Publications by authors named "Eilyn Lacy"

Claim this Profile
G
Guselkumab binding to CD64 IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling.
Kacey L Sachen, Deepa Hammaker, Indra Sarabia, Brian Stoveken, John Hartman, Eilyn R Lacy

Front Immunol· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel label-free method to determine equilibrium dissociation constants of antibodies binding to cell surface proteins.
Eilyn R Lacy, Rupesh Nanjunda, Scott L Klakamp, Deborah Kwok, Jennifer F Nemeth

Sci Rep· January 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Peter T Buckley, Rita Chan, Jeffrey Fernandez, Jinquan Luo, Keenan A Lacey, Eilyn R Lacy

Cell Host Microbe· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
"
"Stapling" scFv for multispecific biotherapeutics of superior properties.
Lauren E Boucher, Elisabeth Geyer Prinslow, Michael Feldkamp, Fang Yi, Rupesh Nanjunda, Eilyn R Lacy

MAbs· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis.
Suzanne Edavettal, Pilar Cejudo-Martin, Bidisha Dasgupta, Danlin Yang, Matthew D Buschman, Eilyn Lacy

Med· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
Kristof Van Kolen, Thomas J Malia, Clara Theunis, Rupesh Nanjunda, Alexey Teplyakov, Eilyn Lacy

J Alzheimers Dis· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Pharmacological Profile of JNJ-64179375: A Novel, Long-Acting Exosite-1 Thrombin Inhibitor.
Zheng Huang Devine, Fuyong Du, Qiu Li, Matthew Bunce, Eilyn R Lacy

J Pharmacol Exp Ther· November 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Anti-Tau Monoclonal Antibodies Derived from Soluble and Filamentous Tau Show Diverse Functional Properties in vitro and in vivo.
Marc Vandermeeren, Marianne Borgers, Kristof Van Kolen, Clara Theunis, Bruno Vasconcelos, Eilyn Lacy

J Alzheimers Dis· July 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Human IgG subclass cross-species reactivity to mouse and cynomolgus monkey Fcγ receptors.
Mehabaw G Derebe, Rupesh K Nanjunda, Gary L Gilliland, Eilyn R Lacy, Mark L Chiu

Immunol Lett· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
U
Unique pharmacology of a novel allosteric agonist/sensitizer insulin receptor monoclonal antibody.
Simon A Hinke, Anne M Cieniewicz, Thomas Kirchner, Katharine D'Aquino, Rupesh Nanjunda, Eilyn R Lacy

Mol Metab· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
N
Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance.
Anne M Cieniewicz, Thomas Kirchner, Simon A Hinke, Rupesh Nanjunda, Katharine D'Aquino, Eilyn R Lacy

Diabetes· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Monoclonal antibodies targeting ST2L Domain 1 or Domain 3 differentially modulate IL-33-induced cytokine release by human mast cell and basophilic cell lines.
Natalie Fursov, Jin Lu, Catherine Healy, Sheng-Jiun Wu, Eilyn Lacy

Mol Immunol· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Epitope mapping and structural basis for the recognition of phosphorylated tau by the anti-tau antibody AT8.
Thomas J Malia, Alexey Teplyakov, Robin Ernst, Sheng-Jiun Wu, Eilyn R Lacy

Proteins· April 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CCL22-specific Antibodies Reveal That Engagement of Two Distinct Binding Domains on CCL22 Is Required for CCR4-mediated Function.
Sandra Santulli-Marotto, John Wheeler, Eilyn R Lacy, Ken Boakye, Jennifer Luongo

Monoclon Antib Immunodiagn Immunother· December 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Impact of Cell-surface Antigen Expression on Target Engagement and Function of an Epidermal Growth Factor Receptor × c-MET Bispecific Antibody.
Stephen W Jarantow, Barbara S Bushey, Jose R Pardinas, Ken Boakye, Eilyn R Lacy

J Biol Chem· October 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α.
David J Shealy, Ann Cai, Kim Staquet, Audrey Baker, Eilyn R Lacy

MAbs· April 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Engagement of two distinct binding domains on CCL17 is required for signaling through CCR4 and establishment of localized inflammatory conditions in the lung.
Sandra Santulli-Marotto, Ken Boakye, Eilyn Lacy, Sheng-Jiun Wu, Jennifer Luongo

PLoS One· March 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Isolation and optimization for affinity and biophysical characteristics of anti-CCL17 antibodies from the VH1-69 germline gene.
John W Kehoe, Brian Whitaker, Deidra Bethea, Eilyn R Lacy, Ken Boakye

Protein Eng Des Sel· June 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations.
Omid Vafa, Gary L Gilliland, Randall J Brezski, Brandy Strake, Teresa Wilkinson, Eilyn R Lacy

Methods· January 2014

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mechanisms of self-association of a human monoclonal antibody CNTO607.
Deidra Bethea, Sheng-Jiun Wu, Jinquan Luo, Linus Hyun, Eilyn R Lacy

Protein Eng Des Sel· October 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Characterization of neutralizing affinity-matured human respiratory syncytial virus F binding antibodies in the sub-picomolar affinity range.
Gabriela A Canziani, Jose A Melero, Eilyn R Lacy

J Mol Recognit· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Equilibrium and kinetic analysis of human interleukin-13 and IL-13 receptor alpha-2 complex formation.
Eilyn R Lacy

J Mol Recognit· March 2012

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structural basis for the dual recognition of IL-12 and IL-23 by ustekinumab.
Jinquan Luo, Sheng-Jiun Wu, Eilyn R Lacy, Yevgeniya Orlovsky, Audrey Baker

J Mol Biol· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-based engineering of a monoclonal antibody for improved solubility.
Sheng-Jiun Wu, Jinquan Luo, Karyn T O'Neil, James Kang, Eilyn R Lacy

Protein Eng Des Sel· August 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Free sulfhydryl measurement as an indicator of antibody stability.
Eilyn R Lacy, Margaret Baker, Michael Brigham-Burke

Anal Biochem· November 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis