Publications by authors named "Elizabeth Topp"

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Comparative Analysis of mRNA Degradation Kinetics Using Chromatographic and Electrophoretic Methods.
Caio H N Barros, Manuel Alfaro, Agota Csiki-Fejer, Bakul Bhatnagar, Serguei Tschessalov, Elizabeth M Topp

Mol Pharm· June 2025

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Introducing the Special Issue on "Advances in Small and Large Molecule Pharmaceutics Research across Ireland".
Gavin P Andrews, Anne Marie Healy, Elizabeth M Topp

Mol Pharm· August 2024

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A Model Study to Assess Fibrillation and Product Stability to Support Peptide Drug Design.
Harshil K Renawala, Karthik B Chandrababu, Katelyn J Smith, Suzanne M D'Addio, Elizabeth M Topp

Mol Pharm· May 2024

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Investigation of the Solid-State Interactions in Lyophilized Human G-CSF Using Hydrogen-Deuterium Exchange Mass Spectrometry.
Victoria E Wood, Mark-Adam Kellerman, Kate Groves, Milena Quaglia, Elizabeth M Topp

Mol Pharm· April 2024

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Effect of Atomic Layer Coating on the Stability of Solid Myoglobin Formulations.
Caio H N Barros, Manuel Alfaro, Cormac Costello, Fei Wang, Kedar Sapre, Elizabeth M Topp

Mol Pharm· August 2023

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Fibrillation of human insulin B-chain by pulsed hydrogen-deuterium exchange mass spectrometry.
Harshil K Renawala, Elizabeth M Topp

Biophys J· December 2022

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Statistical electromagnetics for industrial pharmaceutical lyophilization.
Ahmed Abdelraheem, Rishabh Tukra, Petr Kazarin, Michael D Sinanis, Elizabeth M Topp

PNAS Nexus· July 2022

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Effect of 'pH' on the Rate of Pyroglutamate Formation in Solution and Lyophilized Solids.
Lia M Bersin, Sajal M Patel, Elizabeth M Topp

Mol Pharm· August 2021

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Understanding the Impact of Protein-Excipient Interactions on Physical Stability of Spray-Dried Protein Solids.
Yuan Chen, Jing Ling, Mingyue Li, Yongchao Su, Kinnari Santosh Arte, Elizabeth M Topp

Mol Pharm· July 2021

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Stability of antibody drug conjugate formulations evaluated using solid-state hydrogen-deuterium exchange mass spectrometry.
Eunbi Cho, Brendan M Mayhugh, Jayasree M Srinivasan, Gregory A Sacha, Steven L Nail, Elizabeth M Topp

J Pharm Sci· June 2021

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Effects of temperature and relative humidity in DO on solid-state hydrogen deuterium exchange mass spectrometry (ssHDX-MS).
Rishabh Tukra, Sam Gardner, Elizabeth M Topp

Int J Pharm· March 2021

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Effects of drying method and excipient on the structure and physical stability of protein solids: Freeze drying vs. spray freeze drying.
Tarun Tejasvi Mutukuri, Nathan E Wilson, Lynne S Taylor, Elizabeth M Topp, Qi Tony Zhou

Int J Pharm· February 2021

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Fibrillation of Human Calcitonin and Its Analogs: Effects of Phosphorylation and Disulfide Reduction.
Harshil K Renawala, Karthik B Chandrababu, Elizabeth M Topp

Biophys J· January 2021

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Effects of Secondary Structure on Solid-State Hydrogen-Deuterium Exchange in Model α-Helix and β-Sheet Peptides.
Rajashekar Kammari, Elizabeth M Topp

Mol Pharm· September 2020

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Prehydration and the Reversibility of Solid-State Hydrogen-Deuterium Exchange.
Rajashekar Kammari, Elizabeth M Topp

Mol Pharm· September 2020

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A Novel Photoreactive Excipient to Probe Peptide-Matrix Interactions in Lyophilized Solids.
Yuan Chen, Elizabeth M Topp

J Pharm Sci· January 2020

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Surface Composition and Formulation Heterogeneity of Protein Solids Produced by Spray Drying.
Nathan E Wilson, Tarun Tejasvi Mutukuri, Dmitry Y Zemlyanov, Lynne S Taylor, Elizabeth M Topp

Pharm Res· December 2019

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Optimizing the Formulation and Lyophilization Process for a Fragment Antigen Binding (Fab) Protein Using Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry (ssHDX-MS).
Lokesh Kumar, Karthik Balakrishna Chandrababu, Shenbaga Moorthy Balakrishnan, Andrea Allmendinger, Benjamin Walters, Elizabeth M Topp

Mol Pharm· November 2019

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Effects of ionic interactions on protein stability prediction using solid-state hydrogen deuterium exchange with mass spectrometry (ssHDX-MS).
Mohamed H H AbouGhaly, Jiali Du, Sajal M Patel, Elizabeth M Topp

Int J Pharm· September 2019

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Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS).
Nathan E Wilson, Elizabeth M Topp, Qi Tony Zhou

Int J Pharm· August 2019

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Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry (ssHDX-MS) of Lyophilized Poly-d,l-Alanine.
Rajashekar Kammari, Elizabeth M Topp

Mol Pharm· July 2019

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Photolytic Labeling To Quantify Peptide-Water Interactions in Lyophilized Solids.
Yuan Chen, Elizabeth M Topp

Mol Pharm· March 2019

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Photolytic Labeling and Its Applications in Protein Drug Discovery and Development.
Yuan Chen, Elizabeth M Topp

J Pharm Sci· February 2019

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Quantitative Analysis of Peptide-Matrix Interactions in Lyophilized Solids Using Photolytic Labeling.
Yuan Chen, Elizabeth M Topp

Mol Pharm· July 2018

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In-Situ Molecular Vapor Composition Measurements During Lyophilization.
Evan T Liechty, Andrew D Strongrich, Ehab M Moussa, Elizabeth Topp, Alina A Alexeenko

Pharm Res· April 2018

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