Publications by authors named "Edward Seto"

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Stabilization of RUNX1 Induced by O-GlcNAcylation Promotes PDGF-BB-Mediated Resistance to CDK4/6 Inhibitors in Breast Cancer.
Shuyan Zhou, Yi Zhang, Julie Belmar, Chunyan Hou, Yaqin Zhang, Edward Seto

Cancer Res· May 2025

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TFAP2C-DDR1 axis regulates resistance to CDK4/6 inhibitor in breast cancer.
Muhammad Jameel Mughal, Yi Zhang, Zhuqing Li, Shuyan Zhou, Changmin Peng, Edward Seto

Cancer Lett· February 2025

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Expression of Concern: A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs.
Fengdong Cheng, Maritza Lienlaf, Hong-Wei Wang, Patricio Perez-Villarroel, Calvin Lee, Edward Seto

J Immunol· October 2024

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HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression.
Hongbo Ling, Yixuan Li, Changmin Peng, Shengyu Yang, Edward Seto

NAR Cancer· June 2024

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HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance.
Hongbo Ling, Yixuan Li, Changmin Peng, Shengyu Yang, Edward Seto

bioRxiv· December 2023

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HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis.
Michael F Emmons, Richard L Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Edward Seto

Nat Commun· November 2023

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Retraction Notice to: Coordinated Silencing of MYC-Mediated miR-29 by HDAC3 and EZH2 as a Therapeutic Target of Histone Modification in Aggressive B-Cell Lymphomas.
Xinwei Zhang, Xiaohong Zhao, Warren Fiskus, Jianhong Lin, Tint Lwin, Edward Seto

Cancer Cell· June 2023

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Trapoxin A Analogue as a Selective Nanomolar Inhibitor of HDAC11.
Thanh Tu Ho, Changmin Peng, Edward Seto, Hening Lin

ACS Chem Biol· April 2023

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Reversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling.
Rushita A Bagchi, Emma L Robinson, Tianjing Hu, Ji Cao, Jun Young Hong, Edward Seto

Proc Natl Acad Sci U S A· February 2022

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HDAC11 regulates expression of C/EBPβ and immunosuppressive molecules in myeloid-derived suppressor cells.
Jie Chen, Fengdong Cheng, Eva Sahakian, John Powers, Zi Wang, Edward Seto

J Leukoc Biol· May 2021

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EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function.
Sonali Bahl, Hongbo Ling, Nuwan P N Acharige, Irene Santos-Barriopedro, Mary Kay H Pflum, Edward Seto

Cell Death Dis· May 2021

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Regulation of histone deacetylase activities and functions by phosphorylation and its physiological relevance.
Sonali Bahl, Edward Seto

Cell Mol Life Sci· January 2021

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Lactate production by Staphylococcus aureus biofilm inhibits HDAC11 to reprogramme the host immune response during persistent infection.
Cortney E Heim, Megan E Bosch, Kelsey J Yamada, Amy L Aldrich, Sujata S Chaudhari, Edward Seto

Nat Microbiol· October 2020

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HDAC10 Regulates Cancer Stem-Like Cell Properties in KRAS-Driven Lung Adenocarcinoma.
Yixuan Li, Xiangyang Zhang, Shaoqi Zhu, Eden A Dejene, Weiqun Peng, Edward Seto

Cancer Res· August 2020

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Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation.
Eden A Dejene, Yixuan Li, Zahra Showkatian, Hongbo Ling, Edward Seto

J Biol Chem· July 2020

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Secretome profiling identifies neuron-derived neurotrophic factor as a tumor-suppressive factor in lung cancer.
Ya Zhang, Xuefeng Wu, Yan Kai, Chia-Han Lee, Fengdong Cheng, Edward Seto

JCI Insight· December 2019

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Chromatin regulation by Histone H4 acetylation at Lysine 16 during cell death and differentiation in the myeloid compartment.
Rocio G Urdinguio, Virginia Lopez, Gustavo F Bayón, Rafael Diaz de la Guardia, Marta I Sierra, Edward Seto

Nucleic Acids Res· June 2019

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HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy.
Michael F Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L Messina, Edward Seto

Cancer Res· June 2019

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Emerging roles of histone modifications and HDACs in RNA splicing.
Raneen Rahhal, Edward Seto

Nucleic Acids Res· June 2019

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Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA.
Min Hu, Najealicka Armstrong, Edward Seto, Wenwei Li, Fanxiu Zhu

J Virol· April 2019

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HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2.
Ji Cao, Lei Sun, Pornpun Aramsangtienchai, Nicole A Spiegelman, Xiaoyu Zhang, Edward Seto

Proc Natl Acad Sci U S A· March 2019

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HDAC8 affects MGMT levels in glioblastoma cell lines interaction with the proteasome receptor ADRM1.
Irene Santos-Barriopedro, Yixuan Li, Sonali Bahl, Edward Seto

Genes Cancer· January 2019

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Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication.
Hongbo Ling, Lirong Peng, Jianbo Wang, Raneen Rahhal, Edward Seto

Cell Rep· December 2018

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Loss of HDAC11 ameliorates clinical symptoms in a multiple sclerosis mouse model.
Lei Sun, Elphine Telles, Molly Karl, Fengdong Cheng, Noreen Luetteke, Edward Seto

Life Sci Alliance· October 2018

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HDAC11 suppresses the thermogenic program of adipose tissue via BRD2.
Rushita A Bagchi, Bradley S Ferguson, Matthew S Stratton, Tianjing Hu, Maria A Cavasin, Edward Seto

JCI Insight· August 2018

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