Publications by authors named "Elizabeth Lopes"

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Hybrid molecules of protoflavones and spirooxindole derivatives with selective cytotoxicity against triple-negative breast cancer cells.
Gábor Girst, Elizabeth A Lopes, Lídia M Gonçalves, Margarida Espadinha, Norbert Kúsz

RSC Med Chem· September 2023

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Antimalarial drugs: what's new in the patents?
Elizabeth A Lopes, Maria M M Santos, Mattia Mori

Expert Opin Ther Pat· March 2023

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Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors.
Margarida Espadinha, Elizabeth A Lopes, Vanda Marques, Joana D Amaral, Daniel J V A Dos Santos

Eur J Med Chem· November 2022

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Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity.
Elizabeth A Lopes, Raquel Mestre, Diana Fontinha, Jenny Legac, Jinxin V Pei

Eur J Med Chem· June 2022

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Mutant p53 reactivator SLMP53-2 hinders ultraviolet B radiation-induced skin carcinogenesis.
Joana B Loureiro, Rita Ribeiro, Nair Nazareth, Tiago Ferreira, Elizabeth A Lopes

Pharmacol Res· January 2022

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Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer.
Valentina Barcherini, Joana Almeida, Elizabeth A Lopes, Mi Wang, Diogo Magalhães E Silva

ChemMedChem· January 2021

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Small Molecules Targeting Mutant P53: A Promising Approach for Cancer Treatment.
Elizabeth A Lopes, Sara Gomes, Lucília Saraiva, Maria M M Santos

Curr Med Chem· February 2020

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An Update on MDMX and Dual MDM2/X Inhibitors.
Margarida Espadinha, Valentina Barcherini, Elizabeth A Lopes, Maria M M Santos

Curr Top Med Chem· August 2018

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The tubular compartment and the spermatogenic dynamics of the wild rodent Oxymycterus nasutus (Rodentia: Cricetidae).
Ana Carolina Torre Morais, Maytê Koch Balarini, Elizabeth Oliveira Lopes, Tatiana Prata Menezes, Fernando Marques Quintela

Anim Reprod Sci· October 2014

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Properties of slow- and fast-twitch muscle fibres in a mouse model of amyotrophic lateral sclerosis.
Julie D Atkin, Rachel L Scott, Jan M West, Elizabeth Lopes, Alvin K J Quah

Neuromuscul Disord· May 2005

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Loss of synaptophysin-positive boutons on lumbar motor neurons innervating the medial gastrocnemius muscle of the SOD1G93A G1H transgenic mouse model of ALS.
Da Wei Zang, Elizabeth C Lopes, Surindar S Cheema

J Neurosci Res· March 2005

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Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis.
Bradley J Turner, Julie D Atkin, Manal A Farg, Da Wei Zang, Alan Rembach, Elizabeth C Lopes

J Neurosci· January 2005

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Brain beta-amyloid accumulation in transgenic mice expressing mutant superoxide dismutase 1.
Bradley J Turner, Qiao-Xin Li, Katrina M Laughton, Colin L Masters, Elizabeth C Lopes

Neurochem Res· December 2004

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Effect of p75 neurotrophin receptor antagonist on disease progression in transgenic amyotrophic lateral sclerosis mice.
Bradley J Turner, Simon S Murray, Loretta G Piccenna, Elizabeth C Lopes, Trevor J Kilpatrick

J Neurosci Res· October 2004

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Magnetic resonance imaging reveals neuronal degeneration in the brainstem of the superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis.
Da Wei Zang, Qing Yang, Hong Xin Wang, Gary Egan, Elizabeth C Lopes

Eur J Neurosci· October 2004

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Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS.
Alan Rembach, Bradley J Turner, Stephen Bruce, Irwin K Cheah, Rachel L Scott, Elizabeth C Lopes

J Neurosci Res· August 2004

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Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
Bradley J Turner, Elizabeth C Lopes, Surindar S Cheema

J Cell Biochem· April 2004

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Antisense peptide nucleic acid-mediated knockdown of the p75 neurotrophin receptor delays motor neuron disease in mutant SOD1 transgenic mice.
Bradley J Turner, Irwin K Cheah, Katherine J Macfarlane, Elizabeth C Lopes, Steven Petratos

J Neurochem· November 2003

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Neuromuscular accumulation of mutant superoxide dismutase 1 aggregates in a transgenic mouse model of familial amyotrophic lateral sclerosis.
Bradley J Turner, Elizabeth C Lopes, Surindar S Cheema

Neurosci Lett· October 2003

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Behavioural and anatomical effects of systemically administered leukemia inhibitory factor in the SOD1(G93A G1H) mouse model of familial amyotrophic lateral sclerosis.
Michael F Azari, Elizabeth C Lopes, Chantelle Stubna, Bradley J Turner, Dawei Zang

Brain Res· August 2003

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Design and application of a peptide nucleic acid sequence targeting the p75 neurotrophin receptor.
Irwin K Cheah, Surindar S Cheema, Steven J Langford, Elizabeth C Lopes, Katherine J Macfarlane

Bioorg Med Chem Lett· July 2003

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Low-affinity neurotrophin receptor with targeted mutation of exon 3 is capable of mediating the death of axotomized neurons.
Simon S Murray, Perry F Bartlett, Elizabeth C Lopes, Elizabeth J Coulson, Una Greferath

Clin Exp Pharmacol Physiol· April 2003

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Schwann cell apoptosis in the postnatal axotomized sciatic nerve is mediated via NGF through the low-affinity neurotrophin receptor.
Steven Petratos, Helmut Butzkueven, Kylie Shipham, Helen Cooper, Tamara Bucci, Elizabeth Lopes

J Neuropathol Exp Neurol· April 2003

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