Publications by authors named "Edward Purdue"

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Development of a Janus Kinase Inhibitor Prodrug for the Treatment of Rheumatoid Arthritis.
Xin Wei, Jianbo Wu, Gang Zhao, Josselyn Galdamez, Subodh M Lele, P Edward Purdue

Mol Pharm· August 2018

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HPMA-Copolymer Nanocarrier Targets Tumor-Associated Macrophages in Primary and Metastatic Breast Cancer.
Melissa N Zimel, Chloe B Horowitz, Vinagolu K Rajasekhar, Alexander B Christ, Xin Wei, P Edward Purdue

Mol Cancer Ther· December 2017

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Pharmacokinetic and Biodistribution Studies of HPMA Copolymer Conjugates in an Aseptic Implant Loosening Mouse Model.
Xin Wei, Fei Li, Gang Zhao, Yashpal Singh Chhonker, Christine Averill, P Edward Purdue

Mol Pharm· May 2017

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Nano-analyses of wear particles from metal-on-metal and non-metal-on-metal dual modular neck hip arthroplasty.
Zhidao Xia, Benjamin F Ricciardi, Zhao Liu, Christopher von Ruhland, Mike Ward, Edward Purdue

Nanomedicine· April 2017

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Netrin-1 is highly expressed and required in inflammatory infiltrates in wear particle-induced osteolysis.
Aránzazu Mediero, Bhama Ramkhelawon, Tuere Wilder, P Edward Purdue, Steven R Goldring

Ann Rheum Dis· September 2016

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The Evaluation of Therapeutic Efficacy and Safety Profile of Simvastatin Prodrug Micelles in a Closed Fracture Mouse Model.
Yijia Zhang, Zhenshan Jia, Hongjiang Yuan, Anand Dusad, Ke Ren, P Edward Purdue

Pharm Res· August 2016

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Histopathological characterization of corrosion product associated adverse local tissue reaction in hip implants: a study of 285 cases.
Benjamin F Ricciardi, Allina A Nocon, Seth A Jerabek, Gabrielle Wilner, Elianna Kaplowitz, P Edward Purdue

BMC Clin Pathol· February 2016

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The Evaluation of the Therapeutic Efficacy and Side Effects of a Macromolecular Dexamethasone Prodrug in the Collagen-Induced Arthritis Mouse Model.
Lingdong Quan, Yijia Zhang, Anand Dusad, Ke Ren, P Edward Purdue

Pharm Res· January 2016

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Parthenolide reduces empty lacunae and osteoclastic bone surface resorption induced by polyethylene particles in a murine calvarial model of peri-implant osteolysis.
Muhamad S F Zawawi, Victor Marino, Egon Perilli, Melissa D Cantley, Jiake Xu, P Edward Purdue

J Biomed Mater Res A· November 2015

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Adverse local tissue reaction (ALTR) associated with corrosion products in metal-on-metal and dual modular neck total hip replacements is associated with upregulation of interferon gamma-mediated chemokine signaling.
Kritti Kolatat, Giorgio Perino, Gabrielle Wilner, Elianna Kaplowitz, Benjamin F Ricciardi, P Edward Purdue

J Orthop Res· October 2015

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Effects of steroids on thrombogenic markers in patients undergoing unilateral total knee arthroplasty: a prospective, double-blind, randomized controlled trial.
Alexander S McLawhorn, Jonathan Beathe, Jacques YaDeau, Valeria Buschiazzo, P Edward Purdue

J Orthop Res· March 2015

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Simvastatin prodrug micelles target fracture and improve healing.
Zhenshan Jia, Yijia Zhang, Yen Hsun Chen, Anand Dusad, Hongjiang Yuan, P Edward Purdue

J Control Release· February 2015

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Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate.
P Edward Purdue, Tania N Crotti, Zhenxin Shen, Jennifer Swantek, Jun Li

Sci Rep· December 2014

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Implant based differences in adverse local tissue reaction in failed total hip arthroplasties: a morphological and immunohistochemical study.
Giorgio Perino, Benjamin F Ricciardi, Seth A Jerabek, Guido Martignoni, Gabrielle Wilner, P Edward Purdue

BMC Clin Pathol· September 2014

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Early diagnosis of orthopedic implant failure using macromolecular imaging agents.
Ke Ren, Anand Dusad, Yijia Zhang, P Edward Purdue, Edward V Fehringer

Pharm Res· August 2014

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Aneurysmal bone cysts: denosumab extends its reach.
Edward Purdue

Transl Res· August 2014

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Targeting the giant cell tumor stromal cell: functional characterization and a novel therapeutic strategy.
Matthew R Steensma, Wakenda K Tyler, Allison G Shaber, Steven R Goldring, F Patrick Ross, P Edward Purdue

PLoS One· April 2014

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Elevation of serum tumor necrosis factor α in patients with periprosthetic osteolysis: a case-control study.
R Krishna Chaganti, Edward Purdue, Thomas P Sculco, Lisa A Mandl

Clin Orthop Relat Res· February 2014

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Macromolecular prodrug of dexamethasone prevents particle-induced peri-implant osteolysis with reduced systemic side effects.
Ke Ren, Anand Dusad, Fang Yuan, Hongjiang Yuan, P Edward Purdue

J Control Release· February 2014

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Bone remodelling in inflammatory arthritis.
Steven R Goldring, P Edward Purdue, Tania N Crotti, Zhenxin Shen, Merrilee R Flannery

Ann Rheum Dis· April 2013

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Development of polymeric nanocarrier system for early detection and targeted therapeutic treatment of peri-implant osteolysis.
P Edward Purdue, Adam S Levin, Ke Ren, Thomas P Sculco, Dong Wang

HSS J· February 2013

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Negative regulation of osteoclast precursor differentiation by CD11b and β2 integrin-B-cell lymphoma 6 signaling.
Kyung-Hyun Park-Min, Eun Young Lee, Neal K Moskowitz, Elisha Lim, Sun-Kyeong Lee, P Edward Purdue

J Bone Miner Res· January 2013

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Orthopedic wear debris mediated inflammatory osteolysis is mediated in part by NALP3 inflammasome activation.
Lyndsey Burton, Daniel Paget, Nikolaus B Binder, Krista Bohnert, Bryan J Nestor, P Edward Purdue

J Orthop Res· January 2013

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The effect of TNFα secreted from macrophages activated by titanium particles on osteogenic activity regulated by WNT/BMP signaling in osteoprogenitor cells.
Sang-Soo Lee, Ashish R Sharma, Byung-Soo Choi, Jun-Sub Jung, Jun-Dong Chang, Edward P Purdue

Biomaterials· June 2012

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Early detection and treatment of wear particle-induced inflammation and bone loss in a mouse calvarial osteolysis model using HPMA copolymer conjugates.
Ke Ren, P Edward Purdue, Lyndsey Burton, Ling-dong Quan, Edward V Fehringer

Mol Pharm· August 2011

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