Publications by authors named "Elisabeth M van Leeuwen"

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Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.
Pieter W M Bonnemaijer, Elisabeth M van Leeuwen, Adriana I Iglesias, Puya Gharahkhani, Veronique Vitart

Commun Biol· July 2020

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Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
Nicole M Warrington, Robin N Beaumont, Momoko Horikoshi, Felix R Day, Øyvind Helgeland, Elisabeth M van Leeuwen

Nat Genet· May 2019

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Author Correction: Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Elisabeth M van Leeuwen

Nat Commun· January 2019

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Author Correction: Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
Valentina Iotchkova, Jie Huang, John A Morris, Deepti Jain, Caterina Barbieri, Elisabeth M van Leeuwen

Nat Genet· December 2018

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GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
Nora Franceschini, Claudia Giambartolomei, Paul S de Vries, Chris Finan, Joshua C Bis, Elisabeth M van Leeuwen

Nat Commun· December 2018

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A new perspective on lipid research in age-related macular degeneration.
Elisabeth M van Leeuwen, Eszter Emri, Benedicte M J Merle, Johanna M Colijn, Eveline Kersten

Prog Retin Eye Res· November 2018

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Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.
Adriana I Iglesias, Aniket Mishra, Veronique Vitart, Yelena Bykhovskaya, René Höhn, Elisabeth M van Leeuwen

Nat Commun· May 2018

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An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.
Robert A Scott, Laura J Scott, Reedik Mägi, Letizia Marullo, Kyle J Gaulton, Elisabeth M van Leeuwen

Diabetes· November 2017

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Haplotype reference consortium panel: Practical implications of imputations with large reference panels.
Adriana I Iglesias, Sven J van der Lee, Pieter W M Bonnemaijer, René Höhn, Abhishek Nag, Elisabeth M van Leeuwen

Hum Mutat· August 2017

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New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.
Henriët Springelkamp, Adriana I Iglesias, Aniket Mishra, René Höhn, Robert Wojciechowski, Elisabeth M van Leeuwen

Hum Mol Genet· January 2017

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Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.
Valentina Iotchkova, Jie Huang, John A Morris, Deepti Jain, Caterina Barbieri, Elisabeth M van Leeuwen

Nat Genet· November 2016

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A Combined Linkage and Exome Sequencing Analysis for Electrocardiogram Parameters in the Erasmus Rucphen Family Study.
Claudia T Silva, Irina V Zorkoltseva, Najaf Amin, Ayşe Demirkan, Elisabeth M van Leeuwen

Front Genet· November 2016

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Genome-wide associations for birth weight and correlations with adult disease.
Momoko Horikoshi, Robin N Beaumont, Felix R Day, Nicole M Warrington, Marjolein N Kooijman, Elisabeth M van Leeuwen

Nature· October 2016

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Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels.
Elisabeth M van Leeuwen, Aniko Sabo, Joshua C Bis, Jennifer E Huffman, Ani Manichaikul

J Med Genet· July 2016

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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia.
Amit V Khera, Hong-Hee Won, Gina M Peloso, Kim S Lawson, Traci M Bartz, Elisabeth M van Leeuwen

J Am Coll Cardiol· June 2016

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.
Johannes Kettunen, Ayşe Demirkan, Peter Würtz, Harmen H M Draisma, Toomas Haller, Elisabeth M van Leeuwen

Nat Commun· March 2016

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Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error.
Qiao Fan, Virginie J M Verhoeven, Robert Wojciechowski, Veluchamy A Barathi, Pirro G Hysi, Elisabeth M van Leeuwen

Nat Commun· March 2016

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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.
Kyle J Gaulton, Teresa Ferreira, Yeji Lee, Anne Raimondo, Reedik Mägi, Elisabeth M van Leeuwen

Nat Genet· December 2015

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Fine mapping the region reveals a common intronic insertion associated to HDL-C.
Elisabeth M van Leeuwen, Jennifer E Huffman, Joshua C Bis, Aaron Isaacs, Monique Mulder

NPJ Aging Mech Dis· November 2015

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WNT10A exonic variant increases the risk of keratoconus by decreasing corneal thickness.
Gabriel Cuellar-Partida, Henriët Springelkamp, Sionne E M Lucas, Seyhan Yazar, Alex W Hewitt, Elisabeth M van Leeuwen

Hum Mol Genet· September 2015

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Population-specific genotype imputations using minimac or IMPUTE2.
Elisabeth M van Leeuwen, Alexandros Kanterakis, Patrick Deelen, Mathijs V Kattenberg,

Nat Protoc· September 2015

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Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.
Momoko Horikoshi, Reedik Mӓgi, Martijn van de Bunt, Ida Surakka, Antti-Pekka Sarin, Elisabeth M van Leeuwen

PLoS Genet· July 2015

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The impact of low-frequency and rare variants on lipid levels.
Ida Surakka, Momoko Horikoshi, Reedik Mägi, Antti-Pekka Sarin, Anubha Mahajan, Elisabeth M van Leeuwen

Nat Genet· June 2015

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Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.
Harmen H M Draisma, René Pool, Michael Kobl, Rick Jansen, Ann-Kristin Petersen, Elisabeth M van Leeuwen

Nat Commun· June 2015

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