Publications by authors named "Efthymios Motakis"

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TEAL-Seq: targeted expression analysis sequencing.
Georgia Doing, Priya Shanbhag, Isaac Bell, Sara Cassidy, Efthymios Motakis

mSphere· May 2025

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Single-cell decoding of human islet cell type-specific alterations in type 2 diabetes reveals converging genetic- and state-driven -cell gene expression defects.
Khushdeep Bandesh, Efthymios Motakis, Siddhi Nargund, Romy Kursawe, Vijay Selvam

bioRxiv· January 2025

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Computationally defined and in vitro validated putative genomic safe harbour loci for transgene expression in human cells.
Matias I Autio, Efthymios Motakis, Arnaud Perrin, Talal Bin Amin, Zenia Tiang

Elife· January 2024

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Myocardial Biomechanics and the Consequent Differentially Expressed Genes of the Left Atrial Ligation Chick Embryonic Model of Hypoplastic Left Heart Syndrome.
S Samaneh Lashkarinia, Wei Xuan Chan, Efthymios Motakis, Sheldon Ho, Hummaira Banu Siddiqui

Ann Biomed Eng· May 2023

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Bronchial epithelium epithelial-mesenchymal plasticity forms aberrant basaloid-like cells in vitro.
Dinesh Babu Uthaya Kumar, Efthymios Motakis, Marina Yurieva, Vivek Kohar, Jan Martinek

Am J Physiol Lung Cell Mol Physiol· June 2022

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Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia.
Sharmelee Selvaraji, Motakis Efthymios, Roger Sik Yin Foo, David Y Fann, Mitchell Kim Peng Lai

Theranostics· May 2022

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Effects of extended pharmacological disruption of zebrafish embryonic heart biomechanical environment on cardiac function, morphology, and gene expression.
Yoke Yin Foo, Efthymios Motakis, Zenia Tiang, Shuhao Shen, Jason Kuan Han Lai

Dev Dyn· December 2021

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Dimethyl sulfoxide (DMSO) enhances direct cardiac reprogramming by inhibiting the bromodomain of coactivators CBP/p300.
Choon Kiat Lim, Motakis Efthymios, Wilson Tan, Matias Ilmari Autio, Zenia Tiang

J Mol Cell Cardiol· November 2021

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Prioritizing Candidates of Post-Myocardial Infarction Heart Failure Using Plasma Proteomics and Single-Cell Transcriptomics.
Mark Y Chan, Motakis Efthymios, Sock Hwee Tan, John W Pickering, Richard Troughton

Circulation· October 2020

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A pragmatic randomised controlled trial of preferred intensity exercise in depressed adult women in the United Kingdom: secondary analysis of individual variability of depression.
Ioannis D Morres, Anton Hinton-Bayre, Efthymios Motakis, Tim Carter, Patrick Callaghan

BMC Public Health· July 2019

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Robust CTCF-Based Chromatin Architecture Underpins Epigenetic Changes in the Heart Failure Stress-Gene Response.
Dominic Paul Lee, Wilson Lek Wen Tan, Chukwuemeka George Anene-Nzelu, Chang Jie Mick Lee, Peter Yiqing Li, Motakis Efthymios

Circulation· April 2019

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C1 CAGE detects transcription start sites and enhancer activity at single-cell resolution.
Tsukasa Kouno, Jonathan Moody, Andrew Tae-Jun Kwon, Youtaro Shibayama, Sachi Kato, Efthymios Motakis

Nat Commun· January 2019

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Sense-antisense gene-pairs in breast cancer and associated pathological pathways.
Oleg V Grinchuk, Efthymios Motakis, Surya Pavan Yenamandra, Ghim Siong Ow, Piroon Jenjaroenpun

Oncotarget· December 2015

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Retinoic acid potentiates inflammatory cytokines in human mast cells: identification of mast cells as prominent constituents of the skin retinoid network.
Magda Babina, Sven Guhl, Efthymios Motakis, Metin Artuc, Tarek Hazzan

Mol Cell Endocrinol· May 2015

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Mast cell transcriptome elucidation: what are the implications for allergic disease in the clinic and where do we go next?
Magda Babina, Efthymios Motakis, Torsten Zuberbier

Expert Rev Clin Immunol· August 2014

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Redefinition of the human mast cell transcriptome by deep-CAGE sequencing.
Efthymios Motakis, Sven Guhl, Yuri Ishizu, Masayoshi Itoh, Hideya Kawaji

Blood· April 2014

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A promoter-level mammalian expression atlas.

Nature· March 2014

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deltaGseg: macrostate estimation via molecular dynamics simulations and multiscale time series analysis.
Diana H P Low, Efthymios Motakis

Bioinformatics· October 2013

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