Publications by authors named "Edward Fitzgerald"

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Detection and characterisation of ligand-induced conformational changes in acetylcholine binding proteins using biosensors and X-ray crystallography.
Edward A FitzGerald, Daniela Cederfelt, Daria Kovryzhenko, Pierre Boronat, Bjarte Aarmo Lund

RSC Chem Biol· October 2025

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Binding-Site Purification of Actives (B-SPA) Enables Efficient Large-Scale Progression of Fragment Hits by Combining Multi-Step Array Synthesis With HT Crystallography.
Harold Grosjean, Anthony Aimon, Storm Hassell-Hart, Warren Thompson, Lizbé Koekemoer, Edward A FitzGerald

Angew Chem Int Ed Engl· April 2025

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Integrated computational and biosensor-based strategies for the discovery of allosteric SMYD3 ligands using diperodon as a starting point.
Edward A FitzGerald, Moira M Rachman, Daniela Cederfelt, Nadine E M Myers, Daria Kovryzchenko

Bioorg Med Chem· April 2025

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Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening.
Edward A FitzGerald, Daniela Cederfelt, Bjarte Aarmo Lund, Nadine E M Myers, He Zhang

RSC Med Chem· June 2024

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Accelerating BRPF1b hit identification with BioPhysical and Active Learning Screening (BioPALS).
Sandeep Pal, Zandile Nare, Vincenzo A Rao, Brian O Smith, Ian Morrison, Edward A Fitzgerald

ChemMedChem· March 2024

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Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors.
Edward A FitzGerald, Darius Vagrys, Giulia Opassi, Hanna F Klein, David J Hamilton

SLAS Discov· January 2024

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Digital health technology-specific risks for medical malpractice liability.
Simon P Rowland, J Edward Fitzgerald, Matthew Lungren, Elizabeth Hsieh Lee, Zach Harned

NPJ Digit Med· October 2022

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Discovery of an Allosteric Ligand Binding Site in SMYD3 Lysine Methyltransferase.
Vladimir O Talibov, Edoardo Fabini, Edward A FitzGerald, Daniele Tedesco, Daniela Cederfeldt

Chembiochem· May 2021

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Discovery of fragments inducing conformational effects in dynamic proteins using a second-harmonic generation biosensor.
Edward A FitzGerald, Margaret T Butko, Pierre Boronat, Daniela Cederfelt, Mia Abramsson

RSC Adv· February 2021

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Real-world use of workplace based assessments in surgical training: A UK nationwide cross-sectional exploration of trainee perspectives and consensus recommendations from the Association of Surgeons in Training.
Andrew J Beamish, Maximilian J Johnston, Rhiannon L Harries, Helen M Mohan, J Edward F Fitzgerald

Int J Surg· December 2020

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Proteomic and Metabolomic Characterization of Human Neurovascular Unit Cells in Response to Methamphetamine.
Anna Herland, Ben M Maoz, Edward A FitzGerald, Thomas Grevesse, Charles Vidoudez

Adv Biosyst· September 2020

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Robotic fluidic coupling and interrogation of multiple vascularized organ chips.
Richard Novak, Miles Ingram, Susan Marquez, Debarun Das, Aaron Delahanty, Edward A FitzGerald

Nat Biomed Eng· April 2020

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Impact of geo-imputation on epidemiologic associations in a study of outdoor air pollution and respiratory hospitalization.
Rena R Jones, Francis P Boscoe, Danielle N Medgyesi, Edward F Fitzgerald, Syni-An Hwang

Spat Spatiotemporal Epidemiol· February 2020

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A longitudinal study of polychlorinated biphenyls and neuropsychological function among older adults from New York State.
Eva M Tanner, Michael S Bloom, Kurunthachalam Kannan, Julie Lynch, Wei Wang, Edward F Fitzgerald

Int J Hyg Environ Health· January 2020

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What is the clinical value of mHealth for patients?
Simon P Rowland, J Edward Fitzgerald, Thomas Holme, John Powell, Alison McGregor

NPJ Digit Med· January 2020

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Surgical trainees' experience of pregnancy, maternity and paternity leave: a cross-sectional study.
Helen Mohan, Oroog Ali, Vimal Gokani, Ciara McGoldrick, Peter Smitham, J Edward F Fitzgerald

Postgrad Med J· October 2019

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Medical equipment donation in low-resource settings: a review of the literature and guidelines for surgery and anaesthesia in low-income and middle-income countries.
Isobel H Marks, Hannah Thomas, Marize Bakhet, Edward Fitzgerald

BMJ Glob Health· September 2019

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Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.
Tae-Eun Park, Nur Mustafaoglu, Anna Herland, Ryan Hasselkus, Robert Mannix, Edward A FitzGerald

Nat Commun· June 2019

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A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells.
Ben M Maoz, Anna Herland, Edward A FitzGerald, Thomas Grevesse, Charles Vidoudez

Nat Biotechnol· October 2018

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Maternal ambient heat exposure during early pregnancy in summer and spring and congenital heart defects - A large US population-based, case-control study.
Shao Lin, Ziqiang Lin, Yanqiu Ou, Aida Soim, Srishti Shrestha, Edward Fitzgerald

Environ Int· September 2018

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Pressure of academic publishing for medical students: a student's perspective.
Jeevahan Mahalingam, Chetan Khatri, J Edward Fitzgerald

Postgrad Med J· June 2018

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Engagement and role of surgical trainees in global surgery: Consensus statement and recommendations from the Association of Surgeons in Training.
Helen M Mohan, Edward Fitzgerald, Vimal Gokani, Paul Sutton, Rhiannon Harries

Int J Surg· April 2018

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Surgical safety checklist training: a national study of undergraduate medical and nursing student teaching, understanding and influencing factors.
Caroline Laura Stephanie Kilduff, Thomas Oliver Leith, Thomas M Drake, J Edward F Fitzgerald

Postgrad Med J· March 2018

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Impact of Surgical Lighting on Intraoperative Safety in Low-Resource Settings: A Cross-Sectional Survey of Surgical Providers.
Jared A Forrester, Nicholas J Boyd, J Edward F Fitzgerald, Iain H Wilson, Abebe Bekele

World J Surg· December 2017

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Cross-sectional study of the financial cost of training to the surgical trainee in the UK and Ireland.
John O'Callaghan, Helen M Mohan, Anna Sharrock, Vimal Gokani, J Edward Fitzgerald

BMJ Open· November 2017

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