Publications by authors named "Ekram Gad"

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Systemically administered low-affinity HER2 CAR T cells mediate antitumor efficacy without toxicity.
Tamer Basel Shabaneh, Andrew R Stevens, Sylvia M Stull, Kristen R Shimp, Brandon W Seaton, Ekram A Gad

J Immunother Cancer· February 2024

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Anti-tumor activity of a T-helper 1 multiantigen vaccine in a murine model of prostate cancer.
Denise L Cecil, Benjamin Curtis, Ekram Gad, Michael Gormley, Andrew E Timms

Sci Rep· August 2022

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COX-2 Inhibitors Decrease Expression of PD-L1 in Colon Tumors and Increase the Influx of Type I Tumor-infiltrating Lymphocytes.
Denise L Cecil, Ekram A Gad, Lauren R Corulli, Nicholas Drovetto, Ronald A Lubet

Cancer Prev Res (Phila)· April 2022

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Multi-Epitope-Based Vaccines for Colon Cancer Treatment and Prevention.
Lauren R Corulli, Denise L Cecil, Ekram Gad, Marlese Koehnlein, Andrew L Coveler

Front Immunol· December 2021

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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients.
Sasha E Stanton, Ekram Gad, Erik Ramos, Lauren Corulli, James Annis

NPJ Breast Cancer· May 2021

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Therapeutic and Prophylactic Antitumor Activity of an Oral Inhibitor of Fucosylation in Spontaneous Mammary Cancers.
Mary L Disis, Lauren R Corulli, Ekram A Gad, Marlese R Koehnlein, Denise L Cecil

Mol Cancer Ther· May 2020

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The Effect of Mouse Strain, Sex, and Carcinogen Dose on Toxicity and the Development of Lung Dysplasia and Squamous Cell Carcinomas in Mice.
Laura Riolobos, Ekram A Gad, Piper M Treuting, Andrew E Timms, Elliot A Hershberg

Cancer Prev Res (Phila)· August 2019

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Tumor-associated antigens identified early in mouse mammary tumor development can be effective vaccine targets.
Sasha E Stanton, Ekram Gad, Lauren R Corulli, Hailing Lu, Mary L Disis

Vaccine· June 2019

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Immunization against HIF-1α Inhibits the Growth of Basal Mammary Tumors and Targets Mammary Stem Cells .
Denise L Cecil, Meredith Slota, Megan M O'Meara, Benjamin C Curtis, Ekram Gad

Clin Cancer Res· July 2017

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Epidermal growth factor receptor derived peptide vaccination to prevent lung adenocarcinoma formation: An in vivo study in a murine model of EGFR mutant lung cancer.
Johnathan D Ebben, Ronald A Lubet, Ekram Gad, Mary L Disis, Ming You

Mol Carcinog· November 2016

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The Antitumor Efficacy of IL2/IL21-Cultured Polyfunctional Neu-Specific T Cells Is TNFα/IL17 Dependent.
Vy Phan-Lai, Yushe Dang, Ekram Gad, Jennifer Childs, Mary L Disis

Clin Cancer Res· May 2016

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Preservation of tumor-host immune interactions with luciferase-tagged imaging in a murine model of ovarian cancer.
John B Liao, Kelsie J Ovenell, Erin E M Curtis, Denise L Cecil, Marlese R Koehnlein, Ekram A Gad

J Immunother Cancer· May 2015

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Natural history of tumor growth and immune modulation in common spontaneous murine mammary tumor models.
Ekram Gad, Lauren Rastetter, Meredith Slota, Marlese Koehnlein, Piper M Treuting

Breast Cancer Res Treat· December 2014

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Protein-bound polysaccharide-K induces IL-1β via TLR2 and NLRP3 inflammasome activation.
Yi Yang, Carol Inatsuka, Ekram Gad, Mary L Disis, Leanna J Standish

Innate Immun· November 2014

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Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity.
Denise L Cecil, Gregory E Holt, Kyong Hwa Park, Ekram Gad, Lauren Rastetter

Cancer Res· May 2014

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Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer.
Jianning Mao, Jon Ladd, Ekram Gad, Lauren Rastetter, Melissa M Johnson

J Transl Med· May 2014

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Protein-bound polysaccharide activates dendritic cells and enhances OVA-specific T cell response as vaccine adjuvant.
Abbi L Engel, Guan-Cheng Sun, Ekram Gad, Lauren R Rastetter, Katie Strobe

Immunobiology· December 2013

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A multiantigen vaccine targeting neu, IGFBP-2, and IGF-IR prevents tumor progression in mice with preinvasive breast disease.
Mary L Disis, Ekram Gad, Daniel R Herendeen, Vy Phan- Lai, Kyong Hwa Park

Cancer Prev Res (Phila)· December 2013

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Gamma delta T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK.
Carol Inatsuka, Yi Yang, Ekram Gad, Lauren Rastetter, Mary L Disis

Cancer Immunol Immunother· August 2013

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T-helper I immunity, specific for the breast cancer antigen insulin-like growth factor-I receptor (IGF-IR), is associated with increased adiposity.
Denise L Cecil, Kyong Hwa Park, Ekram Gad, Jennifer S Childs, Doreen M Higgins

Breast Cancer Res Treat· June 2013

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Three-dimensional scaffolds to evaluate tumor associated fibroblast-mediated suppression of breast tumor specific T cells.
Vy Phan-Lai, Stephen J Florczyk, Forrest M Kievit, Kui Wang, Ekram Gad

Biomacromolecules· May 2013

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Dendritic cell-activating vaccine adjuvants differ in the ability to elicit antitumor immunity due to an adjuvant-specific induction of immunosuppressive cells.
Yushe Dang, Wolfgang M Wagner, Ekram Gad, Lauren Rastetter, Carmen M Berger

Clin Cancer Res· June 2012

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TLR2 agonist PSK activates human NK cells and enhances the antitumor effect of HER2-targeted monoclonal antibody therapy.
Hailing Lu, Yi Yang, Ekram Gad, Carol Inatsuka, Cynthia A Wenner

Clin Cancer Res· November 2011

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Polysaccharide krestin is a novel TLR2 agonist that mediates inhibition of tumor growth via stimulation of CD8 T cells and NK cells.
Hailing Lu, Yi Yang, Ekram Gad, Cynthia A Wenner, Amy Chang

Clin Cancer Res· January 2011

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Treatment failure of a TLR-7 agonist occurs due to self-regulation of acute inflammation and can be overcome by IL-10 blockade.
Hailing Lu, Wolfgang M Wagner, Ekram Gad, Yi Yang, Hangjun Duan

J Immunol· May 2010

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