Publications by authors named "Edward B Leof"

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A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila.
Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof

PLoS Biol· May 2022

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Vardenafil Activity in Lung Fibrosis and In Vitro Synergy with Nintedanib.
Michael H Bourne, Theodore J Kottom, Deanne M Hebrink, Malay Choudhury, Edward B Leof

Cells· December 2021

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SIRT7-mediated modulation of glutaminase 1 regulates TGF-β-induced pulmonary fibrosis.
Malay Choudhury, Xueqian Yin, Kyle J Schaefbauer, Jeong-Han Kang, Bhaskar Roy, Edward B Leof

FASEB J· July 2020

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IPF pathogenesis is dependent upon TGFβ induction of IGF-1.
Danielle M Hernandez, Jeong-Han Kang, Malay Choudhury, Mahefatiana Andrianifahanana, Xueqian Yin, Edward B Leof

FASEB J· April 2020

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B7-1 drives TGF-β stimulated pancreatic carcinoma cell migration and expression of EMT target genes.
Jeong-Han Kang, Mi-Yeon Jung, Edward B Leof

PLoS One· March 2020

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Transforming growth factor beta induces fibroblasts to express and release the immunomodulatory protein PD-L1 into extracellular vesicles.
Jeong-Han Kang, Mi-Yeon Jung, Malay Choudhury, Edward B Leof

FASEB J· February 2020

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Hexokinase 2 couples glycolysis with the profibrotic actions of TGF-β.
Xueqian Yin, Malay Choudhury, Jeong-Han Kang, Kyle J Schaefbauer, Mi-Yeon Jung, Edward B Leof

Sci Signal· December 2019

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Fatty acid synthase is required for profibrotic TGF-β signaling.
Mi-Yeon Jung, Jeong-Han Kang, Danielle M Hernandez, Xueqian Yin, Mahefatiana Andrianifahanana, Edward B Leof

FASEB J· July 2018

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Basolateral delivery of the type I transforming growth factor beta receptor is mediated by a dominant-acting cytoplasmic motif.
Xueqian Yin, Jeong-Han Kang, Mahefatiana Andrianifahanana, Youli Wang, Mi-Yeon Jung, Edward B Leof

Mol Biol Cell· October 2017

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CorMatrix Wrapped Around the Adventitia of the Arteriovenous Fistula Outflow Vein Attenuates Venous Neointimal Hyperplasia.
Binxia Yang, Sreenivasulu Kilari, Akshaar Brahmbhatt, Deborah L McCall, Evelyn Nieves Torres, Edward B Leof

Sci Rep· October 2017

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Cell-penetrating peptides selectively targeting SMAD3 inhibit profibrotic TGF-β signaling.
Jeong-Han Kang, Mi-Yeon Jung, Xueqian Yin, Mahefatiana Andrianifahanana, Danielle M Hernandez, Edward B Leof

J Clin Invest· June 2017

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Profibrotic up-regulation of glucose transporter 1 by TGF-β involves activation of MEK and mammalian target of rapamycin complex 2 pathways.
Mahefatiana Andrianifahanana, Danielle M Hernandez, Xueqian Yin, Jeong-Han Kang, Mi-Yeon Jung, Edward B Leof

FASEB J· November 2016

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Hyperglycemia-Induced Modulation of the Physiognomy and Angiogenic Potential of Fibroblasts Mediated by Matrix Metalloproteinase-2: Implications for Venous Stenosis Formation Associated with Hemodialysis Vascular Access in Diabetic Milieu.
Rajiv Janardhanan, Sreenivasulu Kilari, Edward B Leof, Sanjay Misra

J Vasc Res· August 2016

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Tracking and Therapeutic Value of Human Adipose Tissue-derived Mesenchymal Stem Cell Transplantation in Reducing Venous Neointimal Hyperplasia Associated with Arteriovenous Fistula.
Binxia Yang, Akshaar Brahmbhatt, Evelyn Nieves Torres, Brian Thielen, Deborah L McCall, Edward B Leof

Radiology· May 2016

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The Role of Repeat Administration of Adventitial Delivery of Lentivirus-shRNA-Vegf-A in Arteriovenous Fistula to Prevent Venous Stenosis Formation.
Rajiv Janardhanan, Binxia Yang, Sreenivasulu Kilari, Edward B Leof, Debabrata Mukhopadhyay

J Vasc Interv Radiol· April 2016

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Sorting nexin 9 differentiates ligand-activated Smad3 from Smad2 for nuclear import and transforming growth factor β signaling.
Mark C Wilkes, Claire E Repellin, Jeong-Han Kang, Mahefatiana Andrianifahanana, Xueqian Yin, Edward B Leof

Mol Biol Cell· November 2015

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Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis.
Ying Wang, Ying Cao, Satsuki Yamada, Mahesh Thirunavukkarasu, Veronica Nin, Edward B Leof

Arterioscler Thromb Vasc Biol· June 2015

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Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation.
Flore Nallet-Staub, Xueqian Yin, Cristèle Gilbert, Véronique Marsaud, Saber Ben Mimoun, Edward B Leof

Dev Cell· March 2015

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Adventitial transduction of lentivirus-shRNA-VEGF-A in arteriovenous fistula reduces venous stenosis formation.
Binxia Yang, Rajiv Janardhanan, Pawan Vohra, Eddie L Greene, Santanu Bhattacharya, Edward B Leof

Kidney Int· February 2014

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Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases.
Mahefatiana Andrianifahanana, Mark C Wilkes, Shiv K Gupta, Rod A Rahimi, Claire E Repellin, Edward B Leof

FASEB J· November 2013

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Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model.
Rajiv Janardhanan, Binxia Yang, Pawan Vohra, Bhaskar Roy, Sarah Withers, Edward B Leof

Kidney Int· August 2013

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Retromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome.
Xueqian Yin, Stephen J Murphy, Mark C Wilkes, Yan Ji, Edward B Leof

Mol Biol Cell· July 2013

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Fibrosis, regeneration, and aging: playing chess with evolution.
Vicente E Torres, Edward B Leof

J Am Soc Nephrol· August 2011

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Non-Smad transforming growth factor-β signaling regulated by focal adhesion kinase binding the p85 subunit of phosphatidylinositol 3-kinase.
Min Hong, Mark C Wilkes, Sumedha G Penheiter, Shiv K Gupta, Maryanne Edens, Edward B Leof

J Biol Chem· May 2011

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Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2.
Sumedha G Penheiter, Raman Deep Singh, Claire E Repellin, Mark C Wilkes, Maryanne Edens, Edward B Leof

Mol Biol Cell· November 2010

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