Publications by authors named "Edwin A Clark"

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Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Adriana E Tron, Matthew A Belmonte, Ammar Adam, Brian M Aquila, Lawrence H Boise, Edwin A Clark

Nat Commun· December 2018

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Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.
Toni K Choueiri, Elizabeth Plimack, Hendrik-Tobias Arkenau, Eric Jonasch, Daniel Y C Heng, Edwin A Clark

J Clin Oncol· September 2017

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The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient-Derived Xenograft Models.
Alwin G Schuller, Evan R Barry, Rhys D O Jones, Ryan E Henry, Melanie M Frigault, Edwin A Clark

Clin Cancer Res· June 2015

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Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.
Clay L Efferson, Christopher T Winkelmann, Christopher Ware, Timothy Sullivan, Saverio Giampaoli, Edwin A Clark

Cancer Res· March 2010

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Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab.
Shirin Khambata-Ford, Christopher R Garrett, Neal J Meropol, Mark Basik, Christopher T Harbison, Edwin A Clark

J Clin Oncol· August 2007

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Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib.
Alan Serrels, Iain R J Macpherson, T R Jeffry Evans, Francis Y Lee, Edwin A Clark

Mol Cancer Ther· December 2006

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Gene expression profiles predict early relapse in ovarian cancer after platinum-paclitaxel chemotherapy.
Lynn C Hartmann, Karen H Lu, Gerald P Linette, William A Cliby, Kimberly R Kalli, Edwin A Clark

Clin Cancer Res· March 2005

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Total RNA yield and microarray gene expression profiles from fine-needle aspiration biopsy and core-needle biopsy samples of breast carcinoma.
W Fraser Symmans, Mark Ayers, Edwin A Clark, James Stec, Kenneth R Hess

Cancer· June 2003

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