Publications by authors named "Elisa Toropainen"

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New insights on liposomal formulations based upon tear film lipids: A combined study of safety and ocular surface pharmacokinetics.
Janika Jäntti, Jooseppi Puranen, Arto Merivaara, Anusha Balla, Eveliina Tuomikoski, Elisa Toropainen

Eur J Pharm Sci· December 2025

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Drug release and pharmacokinetics of intravitreal liposomal injections: a case study with cyclic guanosine monophosphate derivative.
Eetu Valkama, Amir Sadeghi, Elisa Toropainen, Oswaldo Perez, Nicolaas Schipper

Eur J Pharm Sci· November 2025

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Intravitreal Sustained Release of Dexamethasone from a Self-Healing Injectable Hydrogel: An In Vivo Safety and Release Study.
Ada Annala, Amir Sadeghi, Elisa Toropainen, Annika Valtari, Jooseppi Puranen

Mol Pharm· November 2025

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Progressive rod bipolar cell loss, ubiquitin accumulation, and subretinal drusenoid deposits in Cln3Δex7/8 mice: New insights into juvenile neuronal ceroid lipofuscinosis pathogenesis.
Tommi Torsti, Toni Tamminen, Elisa Toropainen, Aaro Jalkanen, Anu Kauppinen

Exp Eye Res· November 2025

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Melanin-Binding-Based Discovery of Topically Instilled Carbonic Anhydrase Inhibitors for Targeted Delivery and Prolonged Action in the Eye.
Annika Valtari, Stanislav Kalinin, Janika Jäntti, Pekka Vanhanen, Martina Hanzlikova, Elisa Toropainen

Mol Pharm· February 2025

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Comprehensive ocular and systemic pharmacokinetics of dexamethasone after subconjunctival and intravenous injections in rabbits.
Annika Valtari, Susanna Posio, Elisa Toropainen, Anusha Balla, Jooseppi Puranen

Eur J Pharm Biopharm· May 2024

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Imaging, quantitation and kinetic modelling of intravitreal nanomaterials.
Amir Sadeghi, Marika Ruponen, Jooseppi Puranen, Shoupeng Cao, Roxane Ridolfo, Elisa Toropainen

Int J Pharm· June 2022

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Topical pharmacokinetics of dexamethasone suspensions in the rabbit eye: Bioavailability comparison.
Vatsala Naageshwaran, Veli-Pekka Ranta, Elisa Toropainen, Marjo Tuomainen, Glenwood Gum

Int J Pharm· March 2022

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Understanding dexamethasone kinetics in the rabbit tear fluid: Drug release and clearance from solution, suspension and hydrogel formulations.
Anusha Balla, Marika Ruponen, Annika Valtari, Elisa Toropainen, Marjo Tuomainen

Eur J Pharm Biopharm· March 2022

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Ocular metabolism and distribution of drugs in the rabbit eye: Quantitative assessment after intracameral and intravitreal administrations.
Eva M Del Amo, Anam Hammid, Melanie Tausch, Elisa Toropainen, Amir Sadeghi

Int J Pharm· February 2022

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Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice.
Toni Tamminen, Ali Koskela, Elisa Toropainen, Iswariyaraja Sridevi Gurubaran, Mateusz Winiarczyk

Oxid Med Cell Longev· February 2022

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SCD1-Fatty Acid Desaturase Inhibitor MF-438 Alleviates Latent Inflammation Induced by Preservative-Free Prostaglandin Analog Eye Drops.
Anna Pacwa, Joanna Machowicz, Alicja Wojtyniak, Marita Pietrucha-Dutczak, Elisa Toropainen

J Inflamm Res· February 2022

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Pharmacokinetics of Pullulan-Dexamethasone Conjugates in Retinal Drug Delivery.
Eva Kicková, Amir Sadeghi, Jooseppi Puranen, Shirin Tavakoli, Merve Sen, Elisa Toropainen

Pharmaceutics· December 2021

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Magnetically Assisted Drug Delivery of Topical Eye Drops Maintains Retinal Function In Vivo in Mice.
Marco Bassetto, Daniel Ajoy, Florent Poulhes, Cathy Obringer, Aurelie Walter, Elisa Toropainen

Pharmaceutics· October 2021

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Ocular pharmacokinetics of atenolol, timolol and betaxolol cocktail: Tissue exposures in the rabbit eye.
Anam Fayyaz, Kati-Sisko Vellonen, Veli-Pekka Ranta, Elisa Toropainen, Mika Reinisalo

Eur J Pharm Biopharm· September 2021

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Partitioning and Spatial Distribution of Drugs in Ocular Surface Tissues.
Anusha Balla, Seppo Auriola, Angus C Grey, Nicholas J Demarais, Annika Valtari, Elisa Toropainen

Pharmaceutics· May 2021

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Pharmacokinetics of intravitreal macromolecules: Scaling between rats and rabbits.
Amir Sadeghi, Jooseppi Puranen, Marika Ruponen, Annika Valtari, Astrid Subrizi, Elisa Toropainen

Eur J Pharm Sci· April 2021

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Intravitreal Polymeric Nanocarriers with Long Ocular Retention and Targeted Delivery to the Retina and Optic Nerve Head Region.
Vijayabhaskarreddy Junnuthula, Amir Sadeghi Boroujeni, Shoupeng Cao, Shirin Tavakoli, Roxane Ridolfo, Elisa Toropainen

Pharmaceutics· March 2021

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Biopharmaceutics of Topical Ophthalmic Suspensions: Importance of Viscosity and Particle Size in Ocular Absorption of Indomethacin.
Elisa Toropainen, Sara J Fraser-Miller, Dunja Novakovic, Eva M Del Amo, Kati-Sisko Vellonen

Pharmaceutics· March 2021

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Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of Double Knock-Out Mice.
Janusz Blasiak, Ali Koskela, Elzbieta Pawlowska, Mikko Liukkonen, Johanna Ruuth, Elisa Toropainen

Int J Mol Sci· February 2021

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Topical ocular pharmacokinetics and bioavailability for a cocktail of atenolol, timolol and betaxolol in rabbits.
Anam Fayyaz, Veli-Pekka Ranta, Elisa Toropainen, Kati-Sisko Vellonen, Annika Valtari

Eur J Pharm Sci· December 2020

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Release of functional dexamethasone by intracellular enzymes: A modular peptide-based strategy for ocular drug delivery.
Madhushree Bhattacharya, Amir Sadeghi, Sanjay Sarkhel, Marja Hagström, Sina Bahrpeyma, Elisa Toropainen

J Control Release· November 2020

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Microflow-Based Device for In Vitro and Ex Vivo Drug Permeability Studies.
Samu Hemmilä, Marika Ruponen, Elisa Toropainen, Unni Tengvall-Unadike, Arto Urtti

SLAS Technol· October 2020

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Characterization, Stability, and in Vivo Efficacy Studies of Recombinant Human CNTF and Its Permeation into the Neural Retina in ex Vivo Organotypic Retinal Explant Culture Models.
Jaakko Itkonen, Ada Annala, Shirin Tavakoli, Blanca Arango-Gonzalez, Marius Ueffing, Elisa Toropainen

Pharmaceutics· June 2020

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Design and synthesis of lipid-mimetic cationic iridium complexes and their liposomal formulation for and application in luminescent bioimaging.
Julia R Shakirova, Amir Sadeghi, Alla A Koblova, Pavel S Chelushkin, Elisa Toropainen

RSC Adv· April 2020

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