Publications by authors named "Edwin Rock"

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3D-printed plugs enhance cell usage efficiency for single-cell migration and neuron axon guidance assays.
Jinxiong Cheng, Edwin C Rock, Mishal Rao, Hsiao-Chun Chen, Yushu Ma

Cell Rep Methods· August 2025

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Inhibiting CXCR4 reduces immunosuppressive effects of myeloid cells in breast cancer immunotherapy.
Nicholas G Ciavattone, Avinash Bevoor, Alex Farfel, Aasia Rehman, Kenneth K Y Ho, Edwin C Rock, Brock A Humphries

Sci Rep· February 2025

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Deep learning unlocks label-free viability assessment of cancer spheroids in microfluidics.
Chun-Cheng Chiang, Rajiv Anne, Pooja Chawla, Rachel M Shaw, Sarah He, Edwin C Rock

Lab Chip· June 2024

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Selectins in Biology and Human Disease: Opportunity in E-selectin Antagonism.
John M Peterson, Theodore A Smith, Edwin P Rock, John L Magnani

Cureus· June 2024

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Adverse Drug Reaction vs Care Complication: Response to "Use of Colony-Stimulating Factors in Patients With Systemic Lupus Erythematous".
Carolyn E Ragsdale, Edwin P Rock

J Pharm Pract· April 2024

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Single-cell morphological and transcriptome analysis unveil inhibitors of polyploid giant breast cancer cells in vitro.
Mengli Zhou, Yushu Ma, Chun-Cheng Chiang, Edwin C Rock, Samuel Charles Butler

Commun Biol· December 2023

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Real-world outcomes of 18,186 metastatic solid tumor outpatients: Baseline blood cell counts correlate with survival after immune checkpoint inhibitor therapy.
Jerome H Goldschmidt, Lin-Na Chou, Philip K Chan, Liwei Chen, Nicholas Robert, Edwin P Rock

Cancer Med· November 2023

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Microfluidic single-cell migration chip reveals insights into the impact of extracellular matrices on cell movement.
Mengli Zhou, Yushu Ma, Edwin C Rock, Chun-Cheng Chiang, Kathryn E Luker

Lab Chip· October 2023

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High-Throughput Cellular Heterogeneity Analysis in Cell Migration at the Single-Cell Level.
Mengli Zhou, Yushu Ma, Chun-Cheng Chiang, Edwin C Rock, Kathryn E Luker

Small· February 2023

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Utility of monocyte HLA-DR and rationale for therapeutic GM-CSF in sepsis immunoparalysis.
Ila Joshi, Walter P Carney, Edwin P Rock

Front Immunol· February 2023

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Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders.
Hillard M Lazarus, Katherine Pitts, Tisha Wang, Elinor Lee, Elizabeth Buchbinder, Edwin P Rock

Front Immunol· January 2023

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Role of Fcγ receptors in HER2-targeted breast cancer therapy.
Antonino Musolino, William J Gradishar, Hope S Rugo, Jeffrey L Nordstrom, Edwin P Rock

J Immunother Cancer· January 2022

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Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial.
Hope S Rugo, Seock-Ah Im, Fatima Cardoso, Javier Cortés, Giuseppe Curigliano, Edwin P Rock

JAMA Oncol· April 2021

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A First-in-Human Phase I Study of OPB-111077, a Small-Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers.
Anthony Tolcher, Keith Flaherty, Geoffrey I Shapiro, Jordan Berlin, Thomas Witzig, Edwin Rock

Oncologist· June 2018

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Guadecitabine (SGI-110) in treatment-naive patients with acute myeloid leukaemia: phase 2 results from a multicentre, randomised, phase 1/2 trial.
Hagop M Kantarjian, Gail J Roboz, Patricia L Kropf, Karen W L Yee, Casey L O'Connell, Edwin P Rock

Lancet Oncol· October 2017

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Dosing algorithm revisit for busulfan following IV infusion.
Yanlin Wang, Kazunobu Kato, Christopher Le Gallo, Elizabeth Armstrong, Edwin Rock

Cancer Chemother Pharmacol· March 2015

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Phase 1, open-label, dose-escalation, and pharmacokinetic study of STAT3 inhibitor OPB-31121 in subjects with advanced solid tumors.
Johanna C Bendell, David S Hong, Howard A Burris, Aung Naing, Suzanne F Jones, Edwin P Rock, Razelle Kurzrock

Cancer Chemother Pharmacol· July 2014

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Refining endpoints in brain tumor clinical trials.
Christina A Meyers, Edwin P Rock, Howard A Fine

J Neurooncol· June 2012

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GCP data quality for early clinical development.
Edwin P Rock, Vernette J Molloy, Jeffrey S Humphrey

Clin Cancer Res· March 2010

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Assessing proarrhythmic potential of drugs when optimal studies are infeasible.
Edwin P Rock, John Finkle, Howard J Fingert, Brian P Booth, Christine E Garnett

Am Heart J· May 2009

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Lenalidomide in combination with dexamethasone for the treatment of multiple myeloma after one prior therapy.
Maitreyee Hazarika, Edwin Rock, Gene Williams, Ramzi Dagher, Rajeshwari Sridhara

Oncologist· October 2008

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Challenges to use of health-related quality of life for Food and Drug Administration approval of anticancer products.
Edwin P Rock, Jane A Scott, Dianne L Kennedy, Rajeshwari Sridhara, Richard Pazdur

J Natl Cancer Inst Monogr· December 2007

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Patient-reported outcomes to support medical product labeling claims: FDA perspective.
Donald L Patrick, Laurie B Burke, John H Powers, Jane A Scott, Edwin P Rock

Value Health· December 2007

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Patient-reported outcomes supporting anticancer product approvals.
Edwin P Rock, Dianne L Kennedy, Melissa H Furness, William F Pierce, Richard Pazdur

J Clin Oncol· November 2007

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Patient-reported outcomes assessment in cancer trials: taking stock, moving forward.
Joseph Lipscomb, Bryce B Reeve, Steven B Clauser, Jeffrey S Abrams, Deborah Watkins Bruner, Edwin P Rock

J Clin Oncol· November 2007

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