimers Dement· January 2019

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High cholesterol triggers white matter alterations and cognitive deficits in a mouse model of cerebrovascular disease: benefits of simvastatin.
Xin-Kang Tong, Lianne J Trigiani, Edith Hamel

Cell Death Dis· January 2019

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Pleiotropic Benefits of the Angiotensin Receptor Blocker Candesartan in a Mouse Model of Alzheimer Disease.
Lianne J Trigiani, Jessika Royea, María Lacalle-Aurioles, Xin-Kang Tong, Edith Hamel

Hypertension· November 2018

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Brain Perfusion and Astrocytes.
Bruno Cauli, Edith Hamel

Trends Neurosci· July 2018

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Transforming growth factor-β1 induces cerebrovascular dysfunction and astrogliosis through angiotensin II type 1 receptor-mediated signaling pathways.
Brice Ongali, Nektaria Nicolakakis, Xin-Kang Tong, Clotilde Lecrux, Hans Imboden, Edith Hamel

Can J Physiol Pharmacol· May 2018

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An endothelial link between the benefits of physical exercise in dementia.
Lianne J Trigiani, Edith Hamel

J Cereb Blood Flow Metab· August 2017

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Angiotensin IV Receptors Mediate the Cognitive and Cerebrovascular Benefits of Losartan in a Mouse Model of Alzheimer's Disease.
Jessika Royea, Luqing Zhang, Xin-Kang Tong, Edith Hamel

J Neurosci· May 2017

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Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice.
Prateep Pakavathkumar, Anastasia Noël, Clotilde Lecrux, Agne Tubeleviciute-Aydin, Edith Hamel

Mol Neurodegener· February 2017

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