Publications by authors named "Edwin A Yates"

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Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Julia A Tree, Jeremy E Turnbull, Karen R Buttigieg, Michael J Elmore, Naomi Coombes, John Hogwood, Courtney J Mycroft-West, Marcelo A Lima, Mark A Skidmore, Richard Karlsson

Br J Pharmacol· February 2021

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Dietary substances and their glucuronides: structures, occurrence and biological activity.
Andrew V Stachulski, Edwin A Yates, Aleksandra Teriosina, Lesley Hoyles, Simon McArthur

Nat Prod Rep· December 2025

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Arylsulfamates inhibit colonic Bacteroidota growth through a sulfatase-independent mechanism.
Conor J Crawford, Charles W E Tomlinson, Christian Gunawan, Zongjia Chen, Dominic P Byrne, Edwin A Yates

Proc Natl Acad Sci U S A· July 2025

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Involvement of GTPases and vesicle adapter proteins in Heparan sulfate biosynthesis: role of Rab1A, Rab2A and GOLPH3.
Maria C Z Meneghetti, Renan P Cavalheiro, Edwin A Yates, Helena B Nader, Marcelo A Lima

FEBS J· May 2025

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Bacterial polysaccharide lyase family 33: Specificity from an evolutionarily conserved binding tunnel.
Mélanie Loiodice, Elodie Drula, Zak McIver, Svetlana Antonyuk, Arnaud Baslé, Edwin A Yates

Proc Natl Acad Sci U S A· February 2025

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Detection of β-D-glucuronidase activity in environmental samples using 4-fluorophenyl β-D-glucuronide and F NMR.
Aleksandra Teriosina, Igor L Barsukov, Alan Cartmell, Andrew K Powell, Andrew V Stachulski, Edwin A Yates

Anal Methods· February 2025

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Modeling the Detailed Conformational Effects of the Lactosylation of Hyaluronic Acid.
Stefano Elli, Tommaso Sisto, Sofia Nizzolo, Nadia Freato, Laura Bertocchi, Edwin A Yates

Biomacromolecules· January 2025

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Synthetic β-d-Glucuronides: Substrates for Exploring Glucuronide Degradation by Human Gut Bacteria.
Aleksandra Gorecka, Heidi Schacht, Megan K Fraser, Aleksandra Teriosina, James A London, Edwin A Yates

ACS Omega· January 2025

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Interactions of proteins with heparan sulfate.
Faizah S Alotaibi, Marim M R Alsadun, Sarah A Alsaiari, Krithika Ramakrishnan, Edwin A Yates

Essays Biochem· December 2024

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Polysaccharide sulfotransferases: the identification of putative sequences and respective functional characterisation.
Ravina Mistry, Dominic P Byrne, David Starns, Igor L Barsukov, Edwin A Yates

Essays Biochem· December 2024

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Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility.
Jurij Froese, Marco Mandalari, Monica Civera, Stefano Elli, Isabel Pagani, Edwin A Yates

Sci Rep· December 2024

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Differential Solvent DEEP-STD NMR and MD Simulations Enable the Determinants of the Molecular Recognition of Heparin Oligosaccharides by Antithrombin to Be Disentangled.
Michela Parafioriti, Stefano Elli, Juan C Muñoz-García, Jonathan Ramírez-Cárdenas, Edwin A Yates

Int J Mol Sci· April 2024

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Low sulfated heparan sulfate mimetic differentially affects repair in immune-mediated and toxin-induced experimental models of demyelination.
Susan L Lindsay, George A McCanney, Jiangshan Zhan, Miriam Scheld, Rebecca Sherrard Smith, Edwin A Yates

Glia· July 2023

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Monitoring the stability of heparin: NMR evidence for the rearrangement of sulfated iduronate in phosphate buffer.
Aleksandra M Kozlowski, Edwin A Yates, Johannes P Roubroeks, Kristoffer Tømmeraas, Flemming H Larsen

Carbohydr Polym· May 2023

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Functions and specificity of bacterial carbohydrate sulfatases targeting host glycans.
Ana S Luis, Edwin A Yates, Alan Cartmell

Essays Biochem· April 2023

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A sulphated glycosaminoglycan extract from Placopecten magellanicus inhibits the Alzheimer's disease β-site amyloid precursor protein cleaving enzyme 1 (BACE-1).
Courtney J Mycroft-West, Anthony J Devlin, Lynsay C Cooper, Scott E Guimond, Patricia Procter, Edwin A Yates

Carbohydr Res· March 2023

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High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts.
Marissa L Maciej-Hulme, Anaëlle C N Leprince, Andre Lavin, Scott E Guimond, Jeremy E Turnbull, Edwin A Yates

Anal Methods· March 2023

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Analysis of Heparin Samples by Attenuated Total Reflectance Fourier-Transform Infrared Spectroscopy in the Solid State.
Anthony J Devlin, Courtney J Mycroft-West, Jeremy E Turnbull, Marcelo Andrade de Lima, Marco Guerrini, Edwin A Yates

ACS Cent Sci· March 2023

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Validation of Recombinant Heparan Sulphate Reagents for CNS Repair.
Susan L Lindsay, Rebecca Sherrard Smith, Edwin A Yates, Colin Cartwright, Bryan E Thacker

Biology (Basel)· March 2023

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Evidence for Multiple Binding Modes in the Initial Contact Between SARS-CoV-2 Spike S1 Protein and Cell Surface Glycans.
Michela Parafioriti, Minghong Ni, Maurice Petitou, Courtney J Mycroft-West, Timothy R Rudd, Edwin A Yates

Chemistry· January 2023

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Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors.
Anna L Gray, Richard Karlsson, Abigail R E Roberts, Amanda J L Ridley, Nabina Pun, Edwin A Yates

Cell Rep· January 2023

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Heparin Protects Human Neural Progenitor Cells from Zika Virus-Induced Cell Death While Preserving Their Differentiation into Mature Neuroglial Cells.
Isabel Pagani, Linda Ottoboni, Paola Podini, Silvia Ghezzi, Elena Brambilla, Edwin A Yates

J Virol· October 2022

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Author Correction: Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota.
Ana S Luis, Arnaud Baslé, Dominic P Byrne, Gareth S A Wright, James A London, Edwin A Yates

Nat Chem Biol· September 2022

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Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota.
Ana S Luis, Arnaud Baslé, Dominic P Byrne, Gareth S A Wright, James A London, Edwin A Yates

Nat Chem Biol· August 2022

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Using NMR to Dissect the Chemical Space and -Sulfation Effects within the - and -Glycoside Analogues of Heparan Sulfate.
Maria C Z Meneghetti, Lucy Naughton, Conor O'Shea, Dindet S-E Koffi Teki, Vincent Chagnault, Edwin A Yates

ACS Omega· July 2022

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Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction.
Scott E Guimond, Courtney J Mycroft-West, Neha S Gandhi, Julia A Tree, Thuy T Le, Edwin A Yates

ACS Cent Sci· May 2022

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