Publications by authors named "Edward Leithe"

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The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation.
Max Zachrisson Totland, Lars Mørland Knudsen, Nikoline Lander Rasmussen, Yasufumi Omori, Vigdis Sørensen, Edward Leithe

Cell Mol Life Sci· April 2024

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Endocytic trafficking of connexins in cancer pathogenesis.
Max Zachrisson Totland, Yasufumi Omori, Vigdis Sørensen, Kushtrim Kryeziu, Trond Aasen, Edward Leithe

Biochim Biophys Acta Mol Basis Dis· October 2023

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Regulation of gap junction intercellular communication by connexin ubiquitination: physiological and pathophysiological implications.
Max Zachrisson Totland, Nikoline Lander Rasmussen, Lars Mørland Knudsen, Edward Leithe

Cell Mol Life Sci· February 2020

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Connexins in cancer: bridging the gap to the clinic.
Trond Aasen, Edward Leithe, Sheila V Graham, Petra Kameritsch, María D Mayán

Oncogene· June 2019

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The connexin 43 C-terminus: A tail of many tales.
Edward Leithe, Marc Mesnil, Trond Aasen

Biochim Biophys Acta Biomembr· January 2018

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An update on minding the gap in cancer.
Marc Mesnil, Trond Aasen, Jonathan Boucher, Amandine Chépied, Laurent Cronier, Edward Leithe

Biochim Biophys Acta Biomembr· January 2018

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The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions.
Max Z Totland, Christian H Bergsland, Tone A Fykerud, Lars M Knudsen, Nikoline L Rasmussen, Edward Leithe

J Cell Sci· September 2017

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Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1.
Anita Sveen, Bjarne Johannessen, Torstein Tengs, Stine A Danielsen, Ina A Eilertsen, Edward Leithe

Genome Med· May 2017

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A protein kinase A-ezrin complex regulates connexin 43 gap junction communication in liver epithelial cells.
Aleksandra R Dukic, Linda Hofstad Haugen, Guillaume Pidoux, Edward Leithe, Oddmund Bakke

Cell Signal· April 2017

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Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding.
Tone A Fykerud, Lars M Knudsen, Max Z Totland, Vigdis Sørensen, Shiva Dahal-Koirala, Edward Leithe

Cell Cycle· November 2016

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Regulation of connexins by the ubiquitin system: Implications for intercellular communication and cancer.
Edward Leithe

Biochim Biophys Acta· April 2016

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Regulator of Chromosome Condensation 2 Identifies High-Risk Patients within Both Major Phenotypes of Colorectal Cancer.
Jarle Bruun, Matthias Kolberg, Terje C Ahlquist, Ellen C Røyrvik, Torfinn Nome, Edward Leithe

Clin Cancer Res· August 2015

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Connexins in colorectal cancer pathogenesis.
Solveig Sirnes, Guro E Lind, Jarle Bruun, Tone A Fykerud, Marc Mesnil, Edward Leithe

Int J Cancer· July 2015

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Portrait of the PI3K/AKT pathway in colorectal cancer.
Stine Aske Danielsen, Peter Wold Eide, Arild Nesbakken, Tormod Guren, Edward Leithe

Biochim Biophys Acta· January 2015

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NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.
Peter W Eide, Lina Cekaite, Stine A Danielsen, Ina A Eilertsen, Ane Kjenseth, Edward Leithe

Cell Signal· January 2013

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Smad ubiquitination regulatory factor-2 controls gap junction intercellular communication by modulating endocytosis and degradation of connexin43.
Tone Aase Fykerud, Ane Kjenseth, Kay Oliver Schink, Solveig Sirnes, Jarle Bruun, Edward Leithe

J Cell Sci· September 2012

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Connexin43 acts as a colorectal cancer tumor suppressor and predicts disease outcome.
Solveig Sirnes, Jarle Bruun, Matthias Kolberg, Ane Kjenseth, Guro E Lind, Edward Leithe

Int J Cancer· August 2012

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Endocytosis and post-endocytic sorting of connexins.
Edward Leithe, Solveig Sirnes, Tone Fykerud, Ane Kjenseth, Edgar Rivedal

Biochim Biophys Acta· August 2012

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The gap junction channel protein connexin 43 is covalently modified and regulated by SUMOylation.
Ane Kjenseth, Tone A Fykerud, Solveig Sirnes, Jarle Bruun, Zeremariam Yohannes, Edward Leithe

J Biol Chem· May 2012

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Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting.
Lene Malerød, Nina Marie Pedersen, Catherine Elisabeth Sem Wegner, Viola Hélène Lobert, Edward Leithe

Traffic· September 2011

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Norepinephrine inhibits intercellular coupling in rat cardiomyocytes by ubiquitination of connexin43 gap junctions.
Sarah Mollerup, Johannes P Hofgaard, Thomas H Braunstein, Ane Kjenseth, Edward Leithe

Cell Commun Adhes· August 2011

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DNA methylation analyses of the connexin gene family reveal silencing of GJC1 (Connexin45) by promoter hypermethylation in colorectal cancer.
Solveig Sirnes, Hilde Honne, Deeqa Ahmed, Stine Aske Danielsen, Torleiv O Rognum, Edward Leithe

Epigenetics· May 2011

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Regulation of gap junction intercellular communication by the ubiquitin system.
Ane Kjenseth, Tone Fykerud, Edgar Rivedal, Edward Leithe

Cell Signal· September 2010

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Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil.
Edward Leithe, Ane Kjenseth, Jarle Bruun, Solveig Sirnes, Edgar Rivedal

Toxicol Appl Pharmacol· August 2010

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Gap junction intercellular communication and benzene toxicity.
Edgar Rivedal, Gisela Witz, Edward Leithe

Chem Biol Interact· March 2010

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