Publications by authors named "Edward Doherty"

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Dysregulated alveolar type 2 epithelial cell proteostasis promotes fibrogenic macrophage migration inhibitory factor-CD74 signaling.
Sang-Hun Kim, Jessica Nouws, Jannik Ruwisch, Gavitt A Woodard, Joseph Cooley, Edward Doherty

Sci Transl Med· December 2025

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First-in-Human Clinical Trial of Vaccination with WDVAX, a Dendritic Cell-Activating Scaffold Incorporating Autologous Tumor Cell Lysate, in Patients with Metastatic Melanoma.
F Stephen Hodi, Anita Giobbie-Hurder, Kwasi Adu-Berchie, Srin Ranasinghe, Ana Lako, Edward J Doherty

Cancer Immunol Res· July 2025

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CD74 promotes the formation of an immunosuppressive tumor microenvironment in triple-negative breast cancer in mice by inducing the expansion of tolerogenic dendritic cells and regulatory B cells.
Bianca Pellegrino, Keren David, Stav Rabani, Bar Lampert, Thuy Tran, Edward Doherty

PLoS Biol· November 2024

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Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock.
Michael Super, Edward J Doherty, Mark J Cartwright, Benjamin T Seiler, Fernanda Langellotto

Nat Biomed Eng· January 2022

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A Modular Biomaterial Scaffold-Based Vaccine Elicits Durable Adaptive Immunity to Subunit SARS-CoV-2 Antigens.
Fernanda Langellotto, Maxence O Dellacherie, Chyenne Yeager, Hamza Ijaz, Jingyou Yu, Edward J Doherty

Adv Healthc Mater· November 2021

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Sclerostin antibody stimulates periodontal regeneration in large alveolar bone defects.
Yao Yao, Frederic Kauffmann, Shogo Maekawa, Lea V Sarment, James V Sugai, Edward J Doherty

Sci Rep· October 2020

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Combined delivery of VEGF and IGF-1 promotes functional innervation in mice and improves muscle transplantation in rabbits.
Theresa M Raimondo, Hehuan Li, Brian J Kwee, Sarah Kinsley, Erica Budina, Edward J Doherty

Biomaterials· September 2019

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Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus.
Joshua B Bilsborrow, Edward Doherty, Pathricia V Tilstam, Richard Bucala

Expert Opin Ther Targets· September 2019

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VEGF and IGF Delivered from Alginate Hydrogels Promote Stable Perfusion Recovery in Ischemic Hind Limbs of Aged Mice and Young Rabbits.
Erin M Anderson, Eduardo A Silva, Yibai Hao, Kathleen D Martinick, Sarah A Vermillion, Elisabeth G Doherty, Edward J Doherty

J Vasc Res· October 2017

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Measurement of Mitochondrial Mass by Flow Cytometry during Oxidative Stress.
Edward Doherty, Andras Perl

React Oxyg Species (Apex)· July 2017

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Increased mitochondrial electron transport chain activity at complex I is regulated by N-acetylcysteine in lymphocytes of patients with systemic lupus erythematosus.
Edward Doherty, Zachary Oaks, Andras Perl

Antioxid Redox Signal· July 2014

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Relationship of vaccine efficacy to the kinetics of DC and T-cell responses induced by PLG-based cancer vaccines.
Omar A Ali, Edward Doherty, David J Mooney, Dwaine Emerich

Biomatter· March 2014

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Identification of immune factors regulating antitumor immunity using polymeric vaccines with multiple adjuvants.
Omar A Ali, Catia Verbeke, Chris Johnson, R Warren Sands, Sarah A Lewin, Edward Doherty

Cancer Res· March 2014

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Assessment of mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus.
Andras Perl, Robert Hanczko, Edward Doherty

Methods Mol Biol· January 2013

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N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial.
Zhi-Wei Lai, Robert Hanczko, Eduardo Bonilla, Tiffany N Caza, Brandon Clair, Edward Doherty

Arthritis Rheum· September 2012

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The efficacy of intracranial PLG-based vaccines is dependent on direct implantation into brain tissue.
Omar A Ali, Edward Doherty, William J Bell, Tracie Fradet, Jebecka Hudak

J Control Release· September 2011

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Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance.
Max A Tischfield, Hagit N Baris, Chen Wu, Guenther Rudolph, Lionel Van Maldergem, Edward J Doherty

Cell· January 2010

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T-cell and B-cell signaling biomarkers and treatment targets in lupus.
Andras Perl, David R Fernandez, Tiffany Telarico, Edward Doherty, Lisa Francis

Curr Opin Rheumatol· September 2009

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Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine.
Robert Hanczko, David R Fernandez, Edward Doherty, Yueming Qian, Gyorgy Vas

J Clin Invest· June 2009

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Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE.
Andras Perl, Gyorgy Nagy, Agnes Koncz, Peter Gergely, David Fernandez, Edward Doherty

Autoimmunity· May 2008

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