Publications by authors named "Edward W Roberts"

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Epithelial Memory After Respiratory Viral Infection in Mice Results in Prolonged Enhancement of Antigen Presentation.
Piotr P Janas, Wouter T'Jonck, Matthew O Burgess, Maximilian Reck, Caroline Chauché, Edward W Roberts

Allergy· September 2025

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UNC119 regulates T-cell receptor signalling in primary T cells and T acute lymphocytic leukaemia.
Youhani Samarakoon, Tamas Yelland, Esther Garcia-Gonzalez, Amauri da Silva Justo Junior, Mahnoor Mahmood, Edward W Roberts

Life Sci Alliance· March 2025

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Remodelling of the immune landscape by IFNγ counteracts IFNγ-dependent tumour escape in mouse tumour models.
Vivian W C Lau, Gracie J Mead, Zofia Varyova, Julie M Mazet, Anagha Krishnan, Edward W Roberts

Nat Commun· January 2025

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Lung influenza virus-specific memory CD4 T cell location and optimal cytokine production are dependent on interactions with lung antigen-presenting cells.
Kerrie E Hargrave, Julie C Worrell, Chiara Pirillo, Euan Brennan, Andreu Masdefiol Garriga, Edward W Roberts

Mucosal Immunol· October 2024

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CK2 phosphorylation of CMTR1 promotes RNA cap formation and influenza virus infection.
Radoslaw Lukoszek, Francisco Inesta-Vaquera, Natasha J M Brett, Shang Liang, Lydia A Hepburn, Edward W Roberts

Cell Rep· July 2024

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Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma.
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Edward W Roberts

Nat Cancer· April 2024

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De novo priming: driver of immunotherapy responses or epiphenomenon?
Alexander L Young, Tara Lorimer, Sarwah K Al-Khalidi, Edward W Roberts

Essays Biochem· September 2023

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Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade.
Mahnoor Mahmood, Eric Minwei Liu, Amy L Shergold, Elisabetta Tolla, Jacqueline Tait-Mulder, Edward W Roberts

bioRxiv· March 2023

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Fluorogenic Granzyme A Substrates Enable Real-Time Imaging of Adaptive Immune Cell Activity.
Zhiming Cheng, Emily J Thompson, Lorena Mendive-Tapia, Jamie I Scott, Sam Benson, Edward W Roberts

Angew Chem Int Ed Engl· February 2023

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Fluorogenic Granzyme A Substrates Enable Real-Time Imaging of Adaptive Immune Cell Activity.
Zhiming Cheng, Emily J Thompson, Lorena Mendive-Tapia, Jamie I Scott, Sam Benson, Edward W Roberts

Angew Chem Weinheim Bergstr Ger· February 2023

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Impact of protein identity on tumor-associated antigen uptake into infiltrating immune cells: A comparison of different fluorescent proteins as model antigens.
Rulan Yi, Emily Chen, Edward W Roberts, Matthew F Krummel, Nina Kathrin Serwas

PLoS One· August 2022

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Think global but act local: Tuning the dendritic cell response in cancer.
Alberto Bravo-Blas, Chiara Pirillo, Amy Shergold, Anna Andrusaite, Edward W Roberts

Int J Biochem Cell Biol· June 2022

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A fluorogenic probe for granzyme B enables in-biopsy evaluation and screening of response to anticancer immunotherapies.
Jamie I Scott, Lorena Mendive-Tapia, Doireann Gordon, Nicole D Barth, Emily J Thompson, Edward W Roberts

Nat Commun· May 2022

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CXCR2 inhibition enables NASH-HCC immunotherapy.
Jack Leslie, John B G Mackey, Thomas Jamieson, Erik Ramon-Gil, Thomas M Drake, Edward W Roberts

Gut· April 2022

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Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells.
Megan K Ruhland, Edward W Roberts, En Cai, Adriana M Mujal, Kyle Marchuk

Cancer Cell· June 2020

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Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4 T Cell Immunity.
Mikhail Binnewies, Adriana M Mujal, Joshua L Pollack, Alexis J Combes, Emily A Hardison, Edward W Roberts

Cell· April 2019

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Stromal Cells in the Tumor Microenvironment.
Alice E Denton, Edward W Roberts, Douglas T Fearon

Adv Exp Med Biol· February 2019

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Chimeric antigen receptors that trigger phagocytosis.
Meghan A Morrissey, Adam P Williamson, Adriana M Steinbach, Edward W Roberts, Nadja Kern

Elife· June 2018

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Understanding the tumor immune microenvironment (TIME) for effective therapy.
Mikhail Binnewies, Edward W Roberts, Kelly Kersten, Vincent Chan, Douglas F Fearon

Nat Med· May 2018

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Control of an Unusual Photo-Claisen Rearrangement in Coumarin Caged Tamoxifen through an Extended Spacer.
Pamela T Wong, Edward W Roberts, Shengzhuang Tang, Jhindan Mukherjee, Jayme Cannon

ACS Chem Biol· April 2017

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Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity.
Thomas R Flint, Tobias Janowitz, Claire M Connell, Edward W Roberts, Alice E Denton

Cell Metab· November 2016

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Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma.
Edward W Roberts, Miranda L Broz, Mikhail Binnewies, Mark B Headley, Amanda E Nelson

Cancer Cell· August 2016

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Visualization of immediate immune responses to pioneer metastatic cells in the lung.
Mark B Headley, Adriaan Bins, Alyssa Nip, Edward W Roberts, Mark R Looney

Nature· March 2016

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Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells.
Alice E Denton, Edward W Roberts, Michelle A Linterman, Douglas T Fearon

Proc Natl Acad Sci U S A· August 2014

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