Publications by authors named "Edward Perez-Reyes"

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Spontaneous Seizure Outcomes in Mice Using an Improved Version of the Pilocarpine Model of Temporal Lobe Epilepsy.
Ronald P Gaykema, Madison J Failor, Aleksandra Maciejczuk, Magda Pikus, Mariia Oliinyk, Edward Perez-Reyes

Int J Mol Sci· September 2025

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Gene therapies alleviate absence epilepsy associated with deficiency in DBA/2J mice.
Zaiyang Zhang, Jingliang Zhang, Xiaoling Chen, Brody A Deming, Shivam Kant, Edward Perez-Reyes

bioRxiv· June 2025

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Preferential superficial cortical layer activation during seizure propagation.
Anastasia Brodovskaya, Shinnosuke Shiono, Chengsan Sun, Edward Perez-Reyes, Jaideep Kapur

Epilepsia· March 2025

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The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.
Stephen P H Alexander, Alistair A Mathie, John A Peters, Emma L Veale, Jörg Striessnig, Edward Perez-Reyes

Br J Pharmacol· October 2023

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EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications.
Cassidy T Burke, Iuliia Vitko, Justyna Straub, Elsa O Nylund, Agnieszka Gawda, Edward Perez-Reyes

Int J Mol Sci· September 2023

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Microglia play beneficial roles in multiple experimental seizure models.
Synphane Gibbs-Shelton, Jordan Benderoth, Ronald P Gaykema, Justyna Straub, Kenneth A Okojie, Edward Perez-Reyes

Glia· July 2023

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Drug-Inducible Gene Therapy Effectively Reduces Spontaneous Seizures in Kindled Rats but Creates Off-Target Side Effects in Inhibitory Neurons.
Kyle A Sullivan, Iuliia Vitko, Kathryn Blair, Ronald P Gaykema, Madison J Failor, Edward Perez-Reyes

Int J Mol Sci· July 2023

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Microglia play beneficial roles in multiple experimental seizure models.
Synphane Shelton-Gibbs, Jordan Benderoth, Ronald P Gaykema, Justyna Straub, Kenneth A Okojie, Edward Perez-Reyes

bioRxiv· March 2023

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AMPK-mediated potentiation of GABAergic signalling drives hypoglycaemia-provoked spike-wave seizures.
Kathryn A Salvati, Matthew L Ritger, Pasha A Davoudian, Finnegan O'Dell, Daniel R Wyskiel, Edward Perez-Reyes

Brain· July 2022

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Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis.
Clint M Upchurch, Scott Yeudall, Caitlin M Pavelec, Dennis Merk, Jan Greulich, Edward Perez-Reyes

Sci Adv· July 2022

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THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels.
Stephen Ph Alexander, Alistair Mathie, John A Peters, Emma L Veale, Jörg Striessnig, Edward Perez-Reyes

Br J Pharmacol· October 2021

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Preparation and Implantation of Electrodes for Electrically Kindling VGAT-Cre Mice to Generate a Model for Temporal Lobe Epilepsy.
Justyna Straub, Iuliia Vitko, Ronald P Gaykema, Edward Perez-Reyes

J Vis Exp· August 2021

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Effect of photobiomodulation on mitochondrial dynamics in peripheral nervous system in streptozotocin-induced type 1 diabetes in rats.
Igor Rafael Correia Rocha, Edward Perez-Reyes, Marucia Chacur

Photochem Photobiol Sci· February 2021

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A brainstem peptide system activated at birth protects postnatal breathing.
Yingtang Shi, Daniel S Stornetta, Robert J Reklow, Alisha Sahu, Yvonne Wabara, Edward Perez-Reyes

Nature· January 2021

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Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy.
Justyna Straub, Agnieszka Gawda, Pranav Ravichandran, Bailey McGrew, Elsa Nylund, Edward Perez-Reyes

Epilepsia· October 2020

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Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy.
Aradhya Nigam, Nicholas J Hargus, Bryan S Barker, Matteo Ottolini, James A Hounshell, Edward Perez-Reyes

Epilepsy Res· August 2019

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Primary aldosteronism associated with a germline variant in .
Kendra Wulczyn, Edward Perez-Reyes, Robert L Nussbaum, Meyeon Park

BMJ Case Rep· May 2019

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LMO7 deficiency reveals the significance of the cuticular plate for hearing function.
Ting-Ting Du, James B Dewey, Elizabeth L Wagner, Runjia Cui, Jinho Heo, Edward Perez-Reyes

Nat Commun· March 2019

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CACHD1 is an α2δ-Like Protein That Modulates Ca3 Voltage-Gated Calcium Channel Activity.
Graeme S Cottrell, Camille H Soubrane, James A Hounshell, Hong Lin, Venetia Owenson, Edward Perez-Reyes

J Neurosci· October 2018

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A novel therapeutic approach for treatment of catamenial epilepsy.
Suchitra Joshi, Huayu Sun, Karthik Rajasekaran, John Williamson, Edward Perez-Reyes

Neurobiol Dis· March 2018

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Calmodulin regulates Ca3 T-type channels at their gating brake.
Jean Chemin, Valentina Taiakina, Arnaud Monteil, Michael Piazza, Wendy Guan, Edward Perez-Reyes

J Biol Chem· December 2017

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Ca Regulation of Ca3.3 T-type Ca Channel Is Mediated by Calmodulin.
Narae Lee, Sua Jeong, Kang-Chang Kim, Jin-Ah Kim, Jin-Yong Park, Edward Perez-Reyes

Mol Pharmacol· September 2017

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Functional variants in and may contribute to genetic generalized epilepsy.
Felicitas Becker, Christopher A Reid, Kerstin Hallmann, Han-Shen Tae, A Marie Phillips, Edward Perez-Reyes

Epilepsia Open· September 2017

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Nalcn Is a "Leak" Sodium Channel That Regulates Excitability of Brainstem Chemosensory Neurons and Breathing.
Yingtang Shi, Chikara Abe, Benjamin B Holloway, Shaofang Shu, Natasha N Kumar, Edward Perez-Reyes

J Neurosci· August 2016

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Central Mechanisms Mediating Thrombospondin-4-induced Pain States.
John Park, Yanhui Peter Yu, Chun-Yi Zhou, Kang-Wu Li, Dongqing Wang, Edward Perez-Reyes

J Biol Chem· June 2016

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