Publications by authors named "Ellis Jaffray"

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PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways.
Ellis G Jaffray, Michael H Tatham, Barbara Mojsa, Anna Plechanovová, Alejandro Rojas-Fernandez

J Cell Biol· June 2025

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The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.
Ellis G Jaffray, Michael H Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez

J Cell Biol· April 2023

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Functional 3D architecture in an intrinsically disordered E3 ligase domain facilitates ubiquitin transfer.
Paul Murphy, Yingqi Xu, Sarah L Rouse, Ellis G Jaffray, Anna Plechanovová

Nat Commun· July 2020

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Sumoylation regulates protein dynamics during meiotic chromosome segregation in oocytes.
Federico Pelisch, Laura Bel Borja, Ellis G Jaffray, Ronald T Hay

J Cell Sci· July 2019

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A SUMO-Dependent Protein Network Regulates Chromosome Congression during Oocyte Meiosis.
Federico Pelisch, Triin Tammsalu, Bin Wang, Ellis G Jaffray, Anton Gartner

Mol Cell· January 2017

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Loss of ubiquitin E2 Ube2w rescues hypersensitivity of Rnf4 mutant cells to DNA damage.
Jean-François Maure, Sandra C Moser, Ellis G Jaffray, Arno F Alpi, Ronald T Hay

Sci Rep· May 2016

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Proteome-wide identification of SUMO modification sites by mass spectrometry.
Triin Tammsalu, Ivan Matic, Ellis G Jaffray, Adel F M Ibrahim, Michael H Tatham

Nat Protoc· September 2015

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Structural basis for the RING-catalyzed synthesis of K63-linked ubiquitin chains.
Emma Branigan, Anna Plechanovová, Ellis G Jaffray, James H Naismith, Ronald T Hay

Nat Struct Mol Biol· August 2015

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Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers.
John S Bett, Maria Stella Ritorto, Richard Ewan, Ellis G Jaffray, Satpal Virdee

Biochem J· March 2015

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Sp100 isoform-specific regulation of human adenovirus 5 gene expression.
Julia Berscheminski, Peter Wimmer, Juliane Brun, Wing Hang Ip, Peter Groitl, Ellis Jaffray

J Virol· June 2014

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Proteome-wide identification of SUMO2 modification sites.
Triin Tammsalu, Ivan Matic, Ellis G Jaffray, Adel F M Ibrahim, Michael H Tatham

Sci Signal· April 2014

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SUMO chain-induced dimerization activates RNF4.
Alejandro Rojas-Fernandez, Anna Plechanovová, Neil Hattersley, Ellis Jaffray, Michael H Tatham

Mol Cell· March 2014

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A role for paralog-specific sumoylation in histone deacetylase 1 stability.
Simona Citro, Ellis Jaffray, Ronald T Hay, Christian Seiser, Susanna Chiocca

J Mol Cell Biol· December 2013

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BC-box protein domain-related mechanism for VHL protein degradation.
Maria Elena Pozzebon, Archana Varadaraj, Domenico Mattoscio, Ellis G Jaffray, Claudia Miccolo

Proc Natl Acad Sci U S A· November 2013

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Ube2W conjugates ubiquitin to α-amino groups of protein N-termini.
Michael H Tatham, Anna Plechanovová, Ellis G Jaffray, Helena Salmen, Ronald T Hay

Biochem J· July 2013

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Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis.
Anna Plechanovová, Ellis G Jaffray, Michael H Tatham, James H Naismith, Ronald T Hay

Nature· September 2012

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SUMOylation of HNF4α regulates protein stability and hepatocyte function.
Wenli Zhou, Zara Hannoun, Ellis Jaffray, Claire N Medine, James R Black

J Cell Sci· August 2012

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Absolute SILAC-compatible expression strain allows Sumo-2 copy number determination in clinical samples.
Ivan Matic, Ellis G Jaffray, Senga K Oxenham, Michael J Groves, Christopher L R Barratt

J Proteome Res· October 2011

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Mechanism of ubiquitylation by dimeric RING ligase RNF4.
Anna Plechanovová, Ellis G Jaffray, Stephen A McMahon, Kenneth A Johnson, Iva Navrátilová

Nat Struct Mol Biol· August 2011

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Functional interactions between ubiquitin E2 enzymes and TRIM proteins.
Luisa M Napolitano, Ellis G Jaffray, Ronald T Hay, Germana Meroni

Biochem J· March 2011

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The SUMO protease SENP6 is a direct regulator of PML nuclear bodies.
Neil Hattersley, Linnan Shen, Ellis G Jaffray, Ronald T Hay

Mol Biol Cell· January 2011

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Post-translational modification by SUMO.
Zara Hannoun, Sebastian Greenhough, Ellis Jaffray, Ronald T Hay, David C Hay

Toxicology· December 2010

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Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies.
Marie-Claude Geoffroy, Ellis G Jaffray, Katherine J Walker, Ronald T Hay

Mol Biol Cell· December 2010

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SUMOylation of the GTPase Rac1 is required for optimal cell migration.
Sonia Castillo-Lluva, Michael H Tatham, Richard C Jones, Ellis G Jaffray, Ricky D Edmondson

Nat Cell Biol· November 2010

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Iso--tanapartholides: Isolation, Synthesis and Biological Evaluation.
Edward F Makiyi, Raquel F M Frade, Tomas Lebl, Ellis G Jaffray, Susan E Cobb

European J Org Chem· November 2009

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