Publications by authors named "Edward Needham"

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Serum neurofilament light chain levels suggest neuroprotection following bexarotene-induced remyelination in people with relapsing remitting multiple sclerosis.
Gioia Riboni-Verri, Chris McMurran, Jens Kuhle, Lisa Hofer, Alasdair Coles, Edward Needham

Mult Scler Relat Disord· November 2025

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Inflammatory Mediators Related to Vascular Dysfunction are Linked to ICP, PRx, and CPP Following Human Severe Traumatic Brain Injury.
Claudia Ann Smith, Caroline Lindblad, Edward Needham, Erta Beqiri, Sofia Bergström

J Neurotrauma· November 2025

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A Technical Assessment of a Commercial GFAP Lateral Flow Assay to Establish Proof-of-Concept for Use in Traumatic Brain Injury.
Daniel P Whitehouse, Edward J Needham, Joshua D Bernstock, Edoardo Gaude, Liam Barrett

Cell Mol Neurobiol· July 2025

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Seronegative autoimmune encephalitis associated with ovarian teratoma and uterine STUMP tumour.
Christopher Niblock, Abigail Richards, Damodar Makkuni, Edward James Needham

BMJ Case Rep· February 2025

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Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction.
Greta K Wood, Brendan F Sargent, Zain-Ul-Abideen Ahmad, Kukatharmini Tharmaratnam, Cordelia Dunai, Edward Needham

Nat Med· January 2025

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Parsimonious immune-response endotypes and global outcome in patients with traumatic brain injury.
Romit J Samanta, Anne-Cécile Chiollaz, Edward Needham, John K Yue, Adel Helmy

EBioMedicine· October 2024

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Changes in memory and cognition during the SARS-CoV-2 human challenge study.
William Trender, Peter J Hellyer, Ben Killingley, Mariya Kalinova, Alex J Mann, Edward Needham

EClinicalMedicine· October 2024

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Pulmonary SARS-CoV-2 infection leads to para-infectious immune activation in the brain.
Cordelia Dunai, Claire Hetherington, Sarah A Boardman, Jordan J Clark, Parul Sharma, Edward J Needham

Front Immunol· October 2024

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FlowAtlas: an interactive tool for high-dimensional immunophenotyping analysis bridging FlowJo with computational tools in Julia.
Valerie Coppard, Grisha Szep, Zoya Georgieva, Sarah K Howlett, Lorna B Jarvis, Edward J Needham

Front Immunol· August 2024

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The potential of gene delivery for the treatment of traumatic brain injury.
James Dooley, Jasmine G Hughes, Edward J Needham, Katerina A Palios, Adrian Liston

J Neuroinflammation· July 2024

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Hepatic encephalopathy: a neurologist's perspective.
Edward Needham, Gwilym Webb

Pract Neurol· May 2024

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Author Correction: Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Benedict D Michael, Cordelia Dunai, Edward J Needham, Kukatharmini Tharmaratnam, Robyn Williams

Nat Commun· April 2024

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Candidate Genetic and Molecular Drivers of Dysregulated Adaptive Immune Responses After Traumatic Brain Injury.
Michał Duchniewicz, John Y W Lee, David K Menon, Edward J Needham

J Neurotrauma· January 2024

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Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses.
Benedict D Michael, Cordelia Dunai, Edward J Needham, Kukatharmini Tharmaratnam, Robyn Williams

Nat Commun· December 2023

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Diagnosis of delirium: a practical approach.
Sian K Alexander, Edward Needham

Pract Neurol· June 2023

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Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.
Edward J Needham, Alexander L Ren, Richard J Digby, Emma J Norton, Soraya Ebrahimi

Brain· November 2022

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Remyelination varies between and within lesions in multiple sclerosis following bexarotene.
J William L Brown, Ferran Prados, Daniel R Altmann, Baris Kanber, Jonathan Stutters, Edward J Needham

Ann Clin Transl Neurol· October 2022

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Neuro-Inflammation Modulation and Post-Traumatic Brain Injury Lesions: From Bench to Bed-Side.
Alice Jacquens, Edward J Needham, Elisa R Zanier, Vincent Degos, Pierre Gressens

Int J Mol Sci· September 2022

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Post-acute blood biomarkers and disease progression in traumatic brain injury.
Virginia F J Newcombe, Nicholas J Ashton, Jussi P Posti, Ben Glocker, Anne Manktelow, Edward Needham

Brain· June 2022

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Ageing is associated with maladaptive immune response and worse outcome after traumatic brain injury.
Federico Moro, Francesca Pischiutta, Anaïs Portet, Edward J Needham, Emma J Norton

Brain Commun· February 2022

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Safety and efficacy of bexarotene in patients with relapsing-remitting multiple sclerosis (CCMR One): a randomised, double-blind, placebo-controlled, parallel-group, phase 2a study.
J William L Brown, Nick G Cunniffe, Ferran Prados, Baris Kanber, Joanne L Jones, Edward Needham

Lancet Neurol· September 2021

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Mononeuritis multiplex: an unexpectedly frequent feature of severe COVID-19.
Edward Needham, Virginia Newcombe, Andrew Michell, Rachel Thornton, Andrew Grainger

J Neurol· August 2021

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Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury.
Edward J Needham, Oda Stoevesandt, Eric P Thelin, Henrik Zetterberg, Elisa R Zanier

J Immunol· July 2021

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Neurological Implications of COVID-19 Infections.
Edward J Needham, Sherry H-Y Chou, Alasdair J Coles, David K Menon

Neurocrit Care· June 2020

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Keratinocyte growth factor impairs human thymic recovery from lymphopenia.
Alasdair J Coles, Laura Azzopardi, Onajite Kousin-Ezewu, Harpreet Kaur Mullay, Sara Aj Thompson, Edward Needham

JCI Insight· May 2019

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