Publications by authors named "Edward Cable"

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Single-Nuclei RNA Sequencing Shows the Engagement of PPAR-Delta Target Genes Primarily in Hepatocytes and Cholangiocytes by the Selective PPAR-Delta Agonist Seladelpar.
Tomoo Yamazaki, Yongqiang Yang, David Schöler, Yoshimi Yukawa-Muto, Tetsuya Kouno, Edward E Cable

PPAR Res· November 2025

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Single and Multiple Doses of Seladelpar Decrease Diurnal Markers of Bile Acid Synthesis in Mice.
Edward E Cable, Jeffrey W Stebbins, Jeff D Johnson, Yun-Jung Choi, Jiangao Song

PPAR Res· March 2025

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Peroxisome proliferator-activated receptor delta and liver diseases.
Tomoo Yamazaki, Edward E Cable, Bernd Schnabl

Hepatol Commun· February 2025

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Partial vasopressin 1a receptor agonism reduces portal hypertension and hyperaldosteronism and induces a powerful diuretic and natriuretic effect in rats with cirrhosis and ascites.
Guillermo Fernández-Varo, Wladimiro Jiménez, Edward Cable, Pere Ginès, Geoff Harris

Biomed Pharmacother· September 2023

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OCE-205 in rats and non-human primates: Pharmacokinetic and pharmacodynamic analysis.
Stan Bukofzer, Geoff Harris, Edward E Cable

Curr Res Pharmacol Drug Discov· August 2023

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OCE-205, a Selective V1a Partial Agonist, Reduces Portal Pressure in Rat Models of Portal Hypertension.
Stan Bukofzer, Geoffrey Harris, Susan Song, Edward E Cable

J Exp Pharmacol· July 2023

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Selective PPARδ agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway.
Tetsuya Kouno, Xiao Liu, Huayi Zhao, Tatiana Kisseleva, Edward E Cable

J Biol Chem· July 2022

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The selective PPAR-delta agonist seladelpar reduces ethanol-induced liver disease by restoring gut barrier function and bile acid homeostasis in mice.
Huikuan Chu, Lu Jiang, Bei Gao, Nagsen Gautam, Jawaher A Alamoudi, Edward E Cable

Transl Res· January 2021

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Trace elements in atmospheric wet precipitation in Detroit metropolitan area: Levels and possible sources.
Edward Cable, Yiwei Deng

Chemosphere· November 2018

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Vasopressin 1a receptor partial agonism increases sodium excretion and reduces portal hypertension and ascites in cirrhotic rats.
Guillermo Fernández-Varo, Denise Oró, Edward Earl Cable, Vedrana Reichenbach, Silvia Carvajal

Hepatology· January 2016

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Native Michigan plants stimulate soil microbial species changes and PAH remediation at a legacy steel mill.
John C Thomas, Edward Cable, Robert T Dabkowski, Stephanie Gargala, Daniel McCall

Int J Phytoremediation· June 2013

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A Potent and Selective AMPK Activator That Inhibits de Novo Lipogenesis.
Jorge E Gómez-Galeno, Qun Dang, Thanh H Nguyen, Serge H Boyer, Matthew P Grote, Edward E Cable

ACS Med Chem Lett· December 2010

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Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist.
Edward E Cable, Patricia D Finn, Jeffrey W Stebbins, Jinzhao Hou, Bruce R Ito

Hepatology· February 2009

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Preclinical pharmacokinetics of a HepDirect prodrug of a novel phosphonate-containing thyroid hormone receptor agonist.
James M Fujitaki, Edward E Cable, Bruce R Ito, Bao-Hong Zhang, Jinzhao Hou

Drug Metab Dispos· November 2008

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Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs.
Serge H Boyer, Hongjian Jiang, Jason D Jacintho, Mali Venkat Reddy, Haiqing Li, Edward E Cable

J Med Chem· November 2008

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Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index.
Mark D Erion, Edward E Cable, Bruce R Ito, Hongjian Jiang, James M Fujitaki

Proc Natl Acad Sci U S A· September 2007

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Expression of E-cadherin and other paracellular junction genes is decreased in iron-loaded hepatocytes.
John P Bilello, Edward E Cable, Harriet C Isom

Am J Pathol· April 2003

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Comparison of anti-hepatitis B virus activities of lamivudine and clevudine by a quantitative assay.
Ayman M Abdelhamed, Colleen M Kelley, Thomas G Miller, Phillip A Furman, Edward E Cable

Antimicrob Agents Chemother· January 2003

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The lipophilic iron compound TMH-ferrocene [(3,5,5-trimethylhexanoyl)ferrocene] increases iron concentrations, neuronal L-ferritin, and heme oxygenase in brains of BALB/c mice.
Elise A Malecki, Edward E Cable, Harriet C Isom, James R Connor

Biol Trace Elem Res· April 2002

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Effects of modulators of protein phosphorylation on heme metabolism in human hepatic cells: induction of delta-aminolevulinic synthase mRNA and protein by okadaic acid.
Edward E Cable, Benjamin R Kuhn, Harriet C Isom

DNA Cell Biol· April 2002

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