Publications by authors named "Ella Lineham"

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Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse.
Anthony K Edmonds, Dimitrios-Ilias Balourdas, Graham P Marsh, Robert Felix, Bradley Brasher, Ella Lineham

J Med Chem· May 2025

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Transition of patients with Gaucher disease type 1 from pediatric to adult care: results from two international surveys of patients and health care professionals.
Karolina M Stepien, Irena Žnidar, Beata Kieć-Wilk, Angel Jones, Daniela Castillo-García, Ella Lineham

Front Pediatr· August 2024

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Probing the Anticancer Action of Novel Ferrocene Analogues of MNK Inhibitors.
Supojjanee Sansook, Ella Lineham, Storm Hassell-Hart, Graham J Tizzard, Simon J Coles

Molecules· August 2018

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Synergistic effects of inhibiting the MNK-eIF4E and PI3K/AKT/ mTOR pathways on cell migration in MDA-MB-231 cells.
Ella Lineham, Graham J Tizzard, Simon J Coles, John Spencer, Simon J Morley

Oncotarget· March 2018

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Dual abrogation of MNK and mTOR: a novel therapeutic approach for the treatment of aggressive cancers.
Ella Lineham, John Spencer, Simon J Morley

Future Med Chem· September 2017

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The helicase, DDX3X, interacts with poly(A)-binding protein 1 (PABP1) and caprin-1 at the leading edge of migrating fibroblasts and is required for efficient cell spreading.
Alice C Copsey, Simon Cooper, Robert Parker, Ella Lineham, Cuzack Lapworth

Biochem J· August 2017

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