Publications by authors named "Eleanor Simpson"

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Impact of temporal uncertainty on sign-tracking behavior.
Rie Kaneko, Eleanor H Simpson, Peter D Balsam

J Exp Psychol Anim Learn Cogn· April 2025

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Learning depends on the information conveyed by temporal relationships between events and is reflected in the dopamine response to cues.
Peter D Balsam, Eleanor H Simpson, Kathleen Taylor, Abigail Kalmbach, Charles R Gallistel

Sci Adv· September 2024

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Lights, fiber, action! A primer on in vivo fiber photometry.
Eleanor H Simpson, Thomas Akam, Tommaso Patriarchi, Marta Blanco-Pozo, Lauren M Burgeno

Neuron· March 2024

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Dopamine transporter blockade during adolescence increases adult dopamine function, impulsivity, and aggression.
Deepika Suri, Giulia Zanni, Darshini Mahadevia, Nao Chuhma, Rinki Saha, Eleanor H Simpson

Mol Psychiatry· August 2023

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Dopamine D2 receptors bidirectionally regulate striatal enkephalin expression: Implications for cocaine reward.
Kathy Z Dai, In Bae Choi, Ryan Levitt, Mariah B Blegen, Alanna R Kaplan, Eleanor H Simpson

Cell Rep· September 2022

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A missense mutation in causes hippocampal learning deficits in mice.
Pin Xu, Kazuhiro Shimomura, Changhoon Lee, Xiaofei Gao, Eleanor H Simpson

Proc Natl Acad Sci U S A· August 2022

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Dopamine encodes real-time reward availability and transitions between reward availability states on different timescales.
Abigail Kalmbach, Vanessa Winiger, Nuri Jeong, Arun Asok, Charles R Gallistel, Eleanor H Simpson

Nat Commun· July 2022

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How changes in dopamine D2 receptor levels alter striatal circuit function and motivation.
Eleanor H Simpson, Eduardo F Gallo, Peter D Balsam, Jonathan A Javitch, Christoph Kellendonk

Mol Psychiatry· January 2022

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Emerging roles of striatal dopamine D2 receptors in motivated behaviour: Implications for psychiatric disorders.
Pedro R Olivetti, Peter D Balsam, Eleanor H Simpson, Christoph Kellendonk

Basic Clin Pharmacol Toxicol· June 2020

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Dissociating the effects of dopamine D2 receptors on effort-based versus value-based decision making using a novel behavioral approach.
Matthew R Bailey, Eileen Chun, Elke Schipani, Peter D Balsam, Eleanor H Simpson

Behav Neurosci· April 2020

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Overexpression of striatal D2 receptors reduces motivation thereby decreasing food anticipatory activity.
Joseph LeSauter, Peter D Balsam, Eleanor H Simpson, Rae Silver

Eur J Neurosci· January 2020

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Striatal dopamine D2 receptors regulate effort but not value-based decision making and alter the dopaminergic encoding of cost.
Ina Filla, Matthew R Bailey, Elke Schipani, Vanessa Winiger, Chris Mezias, Eleanor H Simpson

Neuropsychopharmacology· October 2018

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Striatal dopamine 2 receptor upregulation during development predisposes to diet-induced obesity by reducing energy output in mice.
Marie A Labouesse, Andrea M Sartori, Oliver Weinmann, Eleanor H Simpson, Christoph Kellendonk

Proc Natl Acad Sci U S A· October 2018

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Impaired recruitment of dopamine neurons during working memory in mice with striatal D2 receptor overexpression.
Sevil Duvarci, Eleanor H Simpson, Gaby Schneider, Eric R Kandel, Jochen Roeper

Nat Commun· July 2018

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Neuregulin1 modulation of experimental autoimmune encephalomyelitis (EAE).
Elise Allender, Harvinderjeet Deol, Sarah Schram, Kathleen J Maheras, Alexander Gow, Eleanor H Simpson

J Neuroimmunol· May 2018

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Slowing disease progression in the SOD1 mouse model of ALS by blocking neuregulin-induced microglial activation.
Jianguo Liu, Elise Allender, Jiajing Wang, Eleanor H Simpson, Jeffrey A Loeb

Neurobiol Dis· March 2018

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An Interaction between Serotonin Receptor Signaling and Dopamine Enhances Goal-Directed Vigor and Persistence in Mice.
Matthew R Bailey, Olivia Goldman, Estefanía P Bello, Muhammad O Chohan, Nuri Jeong, Eleanor H Simpson

J Neurosci· February 2018

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Insights About Striatal Circuit Function and Schizophrenia From a Mouse Model of Dopamine D Receptor Upregulation.
Eleanor H Simpson, Christoph Kellendonk

Biol Psychiatry· January 2017

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Neural substrates underlying effort, time, and risk-based decision making in motivated behavior.
Matthew R Bailey, Eleanor H Simpson, Peter D Balsam

Neurobiol Learn Mem· September 2016

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The Behavioral Neuroscience of Motivation: An Overview of Concepts, Measures, and Translational Applications.
Eleanor H Simpson, Peter D Balsam

Curr Top Behav Neurosci· July 2016

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The effects of pharmacological modulation of the serotonin 2C receptor on goal-directed behavior in mice.
Matthew R Bailey, Cait Williamson, Chris Mezias, Vanessa Winiger, Rae Silver, Eleanor H Simpson

Psychopharmacology (Berl)· February 2016

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Improving temporal cognition by enhancing motivation.
Billur Avlar, Julia B Kahn, Greg Jensen, Eric R Kandel, Eleanor H Simpson

Behav Neurosci· October 2015

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Correction to Ward et al. (2015).
Ryan D Ward, Vanessa Winiger, Kerin K Higa, Julia B Kahn, Eric R Kandel, Eleanor H Simpson

Behav Neurosci· August 2015

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Orbitofrontal cortex mediates the differential impact of signaled-reward probability on discrimination accuracy.
Ryan D Ward, Vanessa Winiger, Eric R Kandel, Peter D Balsam, Eleanor H Simpson

Front Neurosci· July 2015

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A novel strategy for dissecting goal-directed action and arousal components of motivated behavior with a progressive hold-down task.
Matthew R Bailey, Greg Jensen, Kathleen Taylor, Chris Mezias, Cait Williamson, Eleanor H Simpson

Behav Neurosci· June 2015

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