Publications by authors named "Edward G D Tuddenham"

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Sustained Clinical Benefit of AAV Gene Therapy in Severe Hemophilia B.
Ulrike M Reiss, Andrew M Davidoff, Edward G D Tuddenham, Pratima Chowdary, Jenny McIntosh

N Engl J Med· June 2025

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Mathematical models of coagulation-are we there yet?
Matt J Owen, Joy R Wright, Edward G D Tuddenham, John R King, Alison H Goodall

J Thromb Haemost· June 2024

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The complex, confusing and poorly understood immune responses to AAV-mediated gene transfer in haemophilia-Is more or less immunosuppression required?
Edward G D Tuddenham, Graham R Foster

J Viral Hepat· April 2024

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Haemophilia, the journey in search of a cure. 1960-2020.
Amit C Nathwani, Edward G D Tuddenham

Br J Haematol· November 2020

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Factor VIII: the protein, cloning its gene, synthetic factor and now - 35 years later - gene therapy; what happened in between?
Gavin Ling, Edward G D Tuddenham

Br J Haematol· May 2020

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Interaction Between the a3 Region of Factor VIII and the TIL'E' Domains of the von Willebrand Factor.
Lisbeth Dagil, Kathrin S Troelsen, Gert Bolt, Lars Thim, Bo Wu, Edward G D Tuddenham

Biophys J· August 2019

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Recent advances in developing specific therapies for haemophilia.
Gavin Ling, Amit C Nathwani, Edward G D Tuddenham

Br J Haematol· April 2018

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Advances in Gene Therapy for Hemophilia.
Amit C Nathwani, Andrew M Davidoff, Edward G D Tuddenham

Hum Gene Ther· November 2017

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Gene Therapy for Hemophilia.
Amit C Nathwani, Andrew M Davidoff, Edward G D Tuddenham

Hematol Oncol Clin North Am· October 2017

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Long-term safety and efficacy of factor IX gene therapy in hemophilia B.
Amit C Nathwani, Ulreke M Reiss, Edward G D Tuddenham, Cecilia Rosales, Pratima Chowdary

N Engl J Med· November 2014

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Solution structure of the major factor VIII binding region on von Willebrand factor.
Nuha Shiltagh, John Kirkpatrick, Lisa D Cabrita, Tom A J McKinnon, Konstantinos Thalassinos, Edward G D Tuddenham

Blood· June 2014

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Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.
Jenny McIntosh, Peter J Lenting, Cecilia Rosales, Doyoung Lee, Samira Rabbanian, Edward G D Tuddenham

Blood· April 2013

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AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage.
Christopher Binny, Jenny McIntosh, Marco Della Peruta, Hanna Kymalainen, Edward G D Tuddenham

Blood· January 2012

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Adenovirus-associated virus vector-mediated gene transfer in hemophilia B.
Amit C Nathwani, Edward G D Tuddenham, Savita Rangarajan, Cecilia Rosales, Jenny McIntosh

N Engl J Med· December 2011

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Human congenital diseases with mixed modes of inheritance have a shortage of recessive disease. A demographic scenario?
N Avrion Mitchison, Shomi Bhattacharya, Edward G D Tuddenham

Ann Hum Genet· November 2011

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Codon optimization of human factor VIII cDNAs leads to high-level expression.
Natalie J Ward, Suzanne M K Buckley, Simon N Waddington, Thierry Vandendriessche, Marinee K L Chuah, Edward G D Tuddenham

Blood· January 2011

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Menorrhagia in adolescents with inherited bleeding disorders.
Claudia Chi, Debra Pollard, Edward G D Tuddenham, Rezan A Kadir

J Pediatr Adolesc Gynecol· August 2010

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Alpha1-antitrypsin Pittsburgh in a family with bleeding tendency.
Baolai Hua, Liankai Fan, Yan Liang, Yongqiang Zhao, Edward G D Tuddenham

Haematologica· June 2009

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Killing 2 birds with 1 stone.
Edward G D Tuddenham

Blood· October 2008

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Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation.
Daniel P Gale, Sarah K Harten, Cecil D L Reid, Edward G D Tuddenham, Patrick H Maxwell

Blood· August 2008

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Genotype-phenotype correlation in combined deficiency of factor V and factor VIII.
Bin Zhang, Marta Spreafico, Chunlei Zheng, Angela Yang, Petra Platzer, Edward G D Tuddenham

Blood· June 2008

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Identification of factor IX mutations in Iranian haemophilia B patients by SSCP and sequencing.
Morteza Karimipoor, Sirous Zeinali, Nafiseh Nafissi, Edward G D Tuddenham, Manijeh Lak

Thromb Res· June 2007

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Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates.
Amit C Nathwani, John T Gray, Jenny McIntosh, Catherine Y C Ng, Junfang Zhou, Edward G D Tuddenham

Blood· February 2007

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Live birth following the first mutation specific pre-implantation genetic diagnosis for haemophilia A.
Katerina Michaelides, Edward G D Tuddenham, Cathy Turner, Ben Lavender, Stuart A Lavery

Thromb Haemost· February 2006

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Ways to bypass a blocked tenase complex.
Edward G D Tuddenham

Thromb Haemost· January 2006

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