Publications by authors named "Elizabeth Beck"

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Distinguishing Collaboration From Other Group Work to Help Public Health and Other Sectors Solve Wicked Problems to Improve Health and Well-Being for All.
Leigh Alderman, Elizabeth Beck

Public Health Rep· November 2025

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Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M Muscarinic Acetylcholine Receptor.
Christopher R Butler, Michael Popiolek, Laura A McAllister, Erik A LaChapelle, Melissa Kramer, Elizabeth M Beck

J Med Chem· July 2024

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Stress, Resilience, and Coping of Healthcare Workers during the COVID-19 Pandemic.
Ivana T Croghan, Sherry S Chesak, Jayanth Adusumalli, Karen M Fischer, Elizabeth W Beck

J Prim Care Community Health· May 2021

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Synthesis and Structure-Activity Relationships of N-(4-Benzamidino)-Oxazolidinones: Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6.
Elena De Vita, Niels Smits, Helma van den Hurk, Elizabeth M Beck, Joanne Hewitt

ChemMedChem· January 2020

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Identification of A Novel Class of Benzofuran Oxoacetic Acid-Derived Ligands that Selectively Activate Cellular EPAC1.
Elizabeth M Beck, Euan Parnell, Angela Cowley, Alison Porter, Jonathan Gillespie

Cells· November 2019

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Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation.
Brian T O'Neill, Elizabeth M Beck, Christopher R Butler, Charles E Nolan, Cathleen Gonzales

J Med Chem· May 2018

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Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.
Lei Zhang, Laigao Chen, Jason K Dutra, Elizabeth M Beck, Sangram Nag

J Med Chem· April 2018

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Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase.
Christopher R Butler, Elizabeth M Beck, Anthony Harris, Zhen Huang, Laura A McAllister

J Med Chem· December 2017

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The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging.
Lei Zhang, Laigao Chen, Elizabeth M Beck, Thomas A Chappie, Richard V Coelho

J Med Chem· October 2017

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Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality.
Christopher R Butler, Kevin Ogilvie, Luis Martinez-Alsina, Gabriela Barreiro, Elizabeth M Beck

J Med Chem· January 2017

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Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors.
Andrea M Zuhl, Charles E Nolan, Michael A Brodney, Sherry Niessen, Kevin Atchison, Elizabeth M Beck

Nat Commun· October 2016

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Evidence of low toxicity of oil sands process-affected water to birds invites re-evaluation of avian protection strategies.
Elizabeth M Beck, Judit E G Smits, Colleen Cassady St Clair

Conserv Physiol· June 2016

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SPOTLIGHT ON ORNAC MEMBERS. AN INTERVIEW WITH ELIZABETH BECK RN, CPN(C), ORNAC TREASURER.
Elizabeth Beck, Andras Switzer

ORNAC J· June 2016

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"Nutcracker Fracture" in a Ballet Dancer Performing in The Nutcracker.
Sasha Carsen, Bridget J Quinn, Elizabeth Beck, Heather Southwick, Lyle J Micheli

J Dance Med Sci· September 2015

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Health of domestic mallards (Anas platyrhynchos domestica) following exposure to oil sands process-affected water.
Elizabeth M Beck, Judit E G Smits, Colleen Cassady St Clair

Environ Sci Technol· May 2015

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Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors.
Michael A Brodney, Elizabeth M Beck, Christopher R Butler, Gabriela Barreiro, Eric F Johnson

J Med Chem· April 2015

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Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug design.
Christopher R Butler, Michael A Brodney, Elizabeth M Beck, Gabriela Barreiro, Charles E Nolan

J Med Chem· March 2015

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Inclusion body myositis and chronic lymphocytic leukemia: a case series.
Elizabeth H Beck, Anthony A Amato, Steven A Greenberg

Neurology· July 2014

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Design and selection parameters to accelerate the discovery of novel central nervous system positron emission tomography (PET) ligands and their application in the development of a novel phosphodiesterase 2A PET ligand.
Lei Zhang, Anabella Villalobos, Elizabeth M Beck, Thomas Bocan, Thomas A Chappie

J Med Chem· June 2013

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The synthesis and in vivo evaluation of [18F]PF-9811: a novel PET ligand for imaging brain fatty acid amide hydrolase (FAAH).
Marc B Skaddan, Lei Zhang, Douglas S Johnson, Aijun Zhu, Kenneth R Zasadny, Elizabeth M Beck

Nucl Med Biol· October 2012

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Chemical synthesis of Aspidosperma alkaloids inspired by the reverse of the biosynthesis of the rhazinilam family of natural products.
Lindsay McMurray, Elizabeth M Beck, Matthew J Gaunt

Angew Chem Int Ed Engl· September 2012

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Chiral sulfinamide/achiral sulfonic acid cocatalyzed enantioselective protonation of enol silanes.
Elizabeth M Beck, Alan M Hyde, Eric N Jacobsen

Org Lett· August 2011

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Pd-catalyzed C-H bond functionalization on the indole and pyrrole nucleus.
Elizabeth M Beck, Matthew J Gaunt

Top Curr Chem· June 2011

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Letter to the editor.
Samer S Hasan, Marty Levy, Frank R Noyes, Stephanie A Moller, April Zambelli-Weiner, Charles L Beck, Elizabeth P Beck

Am J Sports Med· July 2010

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Oxidative Pd(II)-catalyzed C-H bond amination to carbazole at ambient temperature.
James A Jordan-Hore, Carin C C Johansson, Elizabeth M Beck, Matthew J Gaunt

J Am Chem Soc· December 2008

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