Publications by authors named "Edward Macarak"

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Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis.
Morgan D Basta, Svetlana Petruk, Ross Summer, Joel Rosenbloom, Peter J Wermuth, Edward Macarak

iScience· May 2023

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Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases.
Edward J Macarak, Peter J Wermuth, Joel Rosenbloom, Jouni Uitto

Exp Dermatol· January 2021

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Therapeutic Approaches to Radiation-Induced Fibrosis.
Edward J Macarak, Joel Rosenbloom

J Cancer Treatment Diagn· August 2018

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Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion formation.
Edward J Macarak, Christine E Lotto, Deepika Koganti, Xiaoling Jin, Peter J Wermuth

J Surg Res· July 2018

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Human Fibrotic Diseases: Current Challenges in Fibrosis Research.
Joel Rosenbloom, Edward Macarak, Sonsoles Piera-Velazquez, Sergio A Jimenez

Methods Mol Biol· May 2018

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New frontiers in fibrotic disease therapies: The focus of the Joan and Joel Rosenbloom Center for Fibrotic Diseases at Thomas Jefferson University.
Joel Rosenbloom, Shumei Ren, Edward Macarak

Matrix Biol· April 2016

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Pathobiological mechanisms of peritoneal adhesions: The mesenchymal transition of rat peritoneal mesothelial cells induced by TGF-β1 and IL-6 requires activation of Erk1/2 and Smad2 linker region phosphorylation.
Xiaoling Jin, Shumei Ren, Edward Macarak, Joel Rosenbloom

Matrix Biol· April 2016

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Keloids: The paradigm of skin fibrosis - Pathomechanisms and treatment.
Jonathan P Andrews, Jaana Marttala, Edward Macarak, Joel Rosenbloom, Jouni Uitto

Matrix Biol· April 2016

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Keloid Pathogenesis: Potential Role of Cellular Fibronectin with the EDA Domain.
Jonathan P Andrews, Jaana Marttala, Edward Macarak, Joel Rosenbloom, Jouni Uitto

J Invest Dermatol· July 2015

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Mechanosensitive release of adenosine 5'-triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: a mechanism for purinergic involvement in chronic strain.
Jonathan M Beckel, Arthur J Argall, Jason C Lim, Jingsheng Xia, Wennan Lu, Edward J Macarak

Glia· September 2014

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Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle.
Catherine Moorwood, Anastassios Philippou, Janelle Spinazzola, Benjamin Keyser, Edward J Macarak

Skelet Muscle· July 2014

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Recombinant insulin-like growth factor-1 activates satellite cells in the mouse urethral rhabdosphincter.
Wenjie Wei, Pamela S Howard, Edward J Macarak

BMC Urol· November 2013

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Urinary diversion results in marked decreases in proliferation and apoptosis in fetal bladder.
Wenjie Wei, Pamela S Howard, Barry Kogan, Edward J Macarak

J Urol· October 2012

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Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors.
Jingsheng Xia, Jason C Lim, Wennan Lu, Jonathan M Beckel, Edward J Macarak

J Physiol· May 2012

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Beta and gamma-sarcoglycans are decreased in the detrusor smooth muscle cells of the partially obstructed rabbit bladder.
Wenjie Wei, Pamela S Howard, Steven A Zderic, Edward J Macarak

J Urol· May 2008

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Altered extracellular matrix expression in the diverted fetal sheep bladder.
Wenjie Wei, Pamela S Howard, Barry Kogan, Edward J Macarak

J Urol· September 2007

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Smooth muscle trans-membrane sarcoglycan complex in partial bladder outlet obstruction.
Edward J Macarak, Jake Schulz, Stephen A Zderic, Yoshikazu Sado, Yoshifumi Ninomiya

Histochem Cell Biol· July 2006

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Compression and tension: differential effects on matrix accumulation by periodontal ligament fibroblasts in vitro.
Yuling He, Edward J Macarak, Jonathan M Korostoff, Pamela S Howard

Connect Tissue Res· November 2004

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Matrix synthesis by bladder smooth muscle cells is modulated by stretch frequency.
Douglas E Coplen, Edward J Macarak, Pamela S Howard

In Vitro Cell Dev Biol Anim· September 2004

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Molecular response of the bladder to obstruction.
Andrew J Kirsch, Edward J Macarak, Brahim Chaqour, Theresa Quinn, Stephen Zderic

Adv Exp Med Biol· May 2004

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Partial bladder outlet obstruction alters Ca2+ sensitivity of force, but not of MLC phosphorylation, in bladder smooth muscle.
Michaela C Stanton, Michele Clement, Edward J Macarak, Stephen A Zderic, Robert S Moreland

Am J Physiol Renal Physiol· October 2003

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Regulation of Cyr61/CCN1 gene expression through RhoA GTPase and p38MAPK signaling pathways.
Ji-Soo Han, Edward Macarak, Joel Rosenbloom, Kwang Chul Chung, Brahim Chaqour

Eur J Biochem· August 2003

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Correlation of P-cadherin and beta-catenin expression and phosphorylation with carcinogenesis in rat tongue cancer induced with 4-nitroquinoline 1-oxide.
Isao Tamura, Toshio Sakaki, Brahim Chaqour, Pamela S Howard, Takashi Ikeo, Edward J Macarak

Oral Oncol· July 2003

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Response of the fetal sheep bladder to urinary diversion.
Seiji Matsumoto, Barry A Kogan, Robert M Levin, Pamela S Howard, Edward J Macarak

J Urol· February 2003

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Cyr61 and CTGF are molecular markers of bladder wall remodeling after outlet obstruction.
Brahim Chaqour, Catherine Whitbeck, Ji-Soo Han, Edward Macarak, Pat Horan

Am J Physiol Endocrinol Metab· October 2002

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