Publications by authors named "Elizabeth Doherty"

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Post-translational modifications of huntingtin's N17 region: implications for self-association and membrane binding.
Mariana Gallo, Raffaele Ingenito, Marco Finotto, Sara Di Marino, Daniel Cicero, Elizabeth M Doherty

Biochim Biophys Acta Mol Basis Dis· November 2025

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Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction.
Mitesh Rathod, Ryan N Stack, Sarah E Kubik, Stephanie A Huang, Chloe P Whitworth, Elizabeth L Doherty

Adv Sci (Weinh)· September 2025

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Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations.
Wen Yih Aw, Aanya Sawhney, Mitesh Rathod, Chloe P Whitworth, Elizabeth L Doherty

APL Bioeng· March 2025

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Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations.
Wen Yih Aw, Aanya Sawhney, Mitesh Rathod, Chloe P Whitworth, Elizabeth L Doherty

bioRxiv· December 2024

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P300 Modulates Endothelial Mechanotransduction of Fluid Shear Stress.
Chloe P Whitworth, Wen Y Aw, Elizabeth L Doherty, Chenchen Handler, Yogeshwari Ambekar

Cell Mol Bioeng· October 2024

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Human Cell-Derived Matrix Composite Hydrogels with Diverse Composition for Use in Vasculature-on-chip Models.
Elizabeth L Doherty, Grace Krohn, Emily C Warren, Alexandra Patton, Chloe P Whitworth

Adv Healthc Mater· July 2024

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Donor-Derived Engineered Microvessels for Cardiovascular Risk Stratification of Patients with Kidney Failure.
Mitesh L Rathod, Wen Yih Aw, Stephanie Huang, Jingming Lu, Elizabeth L Doherty

Small· June 2024

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Identification and Optimization of RNA-Splicing Modulators as Huntingtin Protein-Lowering Agents for the Treatment of Huntington's Disease.
Longbin Liu, Karine Malagu, Alan F Haughan, Vinod Khetarpal, Andrew J Stott, Elizabeth M Doherty

J Med Chem· September 2023

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Patient-derived extracellular matrix demonstrates role of COL3A1 in blood vessel mechanics.
Elizabeth L Doherty, Wen Yih Aw, Emily C Warren, Max Hockenberry, Chloe P Whitworth

Acta Biomater· August 2023

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Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation.
Wen Yih Aw, Crescentia Cho, Hao Wang, Anne Hope Cooper, Elizabeth L Doherty

Sci Adv· February 2023

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Developing HDAC4-Selective Protein Degraders To Investigate the Role of HDAC4 in Huntington's Disease Pathology.
Natsuko Macabuag, William Esmieu, Perla Breccia, Rebecca Jarvis, Wesley Blackaby, Elizabeth M Doherty

J Med Chem· September 2022

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Microfluidic and Organ-on-a-Chip Approaches to Investigate Cellular and Microenvironmental Contributions to Cardiovascular Function and Pathology.
Elizabeth L Doherty, Wen Yih Aw, Anthony J Hickey, William J Polacheck

Front Bioeng Biotechnol· February 2021

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Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13.
Cristina Cariulo, Margherita Verani, Paola Martufi, Raffaele Ingenito, Marco Finotto, Elizabeth M Doherty

Biochem Biophys Res Commun· January 2020

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Structure-guided Discovery of Dual-recognition Chemibodies.
Alan C Cheng, Elizabeth M Doherty, Sheree Johnstone, Erin F DiMauro, Jennifer Dao

Sci Rep· May 2018

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New changes in US patent term adjustment calculations after Novartis v. Lee.
Elizabeth A Doherty, Rebecca M McNeill

Pharm Pat Anal· February 2016

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What service users with psychotic disorders want in a mental health crisis or relapse: thematic analysis of joint crisis plans.
Simone Farrelly, Gill Brown, Diana Rose, Elizabeth Doherty, R Claire Henderson

Soc Psychiatry Psychiatr Epidemiol· October 2014

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Disubstituted 1-aryl-4-aminopiperidine library synthesis using computational drug design and high-throughput batch and flow technologies.
Marian C Bryan, Christopher D Hein, Hua Gao, Xiaoyang Xia, Heather Eastwood, Elizabeth M Doherty

ACS Comb Sci· September 2013

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N-substituted azaindoles as potent inhibitors of Cdc7 kinase.
Marian C Bryan, James R Falsey, Mike Frohn, Andreas Reichelt, Guomin Yao, Elizabeth M Doherty

Bioorg Med Chem Lett· April 2013

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2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors.
Zihao Hua, Xin Huang, Howard Bregman, Nagasree Chakka, Erin F DiMauro, Elizabeth M Doherty

Bioorg Med Chem Lett· September 2012

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Evaluation of a commercial packed bed flow hydrogenator for reaction screening, optimization, and synthesis.
Marian C Bryan, David Wernick, Christopher D Hein, James V Petersen, John W Eschelbach, Elizabeth M Doherty

Beilstein J Org Chem· August 2012

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Admission hyperglycemia and acute myocardial infarction: outcomes and potential therapies for diabetics and nondiabetics.
Anjan K Chakrabarti, Priyamvada Singh, Lakshmi Gopalakrishnan, Varun Kumar, Meagan Elizabeth Doherty

Cardiol Res Pract· August 2012

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Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors.
Marian C Bryan, Douglas A Whittington, Elizabeth M Doherty, James R Falsey, Alan C Cheng

J Med Chem· February 2012

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Discovery of potent and highly selective thienopyridine Janus kinase 2 inhibitors.
Laurie B Schenkel, Xin Huang, Alan Cheng, Holly L Deak, Elizabeth Doherty

J Med Chem· December 2011

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Discovery of pyridazinopyridinones as potent and selective p38 mitogen-activated protein kinase inhibitors.
Bin Wu, Hui-Ling Wang, Liping Pettus, Ryan P Wurz, Elizabeth M Doherty

J Med Chem· September 2010

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Structure-activity relationship (SAR) investigations of tetrahydroquinolines as BKCa agonists.
Vijay K Gore, Vu V Ma, Ruoyuan Yin, Joe Ligutti, David Immke, Elizabeth M Doherty

Bioorg Med Chem Lett· June 2010

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