Publications by authors named "Edward Manser"

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Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions.
Paul Atherton, Rafaella Konstantinou, Suat Peng Neo, Emily Wang, Eleonora Balloi, Edward Manser

J Cell Biol· October 2022

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Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis.
Caner Akıl, Linh T Tran, Magali Orhant-Prioux, Yohendran Baskaran, Yosuke Senju, Edward Manser

Commun Biol· August 2022

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Proximity proteomics identifies PAK4 as a component of Afadin-Nectin junctions.
Yohendran Baskaran, Felicia Pei-Ling Tay, Elsa Yuen Wai Ng, Claire Lee Foon Swa, Sheena Wee, Edward Manser

Nat Commun· September 2021

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The structure of the actin filament uncapping complex mediated by twinfilin.
Dennis M Mwangangi, Edward Manser, Robert C Robinson

Sci Adv· January 2021

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Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea.
Caner Akıl, Linh T Tran, Magali Orhant-Prioux, Yohendran Baskaran, Edward Manser

Proc Natl Acad Sci U S A· August 2020

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Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.
Maria I Acosta, Serge Urbach, Anne Doye, Yuen-Wai Ng, Jérôme Boudeau, Edward Manser

Sci Rep· January 2018

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Rho GTPases and regulation of cell migration and polarization in human corneal epithelial cells.
Aihua Hou, Li Xian Toh, Kah Hui Gan, Khee Jin Ryan Lee, Edward Manser

PLoS One· June 2014

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PTB domain-directed substrate targeting in a tyrosine kinase from the unicellular choanoflagellate Monosiga brevicollis.
Victoria Prieto-Echagüe, Perry M Chan, Barbara P Craddock, Edward Manser, W Todd Miller

PLoS One· April 2011

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The leading edge during dorsal closure as a model for epithelial plasticity: Pak is required for recruitment of the Scribble complex and septate junction formation.
Sami Bahri, Simon Wang, Ryan Conder, Juliana Choy, Stephanie Vlachos, Edward Manser

Development· June 2010

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The Drosophila homologue of Arf-GAP GIT1, dGIT, is required for proper muscle morphogenesis and guidance during embryogenesis.
Sami M Bahri, Juliana M Choy, Edward Manser, Louis Lim, Xiaohang Yang

Dev Biol· January 2009

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PAK is regulated by PI3K, PIX, CDC42, and PP2Calpha and mediates focal adhesion turnover in the hyperosmotic stress-induced p38 pathway.
Perry M Chan, Louis Lim, Edward Manser

J Biol Chem· September 2008

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Bcl-xL and UVRAG cause a monomer-dimer switch in Beclin1.
Christian G Noble, Jing-Ming Dong, Edward Manser, Haiwei Song

J Biol Chem· September 2008

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Functional interactions between phosphatase POPX2 and mDia modulate RhoA pathways.
Yi Xie, E-Jean Tan, Shimei Wee, Edward Manser, Louis Lim

J Cell Sci· February 2008

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Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.
Monika Weisz Hubsman, Natalia Volinsky, Edward Manser, Deborah Yablonski, Ami Aronheim

Biochem J· June 2007

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PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition.
Haihe Wang, Samantha Yiling Quah, Jing Ming Dong, Edward Manser, Jing Ping Tang

Cancer Res· April 2007

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PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.
Serge M Gisler, Sandra Pribanic, Desa Bacic, Patrik Forrer, Andrea Gantenbein, Edward Manser

Kidney Int· November 2003

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The GTPase cycle. How dominant inhibitory mutants block the biological functions of small GTPases.
Edward J Manser

Methods Mol Biol· July 2003

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PRL-3 and PRL-1 promote cell migration, invasion, and metastasis.
Qi Zeng, Jing-Ming Dong, Ke Guo, Jie Li, Hui-Xian Tan, Edward Manser

Cancer Res· June 2003

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Cdc42 antagonizes inductive action of cAMP on cell shape, via effects of the myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) on myosin light chain phosphorylation.
Jing-Ming Dong, Thomas Leung, Edward Manser, Louis Lim

Eur J Cell Biol· April 2002

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The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family.
Cheng-Gee Koh, E-Jean Tan, Edward Manser, Louis Lim

Curr Biol· February 2002

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Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK).
Hidemasa Goto, Kazushi Tanabe, Edward Manser, Louis Lim, Yoshihiro Yasui

Genes Cells· February 2002

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